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Dennis OConnor

UBC Medicine - Educational Media - YouTube - 0 views

www.youtube.com/about

neuroscience

shared by Dennis OConnor on 21 Apr 23 - No Cached
  • Dennis OConnor on 21 Apr 23
     
    "www.education.med.bc.ca" Our mighty EdTech team produces cinematic educational experiences: video, audio, interactive, simulated, narrative & virtual. We welcome collaborations from our international learning community. The Digital Solutions' EdTech team facilitates innovation by UBC Medicine learners and faculty. Website: www.education.med.bc.ca Subscribe: https://www.youtube.com/ubcmedvid?sub_confirmation=1 UBCMLN Podcast Network: https://tinyurl.com/ubcmedicinelearningnetwork Follow us for more content on all social media channels: @ubcmedvid The UBC Medical Program is situated on the traditional territories of indigenous peoples. We honour our hosts' graciousness for the students who seek knowledge here. © 2013-2022 UBC Faculty of Medicine, University of British Columbia. Vancouver, Canada. All rights reserved. Reproduction & distribution of this presentation without written permission from UBC Faculty of Medicine is prohibited.
Dennis OConnor

Katie Teague on Vimeo - 0 views

vimeo.com/stormcloudmedia

storytelling

shared by Dennis OConnor on 10 Mar 20 - No Cached
  • Dennis OConnor on 10 Mar 20
     
    "Katie Teague is an independent documentary filmmaker and multi-media mystic working in the realm of transformational storytelling."
Dennis OConnor

Understanding Medical Research: Your Facebook Friend is Wrong | Coursera - 0 views

www.coursera.org/...medical-research

research facebook

shared by Dennis OConnor on 03 Mar 21 - No Cached
  • Dennis OConnor on 03 Mar 21
     
    Recommended by Trish Makowiak: How can you tell if the bold headlines seen on social media are truly touting the next big thing or if the article isn't worth the paper it's printed on? Understanding Medical Studies, will provide you with the tools and skills you need to critically interpret medical studies, and determine for yourself the difference between good and bad science. The course covers study-design, research methods, and statistical interpretation. It also delves into the dark side of medical research by covering fraud, biases, and common misinterpretations of data. Each lesson will highlight case-studies from real-world journal articles. By the end of this course, you'll have the tools you need to determine the trustworthiness of the scientific information you're reading and, of course, whether or not your Facebook friend is wrong. This course was made possible in part by the George M. O'Brien Kidney Center at Yale.
Dennis OConnor

Healthcare Text Analytics: Unlocking the Evidence from Free Text | Frontiers Research T... - 0 views

www.frontiersin.org/...ng-the-evidence-from-free-text

GBD AI analytics healthcare research

shared by Dennis OConnor on 03 Feb 21 - No Cached
  • Dennis OConnor on 03 Feb 21
     
    "About this Research Topic Healthcare narratives (such as clinical notes, discharge letters, nurse handover notes, imaging reports, patients posts on social media or feedback comments, etc.) have been used as a key communication stream that contains the majority of actionable and contextualised data, but which - despite being increasingly available in a digital form - is still not routinely analysed, and is rarely integrated with other healthcare data on a large-scale. There are many barriers and challenges in processing healthcare free text, including, for example, the variability and implicit nature of language expressions, and difficulties in sharing training and evaluation data. On the other hand, recent years have witnessed increasing needs and opportunities to process free text, with a number of success stories that have demonstrated the feasibility of using advanced Natural Language Processing to unlock evidence contained in free text to support clinical care, patient self-management, epidemiological research and audit."
Dennis OConnor

Covid-19 "long haulers" are organizing online to study themselves | MIT Technology Review - 0 views

www.technologyreview.com/...ing-online-to-study-themselves

covid research citizen-science self-study

shared by Dennis OConnor on 21 Aug 20 - No Cached
  • Dennis OConnor on 21 Aug 20
     
    "Slack groups and social media are connecting people who've never fully recovered from coronavirus to collect data on their condition."
Dennis OConnor

The Power of Advocating Through Music | Rachelle Babler | TEDxWestMonroe - 0 views

www.youtube.com/watch

patient-experience advocacy empowered-patient Project-Apollo-Circle

shared by Dennis OConnor on 21 Dec 21 - No Cached
  • Dennis OConnor on 21 Dec 21
     
