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Diagnosis and treatment of vitamin D deficiency. Cannell JJ, Hollis BW, Zasloff M, Heaney RP. Expert Opin Pharmacother. 2008 Jan;9(1):107-18. PMID: 18076342 The recent discovery - in a randomised, controlled trial - that daily ingestion of 1100 IU of colecalciferol (vitamin D) over a 4-year period dramatically reduced the incidence of non-skin cancers makes it difficult to overstate the potential medical, social and economic implications of treating vitamin D deficiency. Not only are such deficiencies common, probably the rule, vitamin D deficiency stands implicated in a host of diseases other than cancer. The metabolic product of vitamin D is a potent, pleiotropic, repair and maintenance, secosteroid hormone that targets > 200 human genes in a wide variety of tissues, meaning it has as many mechanisms of action as genes it targets. A common misconception is that government agencies designed present intake recommendations to prevent or treat vitamin D deficiency. They did not. Instead, they are guidelines to prevent particular metabolic bone diseases. Official recommendations were never designed and are not effective in preventing or treating vitamin D deficiency and in no way limit the freedom of the physician - or responsibility - to do so. At this time, assessing serum 25-hydroxy-vitamin D is the only way to make the diagnosis and to assure that treatment is adequate and safe. The authors believe that treatment should be sufficient to maintain levels found in humans living naturally in a sun-rich environment, that is, > 40 ng/ml, year around. Three treatment modalities exist: sunlight, artificial ultraviolet B radiation or supplementation. All treatment modalities have their potential risks and benefits. Benefits of all treatment modalities outweigh potential risks and greatly outweigh the risk of no treatment. As a prolonged 'vitamin D winter', centred on the winter solstice, occurs at many temperate latitudes, ≤ 5000 IU (125 μg) of vitamin D/d

"One of the problems - if it could be called a problem - in writing this blog and moderating the comments is most readers are pretty intelligent. Occasionally I have the angry vegetarian wander in, take me to task for my errant ways, and, after a comeback or two on my part, drift away to never be heard from again. Thanks to the confirmation bias, this blog pretty much selects against the non-meat eater. So, I tend to forget how many people there are out there who are pretty much clueless about basic nutrition, and how many people there are who bobble through life spouting cliches they've heard along the way as great nutritional truths. Based on the comments I get on this blog, it seems to me that most people are pretty nutritionally sophisticated and reasonable."

"The coconut is called the tree of life for it has been providing us, humans, food and drink, materials for housing, fuel and many industrial uses. And its medicinal uses are many and varied. The latest medical potential of products of the coconut first identified by Jon Kabara and others in the 70s, is the anti-bacterial, anti-viral and anti-fungal activity of its medium chain fatty acids, particularly lauric acid (C12:0) in its monoglyceride form (monolaurin or ML). The first clinical trial ever of ML was on 15 HIV-infected patients reporting regularly at the San Lazaro Hospital, Manila who, never having received any anti-HIV medication, were randomly assigned to 3 treatment groups: 7.2 g ML, 2.4 g ML and 50 ML of coconut oil daily for 6 months. The San Lazaro Hospital Team was led by Eric Tayag."

n-3 fatty acids and gene expression. Deckelbaum RJ, Worgall TS, Seo T. Am J Clin Nutr. 2006 Jun;83(6 Suppl):1520S-1525S. Review. Erratum in: Am J Clin Nutr. 2006 Oct;84(4):949. PMID: 16841862 Accumulating evidence in both humans and animal models clearly indicates that a group of very-long-chain polyunsaturated fatty acids, the n-3 fatty acids (or omega-3), have distinct and important bioactive properties compared with other groups of fatty acids. n-3 Fatty acids are known to reduce many risk factors associated with several diseases, such as cardiovascular diseases, diabetes, and cancer. The mechanisms whereby n-3 fatty acids affect gene expression are complex and involve multiple processes. As examples, n-3 fatty acids regulate 2 groups of transcription factors, such as sterol-regulatory-element binding proteins and peroxisome proliferator-activated receptors, that are critical for modulating the expression of genes controlling both systemic and tissue-specific lipid homeostasis. Modulation of specific genes by n-3 fatty acids and cross-talk between these genes are responsible for many effects of n-3 fatty acids.

