Effect of fish oil on heart rate in humans: a meta-analysis of randomized controlled trials.
Mozaffarian D, Geelen A, Brouwer IA, Geleijnse JM, Zock PL, Katan MB.
Circulation. 2005 Sep 27;112(13):1945-52. Epub 2005 Sep 19.
PMID: 16172267
doi: 10.1161/CircULATIONAHA.105.556886
Conclusions- In randomized controlled trials in humans, fish oil reduces HR, particularly in those with higher baseline HR or longer treatment duration. These findings provide firm evidence that fish oil consumption directly or indirectly affects cardiac electrophysiology in humans. Potential mechanisms such as effects on the sinus node, ventricular efficiency, or autonomic function deserve further investigation.
Alpha-linolenic acid and risk of nonfatal acute myocardial infarction.
Campos H, Baylin A, Willett WC.
Circulation. 2008 Jul 22;118(4):339-45. Epub 2008 Jul 7. Erratum in: Circulation. 2008 Sep 16;118(12):e492.
PMID: 18606916
doi: 10.1161/CircULATIONAHA.107.762419
Conclusions - Consumption of vegetable oils rich in {alpha}-linolenic acid could confer important cardiovascular protection. The apparent protective effect of {alpha}-linolenic acid is most evident among subjects with low intakes.
Vitamin D deficiency and risk of cardiovascular disease.
Wang TJ, Pencina MJ, Booth SL, Jacques PF, Ingelsson E, Lanier K, Benjamin EJ, D'Agostino RB, Wolf M, Vasan RS.
Circulation. 2008 Jan 29;117(4):503-11. Epub 2008 Jan 7.
PMID: 18180395
doi: 10.1161/CircULATIONAHA.107.706127
Conclusions-Vitamin D deficiency is associated with incident cardiovascular disease. Further clinical and experimental studies may be warranted to determine whether correction of vitamin D deficiency could contribute to the prevention of cardiovascular disease.