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Sean Nash

What Exactly Is 'New Car Smell'? - 0 views

www.mentalfloss.com/...what-exactly-new-car-smell

HSR-2023 HSR science VOCs environmental questions potential research idea chemistry car smell

shared by Sean Nash on 04 Feb 24 - No Cached
  • Sean Nash on 04 Feb 24
     
    I feel like this could form the basis of a student project if we could find a way to measure the VOCs inside the cabin of vehicles and get a dealership or two to give us access.
Sean Nash

Camouflaging wheat with a wheat smell could be a new approach to pest control - 1 views

www.sciencenews.org/...aging-wheat-smell-pest-control

potential research idea biology science HSR HSR-2023 sensing research SCI-I olfactory agriculture farming

shared by Sean Nash on 15 Jun 23 - No Cached
  • Sean Nash on 15 Jun 23
     
    This is a simple concept I wanted to toss out there. A sort of "drowning sensory input" in order to "make finding less effective" sort of approach. I wonder if there are other things this concept might be applied to?
katherine-medina

Topical pine tar: History, properties and use as a treatment for common skin conditions... - 0 views

www.ncbi.nlm.nih.gov/...PMC5434829

pine-tar non-cancerous treatment HSR2023 environmental coal-tar trees wood

shared by katherine-medina on 28 Jul 23 - No Cached
  • Pine tar is thought to exert its effect by reducing DNA synthesis and mitotic activity, which promotes a return to normal keratinisation. In addition, pine tar has been shown to be antipruritic, anti‐inflammatory, antibacterial and antifungal
  • Topical pine tar has been available over‐the‐counter in Australia since 1953. Today, it is available in various formulations including a gel, lotion, oil, soap‐free bar and solution containing up to 2.3% w/w pine tar
  • There are two kinds of wood tars; made either from trees with a high content of resin (pine and juniper), or from hardwood trees (birch and beech).3 Pine tar (also known as tar, alquitrán vegetal, pix liquida, stockholm tar (in commerce), wood tar, brea de pino, brea vegetal, goudron végétal, nadelholzteer, pix abietinarum, pix pini and pyroleum pini
  • ...31 more annotations...
  • There are two kinds of wood tars; made either from trees with a high content of resin (pine and juniper), or from hardwood trees (birch and beech).3 Pine tar (also known as tar, alquitrán vegetal, pix liquida, stockholm tar (in commerce), wood tar, brea de pino, brea vegetal, goudron végétal, nadelholzteer, pix abietinarum, pix pini and pyroleum pini
  • is obtained by high temperature carbonisation of pine wood from various trees of the family Pinaceae in anoxic conditions (dry distillation or destructive distillation)
  • is obtained by high temperature carbonisation of pine wood from various trees of the family Pinaceae in anoxic conditions (dry distillation or destructive distillation)
  • empyreumatic
    • katherine-medina
      katherine-medina on 28 Jul 23
       
      smokey or burnt odor
    • katherine-medina
      katherine-medina on 28 Jul 23
       
      smokey or burnt odor
  • empyreumatic
  • Although pine tar has been used for the treatment of various skin diseases for thousands of years, its mechanism of action is poorly understood and has been extrapolated from studies performed using coal tar.
    • katherine-medina
      katherine-medina on 28 Jul 23
       
      Why is it hard to understand the mechanisms behind how pine tar works?
  • This promotes a return to normal keratinisation, which is important in skin diseases such as psoriasis
    • katherine-medina
      katherine-medina on 28 Jul 23
       
      No kidding.
  • carcinogenic
    • katherine-medina
      katherine-medina on 28 Jul 23
       
      Potential to cause cancer
  • antipruritic
    • katherine-medina
      katherine-medina on 28 Jul 23
       
      It can relieve itching
    • katherine-medina
      katherine-medina on 28 Jul 23
       
      It can relieve itching
  • antipruritic
  • Fractionation of pine tar has revealed that the components responsible for its bacteriostatic properties are the resin acids,14 and that acetovanillone, 1,1′,3,3′‐tetraoxo‐2,2′‐bicyclopentyl and its 4‐methyl derivative,
  • Fractionation of pine tar has revealed that the components responsible for its bacteriostatic properties are the resin acids,14 and that acetovanillone, 1,1′,3,3′‐tetraoxo‐2,2′‐bicyclopentyl and its 4‐methyl derivative,
  • as well as another unknown compound,
    • katherine-medina
      katherine-medina on 28 Jul 23
       