"The US Food and Drug Administration has advised consumers that certain vitamin supplements "can be useful", stating that "there are many good reasons" to consider taking them. The consumer advisory, released this week in video and text format, comes at a time of increased pressure on the supplements industry, with media outlets repeatedly questioning the usefulness and safety of dietary supplements. "Supplements can be useful when they fulfill a specific identified nutrient need that can't be met by food or is not being met through normal food intake," said Barbara Schneeman, PhD, director of FDA's Office of Nutritional Products, Labeling, and Dietary Supplements. The message is one that dietary supplement trade groups have consistently tried to get across, with campaigns such as CRN's Life…supplemented set up to communicate the importan Vitamins for the right reasons According to FDA's consumer update - Fortify Your Knowledge About Vitamins - there are many good reasons to consider taking vitamin supplements, which could be recommended by a doctor in a number of situations, including: * For certain health problems * When following a vegetarian or vegan diet * When pregnant or breastfeeding Iron and folic acid are important for pregnant women or women of childbearing age, to be consumed via a varied diet or from fortified foods and supplements, says FDA. People over 50 should consume vitamin B12, and those with darker skin or with insufficient exposure to sunlight should consume extra vitamin D, again via fortified foods or supplements."

Male baldness affects approximately every 3 out of 5 men aged between 25 and 35 Many healings in search of male hair loss help them to grow hair, but have found no results. Some very popular hair loss products are out there encouraging regrowth of hair, but often fail. Together with this disorder to treat hair loss, leave these products with many undesirable side effects.

Many people usually neglect the importance of ensuring the need to take good care of their skin, however, many also are not aware that there are simple and effective proper skin care for everyone and anyone.

Plums can be yellow, red, dark red, blue or purple. The inside flesh is succulent plums, but not some other kind of watery. The inside of the yellow or red plums. Some plums have a sweet taste, while others are tart. Many varieties of plums are scattered throughout the world, including in Japan, Europe, Santa Rosa. European Plum smaller size, while no water is Japanese plum.

"One of the problems - if it could be called a problem - in writing this blog and moderating the comments is most readers are pretty intelligent. Occasionally I have the angry vegetarian wander in, take me to task for my errant ways, and, after a comeback or two on my part, drift away to never be heard from again. Thanks to the confirmation bias, this blog pretty much selects against the non-meat eater. So, I tend to forget how many people there are out there who are pretty much clueless about basic nutrition, and how many people there are who bobble through life spouting cliches they've heard along the way as great nutritional truths. Based on the comments I get on this blog, it seems to me that most people are pretty nutritionally sophisticated and reasonable."

"A new study suggests many Americans aren't getting anywhere nearly enough of the vitamin, and it may be affecting their heart health. In the study, researchers looked at tens of thousands of healthy adults 50 and older whose vitamin D levels had been measured during routine checkups. A majority, they found, were deficient in the vitamin. About two-thirds had less vitamin D in their bloodstreams than the authors considered healthy, and many were extremely deficient. Less than two years later, the researchers found, those who had extremely low levels of the vitamin were almost twice as likely to have died or suffered a stroke than those with adequate amounts. They also had more coronary artery disease and were twice as likely to have developed heart failure. The findings, which are being presented today at an American Heart Association conference in Orlando, don't prove that lack of vitamin D causes heart disease; they only suggest a link between the two. "

"In 1995 my son received the devastating diagnosis of MS. Having been a research scientist for 30 years, I decided to plunge into the scientific literature for MS to determine the most likely factors which cause MS and to use this information to develop an effective therapy for my son. Notably, many people are having great success in halting or greatly slowing MS with nutritional strategies; many Testimonials are available. I am most pleased to report that my son remains in excellent health with no MS symptoms. I discovered abundant scientific evidence that indicates that various nutritional factors potentially play major roles in the onset and progression of MS. Strangely, this information was not being made available to persons with MS by doctors nor by established MS charities."

"Cathelicidin antimicrobial peptide is a family of polypeptides found in lysosomes in polymorphonuclear leukocytes (PMNs).[1] Members of the cathelicidin family of antimicrobial polypeptides are characterized by a highly conserved region (cathelin domain) and a highly variable cathelicidin peptide domain. Cathelicidin peptides have been isolated from many different species of mammals. Cathelicidins were originally found in neutrophils but have since been found in many other cells including epithelial cells and macrophages activated by bacteria, viruses, fungi, or the hormone 1,25-D"

