Essential fatty acids and their metabolites could function as endogenous HMG-CoA reductase and ACE enzyme inhibitors, anti-arrhythmic, anti-hypertensive, anti-atherosclerotic, anti-inflammatory, cytoprotective, and cardioprotective molecules.\nDas UN.\nLipids Health Dis. 2008 Oct 15;7:37. Review.\nPMID: 18922179 \ndoi:10.1186/1476-511X-7-37
Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease.
Kidd P.
Altern Med Rev. 2003 Aug;8(3):223-46. Review.
PMID: 12946237
Th1 pathways typically produce activation of cytotoxic T
lymphocytes (Tc), NK cells, macrophages, and monocytes, all of
which can attack cancer cells and generally defend against tumors.
55 IFN-gamma and other Th1 cytokines are typically lower in
advanced cancer patients, while the Th2 marker IL-4 can be higher
or unchanged.56 Nodules of non-small cell lung cancer freshly
removed from patients expressed a marked imbalance toward Th2, as
did biopsy samples from basal cell carcinoma.57 In prostate cancer
patients IL-2 was low (Th1) and IL-10 high.58 IL-10 is a confirmed
Th1-suppressive cytokine, and heightened IL-10 is a common factor
in cancer.55
IL-10 has a variety of suppressive effects that include inhibiting
Th1 cytokine production, down-regulating APC and NK cell function,
and lowering overall T-cell proliferation.57 Especially under the
influence of IL-4 (Th2), tumor cells apparently up-regulate IL-10
that suppresses nearby killer cells. Tumor-derived IL-10 has been
documented in lymphoma, ovarian carcinoma, melanoma, neuroblastoma,
and renal cell and colon carcinoma.57 IL-12 is another cytokine
that can be up-regulated by Th1 activity and inhibited by Th2.59 A
low IL-12/IL-10 ratio was found in cervical cancer patients.55
Recent clinical studies suggest elevated IL-10 is predictive of a
poor prognosis. 57 With both IL-4 and IL-10 being proven inhibitors
of Th1 and promoters of Th2 activity, the recognized capability of
cancerous tissue to suppress immunity is readily rationalized.
Vitamin K has been known as the coagulation vitamin, because of its role in the blood-clotting process. However, research over the last few decades has shown that the role of K Vitamins - and natural Vitamin K2, the menaquinones, in particular - has been greatly expanded. Of note, K Vitamins activity outside the liver is required for calcium utilization, the key factor in maintaining both bone and cardiovascular health.\n\nVitamin K2 helps to activate vitamin K-dependent proteins responsible for healthy tissues. In bone, it activates osteocalcin, a protein required to bind calcium to the mineral matrix, thus strengthening the skeleton. In circulation, Vitamin K2 participates in carboxylation of Matrix Gla Protein (MGP), the most potent inhibitor of arterial calcification known, lowering the risk of vascular damage.
WARNING: This page was NOT created or approved by any doctor or medical researcher. The purpose of this page is to provide hard-to-find information on copper reduction cancer treatment, a new unapproved and experimental course of cancer treatment whose ef
Ursolic acid, a natural pentacyclic triterpenoid carboxylic
acid, is the major component of some traditional medicine
herbs and is well known to possess a wide range of
biological functions, such as antioxidative,
anti-inflammatory, antihyperlipidemic and anticancer
activities, that are able to counteract endogenous and
exogenous biological stimuli.
Ursolic acid has been noted for their antitumor-promotion
activities. Ursolic acid is capable of inducing apoptosis in
tumor cells on one side and to prevent malignant
transformation of normal cells on the other side. It also
interferes with numerous enzymes, including the ones
serving directly to DNA synthesis
"ScienceDaily (Jan. 13, 2010) - For those who do not drink, researchers have found that six essential oils -from thyme, clove, rose, eucalyptus, fennel and bergamot -- can suppress the inflammatory COX-2 enzyme, in a manner similar to resveratrol, the chemical linked with the health benefits of red wine. They also identified that the chemical carvacrol was primarily responsible for this suppressive activity."