    "Rachelle Babler explores the untapped powers of combining music and advocacy to create human impact. She did this after losing her sister to colon cancer to create awareness around prevention and screening. The response was overwhelming. While many have advocated through speeches, fundraisers and media, very few advocate through songwriting and music. Maybe music will be the critical voice that creates the awakening to help us unite, during times of chaos and separation. When we are divided by speech, we can be united and reunited through the power of song. Rachelle Babler grew up in Southern California near the sunny beaches of San Diego and has always been an avid explorer, traveler, musician and creative soul. At the height of her career in forensics, she quit her job cold turkey to pursue her "why" and found out what that was during a global pandemic, "TO empower others to consciously advocate, SO THAT they can heal, inspire and unite the human collective". She is a #1 International Best Selling Co-Author, Speaker, Advocate. Singer/Songwriter and proud mother to her two amazing children, Austin and Camryn. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx"
Dennis OConnor

ŌURA + Helsinki Design Museum - How did you sleep last night? - 1 views

designmuseum.ouraring.com

tracking design-thinking Apollo ecosystem

shared by Dennis OConnor on 08 Nov 19 - No Cached
  • Dennis OConnor on 08 Nov 19
     
    "Want to see your sleep data at the Helsinki Design Museum? ŌURA is proud to be participating in "Enter and Encounter", a joint exhibition by Helsinki Design Museum and the Finnish Association of Designers Ornamo. This unique exhibition celebrates contemporary Finnish design and Finland's centenary anniversary. As part of the exhibition, we are happy to invite 100 active ŌURA users to share their sleep data and participate in the media installation "How did you sleep last night?"."
Dennis OConnor

This Is How We Beat the Coronavirus - The Atlantic - 1 views

www.theatlantic.com/...608389

covid testing research

shared by Dennis OConnor on 20 Mar 20 - No Cached
  • We’re closing schools and businesses and committing to social (really, physical) distancing. But as the sobering charts from the analysis show, this isn’t enough.
  • Asian countries have engaged in suppression; we are only engaging in mitigation.
  • At the moment, we can’t even test everyone who is sick.
  • ...15 more annotations...
  • Testing will allow us to isolate the infected so they can’t infect others. We need to be vigilant, and willing to quarantine people with absolute diligence.
  • To achieve this, we need to test many, many people, even those without symptoms.
  • buried in the Imperial College report is reason for optimism. The analysis finds that in the do-nothing scenario, many people die and die quickly. With serious mitigation, though, many of the measures we’re taking now slow things down. By the summer, the report calculates, the number of people who become sick will eventually reduce to a trickle.
  • Our efforts are good, temporizing measures.
  • Social distancing cannot prevent these infections, as they’ve already happened. Therefore, things will appear to get worse for some time, even if what we’re doing is making things better in the long run.
  • Our primary approach is social distancing—asking people to stay away from one another.
  • We can create a third path. We can decide to meet this challenge head-on. It is absolutely within our capacity to do so. We could develop tests that are fast, reliable, and ubiquitous. If we screen everyone, and do so regularly, we can let most people return to a more normal life. We can reopen schools and places where people gather. If we can be assured that the people who congregate aren’t infectious, they can socialize.
  • We can build health-care facilities that do rapid screening and care for people who are infected, apart from those who are not.
  • We can even commit to housing infected people apart from their healthy family members, to prevent transmission in households.
  • We will need to massively strengthen our medical infrastructure. We will need to build ventilators and add hospital beds. We will need to train and redistribute physicians, nurses, and respiratory therapists to where they are most needed. We will need to focus our factories on turning out the protective equipment—masks, gloves, gowns, and so forth—to ensure we keep our health-care workforce safe.
  • most importantly, we need to pour vast sums of intellectual and financial resources into developing a vaccine that would finally bring this nightmare to a close
  • If we commit to social distancing, however, at some point in the next few months the rate of spread will slow. We’ll be able to catch our breath. We’ll be able to ease restrictions, as some early hit countries are doing. We can move toward some semblance of normalcy.
  • The temptation then will be to think we have made it past the worst. We cannot give in to that temptation. That will be the time to redouble our efforts. We will need to prepare for the coming storm. We’ll need to build up our stockpiles, create strategies, and get ready.
  • We need to keep time on the clock, time to find a treatment or a vaccine.
  • We all have a choice to make. We can look at the coming fire and let it burn. We can hunker down, and hope to wait it out—or we can work together to get through it with as little damage as possible.
Dennis OConnor

About Us | The Redford Center - 0 views

redfordcenter.org/about-us

storytellling video

shared by Dennis OConnor on 11 Jun 18 - No Cached
  • Dennis OConnor on 11 Jun 18
     