The effect of omega-3 FAs on tumour angiogenesis and their therapeutic potential. Spencer L, Mann C, Metcalfe M, Webb M, Pollard C, Spencer D, Berry D, Steward W, Dennison A. Eur J Cancer. 2009 Aug;45(12):2077-86. Epub 2009 Jun 1. Review. PMID: 19493674 Omega-3 fatty acid (omega-3 FA) consumption has long been associated with a lower incidence of colon, breast and prostate cancers in many human populations. Human trials have demonstrated omega-3 FA to have profound anti-inflammatory effects in those with cancer. In vitro and small animal studies have yielded a strong body of evidence establishing omega-3 FA as having anti-inflammatory, anti-apoptotic, anti-proliferative and anti-angiogenic effects. This review explores the evidence and the mechanisms by which omega-3 FA may act as angiogenesis inhibitors and identifies opportunities for original research trialling omega-3 FAs as anti-cancer agents in humans. The conclusions drawn from this review suggest that omega-3 FAs in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) found principally in oily fish have potent anti-angiogenic effects inhibiting production of many important angiogenic mediators namely; Vascular Endothelial Growth Factor (VEGF), Platelet-Derived Growth Factor (PDGF), Platelet-Derived Endothelial Cell Growth Factor (PDECGF), cyclo-oxygenase 2 (COX-2), prostaglandin-E2 (PGE2), nitric oxide, Nuclear Factor Kappa Beta (NFKB), matrix metalloproteinases and beta-catenin

"As more and more research is carried out into foods and the nutrients that they contain, we are seeing that many of the foods we have been eating for generations, and some that are newer to us, are packed full of vitamins and minerals, and many other nutrients with exciting health benefits. This list is provided for your information and reference, however it must be remembered that everybody is unique and has individual nutritional needs, and we recommend seeing a practitioner before making any significant changes to your diet."

"The brain, like most other internal organs, or offal, can serve as nourishment. Brains used for nourishment include those of pigs, squirrels, horses, cattle, monkeys, chickens and goats. In many cultures, different types of brain are considered a delicacy. In the Southern United States, canned pork brain in gravy can be purchased for consumption as food. This form of brain is often fried with scrambled eggs to produce "Eggs n' Brains".[1] They are part of the menu in many family owned restaurants throughout the region. The brain of animals also features in French cuisine, in dishes such as cervelle de veau and tête de veau."

There are many kinds of water. Steam and ice are 2 extremes. Water used to drink is liquid. Liquid water can be affected greatly by the way it is obtained. Distilled water is usually clear of toxins but is also devoid of minerals. Municipally treated water is not too risky from a microbial perspective but contains chlorine and possibly other water treatment and sewage contaminants. Municipal water treatment systems do not remove other waste water contaminants such as excreted drugs, metals, pesticides, insecticides, etc. This is why municipal systems that use deep artesian water are the safest. The best water is obtained from deep artesian wells, uncontaminated by human agency or biologic accidents, where it has filtered through many layers of stone, earth and rocks. The rain water you may drink is very much like distilled water, except it carries with it whatever contaminants are in the atmosphere.

Mango is useful fruit for pregnant women as it contain good amount of iron that enables to maintain the HB level and proper oxygen flow. It is suggested that problems during menstruation. Mango relaxes the muscles and prevent abortion due to presence of calcium and magnesium.

Beneficial in pregnancy of the Mango shakes are having important health benefits during pregnancy due to presence of iron both in milk and mango. Iron is an important mineral required during pregnancy.

Mango is considered to have a rather beneficial effect on the baby's growth patterns. Mango juice for pregnancy is a delightful option. The fact that it has a low calorie count along with significant resources of vitamin C, fiber and vitamin A, it only serves to help increase the speed of the child's physical and mental development. Moreover, the beta carotene content within the fruit means that it significantly helps prevent the development of heart disease in both the mother as well as the child.

A pregnant woman should eat at least one mango a day - the calcium and magnesium of the mango relaxes the muscles, relieves stress and prevents abortion.Mango is a tropical tree cultivated in many regions of India and now distributed wide across the world in many continents. Usually, fruits grow at the end of a long, string like stem, with sometimes more than one fruit to a stem.

Fruit Juice Leading Exporter and Distributor from Indore and Bhopal, Our products are available in a wide range of flavours and pack sizes, such as Mango Juice, Litchi Juice, Nimbu Juice, Sqeeze Mango Juice, PET Bottle Mango Juice, PET Bottle Nimbu Juice (Lemon Drink), PET Bottles Litchi Juice and many more items. All our products are made with real fruit juice or pulp. Mango Pulp used for making the drinks is made from choicest mangoes brought from South India which is the World's largest producer of Mangoes. Our assortment of juicy mango and other drinks offer essential minerals, antioxidants, fiber and vitamin A and C, and is an excellent way of repletion of lost potassium. With the help of professionals, we are capable in offering a wide range of Fruit Juice. Our offered product is processed under hygienic and pure conditions. Regular consumption of our product helps to improve energy level. Apart from this, our product is processed under the guidance of our skilled professionals keeping in mind set industry norms. We have several flavors of juice, which includes mango, litchi, Nimbu etc. Apart from this, clients can avail this product from us at a reasonable price. Features: Freshness Mouth watering taste Rich in minerals Mango Juice We are involved in the distribution, import and export of high-quality Mango Juice and Mango Drinks to our clients. Made using the best quality Mangoes, this juice is rich in nutritional content and contains no preservatives or added flavors. It is completely natural. This product is in compliance with the latest food hygiene and safety norms and is tested for its quality by certified professionals. The juice is packaged efficiently by us to retain the nutritional contents and is delivered in a timely manner through various shipment and transport modes. Features: Timely delivery and export Made from best quality Mangoes Rich nutrient content 100% natural Preservative-free Litchi Juice We distri

