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Matti Narkia

Omega fatty acid balance can alter immunity and gene expression - 0 views

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    Floyd Chilton and colleagues wanted to examine whether theses fatty acids might have other effects, and developed a dietary intervention strategy in which 27 healthy humans were fed a controlled diet mimicking the w6/w3 ratios of early humans over 5 weeks. They then looked at the gene levels of immune signals and cytokines (protein immune messengers), that impact autoimmunity and allergy in blood cells and found that many key signaling genes that promote inflammation were markedly reduced compared to a normal diet, including a signaling gene for a protein called PI3K, a critical early step in autoimmune and allergic inflammation responses. This study demonstrates, for the first time in humans, that large changes in gene expression are likely an important mechanism by which these omega fatty acids exert their potent clinical effects
Matti Narkia

Genetically Altered Mice Stay Lean With High-Carb Diet - 0 views

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    Researchers at the University of California, Berkeley, have identified a gene that plays a critical regulatory role in the process of converting dietary carbohydrates to fat. In a new study, they disabled this gene in mice, which consequently had lower levels of body fat than their normal counterparts, despite being fed the equivalent of an all-you-can-eat pasta buffet. The authors of the study, to be published in the March 20 issue of the journal Cell, say the gene, called DNA-PK, could potentially play a role in the prevention of obesity related to the over-consumption of high-carbohydrate foods, such as pasta, rice, soda and sugary snacks.
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Vitamin D, a Gene-Regulating Super-Nutrient - 0 views

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    Your cells use vitamin D to directly regulate your genes, making it one of the most powerful compounds in human health.
Matti Narkia

Fish oil feeding alters liver gene expressions to defend against PPARalpha activation ... - 0 views

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    These data indicate that fish oil feeding downregulated the endogenous PPAR-activation system and increased antioxidant gene expressions to protect against ROS excess Fish oil feeding alters liver gene expressions to defend against PPARalpha activation and ROS production. Takahashi M, Tsuboyama-Kasaoka N, Nakatani T, Ishii M, Tsutsumi S, Aburatani H, Ezaki O. Am J Physiol Gastrointest Liver Physiol. 2002 Feb;282(2):G338-48. PMID: 11804856
Matti Narkia

Multiple Sclerosis Caused by Vitamin D Deficiency - 0 views

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    NaturalNews) Researchers from Oxford University and the University of British Columbia have discovered that Vitamin D deficiency affects a section of the human genome already linked with multiple sclerosis (MS) risk, adding further weight to theories that this vitamin deficiency might play a role in development of the disease. "Here we show that the main environmental risk candidate -- vitamin D -- and the main gene region are directly linked and interact," said co-author George Ebers.
Matti Narkia

Fish oil and treatment of cancer cachexia - Genes Nutr. 2008 Apr. - 0 views

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    Fish oil and treatment of cancer cachexia. Giacosa A, Rondanelli M. Genes Nutr. 2008 Apr;3(1):25-8. PMID: 18850196
Matti Narkia

Lack of sunshine found to trigger multiple sclerosis | Society | guardian.co.uk - 0 views

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    Research finds people with gene variant who lack vitamin D, produced from sun exposure, can develop condition
Matti Narkia

Fish Oil Consumption and Reduction of Arterial Disease -- Vanschoonbeek et al. 133 (3):... - 0 views

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    Here we propose that the beneficial effect of (n-3) PUFA diet is related to down-regulation of the mutually positive interactions of platelet activation and coagulation. In addition, we consider the possibility that the dietary effect on hemostatic and lipid factors involves transcription regulation of multiple genes, perhaps in a subject-dependent manner. Fish oil consumption and reduction of arterial disease. Vanschoonbeek K, de Maat MP, Heemskerk JW. J Nutr. 2003 Mar;133(3):657-60. Review. PMID: 12612132
Matti Narkia

Sham vs. Wham: The Health Insider: Omega 3 In the News Again - Lower Advanced Prostate ... - 0 views

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    new (March 24th) report in Clinical Cancer Research, a journal of the American Association for Cancer Research, shows that Omega-3 fatty acids appear protective against advanced prostate cancer. Dr. John S. Witte, Ph.D., professor of epidemiology and biostatistics at the University of California San Francisco, says that previous research has shown protection against prostate cancer, but that this is one of the first studies to show protection against advanced prostate cancer.
Matti Narkia

Dietary Omega-3 Fatty Acids, Cyclooxygenase-2 Genetic Variation, and Aggressive Prostat... - 0 views

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    Dietary Omega-3 Fatty Acids, Cyclooxygenase-2 Genetic Variation, and Aggressive Prostate Cancer Risk. Fradet V, Cheng I, Casey G, Witte JS. Clin Cancer Res. 2009 Mar 24. [Epub ahead of print] PMID: 19318492 DOI: 10.1158/1078-0432.CCR-08-2503
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