    "About Us Co-founded in 2005 by Robert Redford and his son and board chair, James Redford, The Redford Center harnesses the power of film, video and new media to engage people through inspiring stories that galvanize environmental action. Drawing on the family's multi-generational expertise in filmmaking and activism, we produce, fund and fiscally sponsor impact-driven productions that showcase stories of individuals taking action to protect and restore the planet."
Dennis OConnor

Researchers Cast Doubt On Theory Of Coronavirus Lab Accident : Goats and Soda : NPR - 1 views

www.npr.org/...ry-of-coronavirus-lab-accident

covid research origins-covid-19

shared by Dennis OConnor on 24 Apr 20 - No Cached
  • April 23, 2020
  • Virus researchers say there is virtually no chance that the new coronavirus was released as result of a laboratory accident in China or anywhere else.
  • after corresponding with 10 leading scientists who collect samples of viruses from animals in the wild, study virus genomes and understand how lab accidents can happen, NPR found that an accidental release would have required a remarkable series of coincidences and deviations from well-established experimental protocols.
  • ...12 more annotations...
  • All of the evidence points to this not being a laboratory accident," says Jonna Mazet, a professor of epidemiology at the University of California, Davis and director of a global project to watch for emerging viruses called PREDICT.
  • all believe that the virus was transmitted between animals and humans in nature, as has happened in previous outbreaks — from Ebola to the Marburg virus — and with other known coronaviruses such as SARS and MERS.
  • Rather than a laboratory misstep, researchers believe that this new coronavirus reached humans in the same way that other coronaviruses have: through "zoonotic spillover," or humans picking up pathogens from wildlife.
  • the exact route from nature to people remains a mystery,
  • Regardless, genetic analysis shows the virus began to spread sometime in the fall or winter of 2019, says Robert Garry, a microbiologist at Tulane University. Those same analyses refuted an earlier theory that the virus was genetically engineered in a laboratory.
  • The CDC estimates that 6 out of 10 infectious diseases in people come from animals, including diseases caused by coronaviruses.
  • "As we change the landscape to suit our purposes, we come more and more into contact with viruses and other pathogens that we don't have much exposure to," says Dr. Brian Bird, associate director of the OneHealth Institute at UC Davis School of Veterinary Medicine and a former CDC scientist.
  • "Zoonotic transmission" or "zoonotic spillover" generally happens three ways: through excretion (feces that comes into contact with humans), slaughter (meat consumed by humans) and vector-borne (an animal biting a human). But even under these circumstances, the virus must then overcome barriers within the human body, defeating the immune system, to successfully replicate and transmit between humans themselves.
  • Despite the evidence, misinformation about the virus's origins continue to proliferate. For Daszak, who has worked on other outbreaks, the pattern is all too familiar: "Every time we get a new virus emerging, we have people that say, 'This could have come from a lab,' " he says.
  • "It's a real shame that the conspiracy theories can get to the level they've got with policymakers,"
  • The political heat has strained the very scientific collaborations meant to detect these viruses as they emerge, warns Jonna Mazet.
  • Daszak says the time for finger-pointing is over. "We have a bat virus in my neighborhood in New York killing people," he says. "Let's get real about this."
  • Dennis OConnor on 24 Apr 20
     
    "April 23, 2020"
Dennis OConnor

COVID-19 Testing Project - Pre-print manuscript - 0 views

covidtestingproject.org

covid antibodies testing preprint

shared by Dennis OConnor on 26 Apr 20 - No Cached
  • April 24, 2020: Read our pre-print manuscript. This is a preliminary report of work that has not been certified by peer review. This should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
  • Dennis OConnor on 26 Apr 20
     
    "We are a multidisciplinary team of researchers and physicians at UCSF, UC Berkeley, Chan Zuckerberg Biohub, and Innovative Genomics Institute."
Dennis OConnor

A mysterious company's coronavirus papers in top medical journals may be unraveling | S... - 0 views