Litchi is a fruit with amazing health benefits belongs to Sapindaceae family. It is grown in the tropical and subtropical regions of the world and found abundantly in the summer season. It was first originated in the Chinese regions of Guangdong and Fujian and has been started cultivating in the various countries of the world (India, Vietnam, Sri Lanka, Thailand, Taiwan, Japan, Bangladesh, Nepal, Australia, Pakistan, Malaysia, Vietnam, Mexico, Southern Africa and etc). It is very delicate and attractive smelling fruit which is usually eaten fresh. It is found in many types such as emperor lychee or biggest lychee, ohia lychee or litchi with little seed, Brewster lychee and etc. Benefits of Litchi (Lychee) Fruit Juice It is loaded with numerous healthy nutrients including vitamins, minerals, antioxidants, fatty acids and so many. It protects from various diseases, infections and skin problems by enhancing the immunity power. It contains polyphenols which helps in fighting with weight problems, liver damage and type-2 diabetes. Some of its amazing health benefits are mentioned below: Benefits of Litchi for Heart Benefits of Litchi for Cancer Benefits of Litchi for Digestive System Benefits of Litchi for Bones, Teeth and Joints Benefits of Litchi for Hair Benefits of Litchi for Weight Loss Benefits of Litchi for Aging Benefits of Litchi for Women during Pregnancy Benefits of Litchi for Kids Benefits of Litchi for Men Benefits of Litchi Seeds Benefits of Litchi Juice of Skin Nutrition Facts of Litchi Dash per 100 ml Energy: 60 Kcal Fat: 0 gm Carbohydrate: 14.8 gm Protein: 0 gm Sugar: 12.5 g Vitamins Thiamine: 0.011 mg Riboflavin: 0.065 mg Niacin: 0.603 mg Choline: 7.1 mg Pyridoxine: 0.100 mg Folates: 14 µg Vitamin C: 71.5 mg Vitamin E: 0.07 mg Vitamin K: 0.4 µg Minerals Calcium: 5 mg Copper: 0.148 mg Iron: 0.31 mg Magnesium: 10 mg Manganese: 0.055 mg Phosphorus: 31 mg Selenium: 0.6 µg Zinc: 0.07 mg

Mangoes may very well be the king of all fruits. They Prevents Cancer, alkalize the body, aid in weight loss, regulate diabetes, help digestion, clean your skin, and make the perfect snack. and many reasons why you should be Drinking a mango juice every day. They are Many reasons of mango juice 1. Prevents Cancer Antioxidants like quercetin, isoquercitrin, astragalin, fisetin, gallic acid and methylgallat present in mango protect the body against colon, breast, leukemia and prostate cancers. 2. Helps in Lowering Cholesterol Mango has high level of vitamin C, pectin and fibres that help to lower serum cholesterol levels. Fresh mango is a rich source of potassium, which is an important component of cell and body fluids that helps to control heart rate and blood pressure. 3. Mangoes Nourishes Skin Mango is beneficial for skin health. It is a source of antioxidants which delays the onset of skin aging and pigmentation. Vitamin-C in mango helps in curing pimples and acne. It can be directly applied on the skin as it smoothens it and acts as a natural moisturizer. Antioxidants are responsible to protect against harmful free radicals which can cause skin cancer. Vitamin-A and beta carotene helps in rejuvenating the skin and brings glow to the skin. 4. Alkalizes the body According to natural health, mango juice is rich in tartaric acid, malic acid and traces of citric acid that primarily help in maintaining the alkali reserve of the body. 5. Weight loss Mango has a lot of vitamins and nutrients that help the body feel fuller. Also, the fibrous fruit boosts the digestive function of the body by burning additional calories, helping in weight loss. 6. Regulates diabetes Mango Juice Not only the fruit Juice but the leaves of mangoes are healthy too. For people suffering from diabetes, just boil 5-6 mango leaves in a vessel, soak it through night and drink the filtered decoction in the morning. This is helps in regulating your insulin levels. 7. Ap