      If they know that there is another component that is responsible for how pine tar works, why haven't they found it yet?
  • as well as another unknown compound,
  • proliferation
    • katherine-medina
      katherine-medina on 28 Jul 23
       
      the rapid growth of multiple cells.
  • Sensitivity to pine tar.18 Pre‐existing folliculitis or severe acne are also possible contraindications.19
  • In terms of pharmacokinetics, it has been observed by infrared spectroscopy that pine tar is detectable in the skin 1 h following the topical application of 12% pine tar to the skin, but was undetectable in the skin after 8 h
  • Thus it can reasonably be assumed that pine tar lacks significant carcinogenic activity.23 Further, pine tar used in the manufacture of topical pine tar products available in Australia today has been found not to be carcinogenic by the Ames test (unpublished data, Ego Pharmaceuticals), and is not classified as a carcinogen
  • Thus it can reasonably be assumed that pine tar lacks significant carcinogenic activity.23 Further, pine tar used in the manufacture of topical pine tar products available in Australia today has been found not to be carcinogenic by the Ames test (unpublished data, Ego Pharmaceuticals), and is not classified as a carcinogen
  • Despite the extensive use of medicinal tars, particularly in psoriasis patients, there is no epidemiological evidence that topical tar products, including pine tar, cause cutaneous or internal cancer
  • Despite the extensive use of medicinal tars, particularly in psoriasis patients, there is no epidemiological evidence that topical tar products, including pine tar, cause cutaneous or internal cancer
  • Hypersensitivity reactions for tars are rare, but wood tars are more likely to cause sensitisation than coal tar
  • Hypersensitivity reactions for tars are rare, but wood tars are more likely to cause sensitisation than coal tar
  • It is important to note that the number of positive reactions for wood tars was not significantly greater than those for other common allergens.
  • It is important to note that the number of positive reactions for wood tars was not significantly greater than those for other common allergens.
  • generally a mixture of pine, juniper, birch and beech tars, and therefore the exact tar eliciting the positive reaction is not known.
  • Furthermore, there have been only five cases of adverse events for pine tar reported to the Therapeutic Goods Administration of Australia since records began in 1971, which included pruritus, rash and dermatitis.
  • Of the 21 patients 19 preferred the pine tar baths due to the attractive green colour and smell
  • pityrosporum
    • katherine-medina
      katherine-medina on 28 Jul 23
       
      A yeast that is associated with dandruff aka ovale
    • katherine-medina
      katherine-medina on 28 Jul 23
       
      A yeast that is associated with dandruff aka ovale
  • Both pine tar and glucocorticosteroid treatments had an almost equally inhibiting effect on the various cellular constituents of allergic inflammation including the influx of T‐cells, eosinophils, and CD1+, RFD1+, IFN‐γ+, and IL‐4+ cells,
  • Both pine tar and glucocorticosteroid treatments had an almost equally inhibiting effect on the various cellular constituents of allergic inflammation including the influx of T‐cells, eosinophils, and CD1+, RFD1+, IFN‐γ+, and IL‐4+ cells,
  • katherine-medina on 28 Jul 23
     
    A nice summary about what pine tars are and what they can do.
Sean Nash

Microwaving an insecticide restores its mosquito-killing power - 2 views

www.sciencenews.org/...to-microwave-insecticide-spray

deltamethrin pesticide mosquito insecticide DDT crystals crystalline structure biochemistry environment evolution ecology chemistry heat potential research idea biology engineering environmental science HSR HSR-2023 HSR-2025

shared by Sean Nash on 25 May 23 - No Cached
  • Heating an insecticide can give it new life.
    • Sean Nash
      Sean Nash on 25 May 23
       
      Wait, what? Do say more.....
  • Microwaving the insecticide deltamethrin rearranges its crystal structure but doesn’t change its chemical composition. The rearrangement renews deltamethrin’s ability to kill mosquitoes that have become resistant to the insecticide, researchers report April 21 in Malaria Journal.
    • Sean Nash
      Sean Nash on 25 May 23
       
      Hmmmm... something similar to this smells like: feasibility.
  • The microwave worked just as well, but Kahr cautions that people shouldn’t use the same microwave for heating food and insecticides.
    • Sean Nash
      Sean Nash on 25 May 23
       
      Ha! No kidding??
  • ...6 more annotations...
  • insecticide resistance is a growing problem
  • It is encouraging that heated insecticide killed highly resistant mosquitoes, says Hemingway, who directs the Infection Innovation Consortium, a public-private effort to find new ways to combat infectious diseases. But, she says, “this is not something we can take and use that tomorrow.”
    • Sean Nash
      Sean Nash on 25 May 23
       
      OK.... this is how you can find an opening (not saying THIS ONE is necessarily, but, when you see language like: "we can't really do it just yet," that is a screaming opportunity to see what we MIGHT be able to add to that.
  • It’s not certain that the heat-treated deltamethrin would retain its more potent crystal structure through the net-making process.
  • Kahr’s team is working on incorporating the heat-treated crystal into nets.
  • “There are all kinds of social and cultural things that you could propose from a scientific perspective that wouldn’t be welcomed by a community of homeowners.”
    • Sean Nash
      Sean Nash on 25 May 23
       
      Again... this reads: "potential research opportunity."
  • Kahr and colleagues previously discovered that heating deltamethrin changed its crystal structure, which let it work faster
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