www.sciencemag.org/...cal-journals-may-be-unraveling

covid research systematic-reviews

shared by Dennis OConnor on 03 Jun 20 - No Cached
  • On its face, it was a major finding: Antimalarial drugs touted by the White House as possible COVID-19 treatments looked to be not just ineffective, but downright deadly. A study published on 22 May in The Lancet used hospital records procured by a little-known data analytics company called Surgisphere to conclude that coronavirus patients taking chloroquine or hydroxychloroquine were more likely to show an irregular heart rhythm—a known side effect thought to be rare—and were more likely to die in the hospital. Within days, some large randomized trials of the drugs—the type that might prove or disprove the retrospective study’s analysis—screeched to a halt. Solidarity, the World Health Organization’s (WHO’s) megatrial of potential COVID-19 treatments, paused recruitment into its hydroxychloroquine arm, for example.
  • The study doesn’t properly control for the likelihood that patients getting the experimental drugs were sicker than the controls
  • Other researchers were befuddled by the data themselves. Though 66% of the patients were reportedly treated in North America, the reported doses tended to be higher than the guidelines set by the U.S. Food and Drug Administration, White notes. The authors claim to have included 4402 patients in Africa, 561 of whom died, but it seems unlikely that African hospitals would have detailed electronic health records for so many patients, White says.
  • ...9 more annotations...
  • This was very, very annoying, that The Lancet were just going to let them write this absurd reply … without addressing any of the other concerns,”
  • 200 clinicians and researchers, that calls for the release of Surgisphere’s hospital-level data, an independent validation of the results
  • But the revision had other problems, Chaccour and his colleagues wrote in their blog post. For example, the mortality rate for patients who received mechanical ventilation but no ivermectin was just 21%, which is strikingly low; a recent case series from New York City area found that 88% of COVID-19 patients who needed ventilation died. Also, the data shown in a figure were wildly different from those reported in the text. (Science also attempted to reach Grainger, but received no reply to an email and call.)
  • Surgisphere’s sparse online presence—the website doesn’t list any of its partner hospitals by name or identify its scientific advisory board, for example—have prompted intense skepticism.
  • wondered in a blog post why Surgisphere’s enormous database doesn’t appear to have been used in peer-reviewed research studies until May.
  • how LinkedIn could list only five Surgisphere employees—all but Desai apparently lacking a scientific or medical background—if the company really provides software to hundreds of hospitals to coordinate the collection of sensitive data from electronic health records.
  • Desai’s spokesperson responded to inquiries about the company by saying it has 11 employees and has been developing its database since 2008.
  • The potential of hydroxychloroquine for treating COVID-19 has become a political flashpoint, and the questions around the Lancet paper have provided new fodder to the drug’s supporters. French microbiologist Didier Raoult, whose own widely criticized studies suggested a benefit from the drug, derided the new study in a video posted today, calling the authors “incompetent.” On social media, some speculated that the paper was part of a conspiracy against hydroxychloroquine.
  • Chaccour says both NEJM and The Lancet should have scrutinized the provenance of Surgisphere’s data more closely before publishing the studies. “Here we are in the middle of a pandemic with hundreds of thousands of deaths, and the two most prestigious medical journals have failed us,” he says.
  • Dennis OConnor on 03 Jun 20
     
    Recommended by Mike Kurisu, DO.
Dennis OConnor

Bartonella Babe - YouTube - 0 views

www.youtube.com/...about

media youtube edutainment

shared by Dennis OConnor on 07 Sep 21 - No Cached
  • Dennis OConnor on 07 Sep 21
     
    "Hi everyone! My name is Jake Picker and I make "edutainment" videos about bartonellosis, mast cell activation syndrome (MCAS), SIBO, and other related conditions. Unfortunately, I have been suffering with bartonellosis symptoms for over ten years but became debilitated by those symptoms in August of 2018. Almost every single minute that I feel well enough, I spend researching, writing, filming, and editing my videos for Bartonella Babe. The best way to support me is to shop my Bartonella Babe merch at www.teespring.com/stores/bartonella-babe. I have chosen to donate 25% of all proceeds to the Bartonella Project at the North Carolina State University College of Veterinary Medicine. If you are looking for support, please join our Facebook support group called Breaking Down Bartonella. To stay updated with my life, make sure to subscribe and hit the notification bell. Also, follow me on Instagram @bartonella_babe and on Facebook (Bartonella Babe). Thanks Bartonella buddies!"
Dennis OConnor

HCPs finally embrace the patient-reported-data revolution - Features - MM&M - Medical M... - 1 views

www.mmm-online.com/...tient-reported-data-revolution

tracking data

shared by Dennis OConnor on 16 Oct 20 - No Cached
  • Dennis OConnor on 16 Oct 20
     
    "While Alperin characterizes the shift in support among HCPs as gradual, he points to the arrival of the Apple Watch - the most recent model adds a feature that measures the saturation of oxygen in the user's blood - as "the biggest point of inflection." He notes that he has confirmed the accuracy of the watch's readings against EKGs performed in his office. And while that firsthand experience may be anecdotal, he believes it offers "one more piece of validation.""
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