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Matti Narkia

Vitamin D and Vitamin K Team Up to Lower CVD Risk - Part I - 0 views

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    Strong correlations have been noted between cardiovascular diseases and low bone density / osteoporosis-connections so strong that the presence of one type of pathology is considered a likely predictor of the other. This potentially causal relationship has led to the hypothesis that these conditions share core mechanisms. Recent advances in our understanding of the complimentary roles played by vitamin D3 and vitamin K2 in vascular and bone health provide support for this hypothesis, along with insight into key metabolic dysfunctions underlying cardiovascular disease and osteoporosis. Part I of this review summarizes current research linking vitamin D deficiency to cardiovascular disease, the physiological mechanisms underlying vitamin D's cardiovascular effects, and leading vitamin D researchers' recommendations for significantly higher supplemental doses of the pro-hormone. Part II reviews the vitamin K connection to cardiovascular disease; the ways in which vitamin D and vitamin K pair up to prevent inflammation, vascular calcification and osteoporosis; and the necessity of providing vitamin K along with vitamin D to preclude adverse effects associated with hypervitaminosis D, which include vascular and other soft tissue calcification.
Matti Narkia

Vitamin D and Vitamin K Team Up to Lower CVD Risk - Part II - 0 views

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    Strong correlations have been noted between cardiovascular diseases and low bone density / osteoporosis-connections so strong that the presence of one is considered a likely predictor of the other. This relationship has led to the hypothesis that these conditions share core pathophysiological mechanisms. Recent advances in our understanding of the complimentary roles played by vitamin D3 and vitamin K2 in vascular and bone health provide support for this hypothesis, along with insight into key metabolic dysfunctions underlying cardiovascular disease and osteoporosis. Part II, The Vitamin K Connection to Cardiovascular Health, reviews the ways in which vitamin K regulates calcium utlization, preventing vascular and soft tissue calcification while complimenting the bone-building actions of vitamin D, and also discusses vitamin K safety and dosage issues, and the necessity of providing vitamin K and vitamin A along with vitamin D to preclude adverse effects associated with hypervitaminosis D.
Matti Narkia

Vitamin D - Linus Pauling Institute at Oregon State University - 0 views

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    Vitamin D is a fat-soluble vitamin that is essential for maintaining normal calcium metabolism (1). Vitamin D3 (cholecalciferol) can be synthesized by humans in the skin upon exposure to ultraviolet-B (UVB) radiation from sunlight, or it can be obtained from the diet. Plants synthesize ergosterol, which is converted to vitamin D2 (ergocalciferol) by ultraviolet light. Vitamin D2 is less active in birds than vitamin D3 and may also be less active in humans (2). When exposure to UVB radiation is insufficient for the synthesis of adequate amounts of vitamin D3 in the skin, adequate intake of vitamin D from the diet is essential for health.
Matti Narkia

VitaminK2.org - 0 views

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    Vitamin K has been known as the coagulation vitamin, because of its role in the blood-clotting process. However, research over the last few decades has shown that the role of K Vitamins - and natural Vitamin K2, the menaquinones, in particular - has been greatly expanded. Of note, K Vitamins activity outside the liver is required for calcium utilization, the key factor in maintaining both bone and cardiovascular health.\n\nVitamin K2 helps to activate vitamin K-dependent proteins responsible for healthy tissues. In bone, it activates osteocalcin, a protein required to bind calcium to the mineral matrix, thus strengthening the skeleton. In circulation, Vitamin K2 participates in carboxylation of Matrix Gla Protein (MGP), the most potent inhibitor of arterial calcification known, lowering the risk of vascular damage.
Matti Narkia

The Heart Scan Blog: Vitamin D for Peter, Paul, and Mary - 0 views

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    Why is it that vitamin D deficiency can manifest in so many different ways in different people? One big reason is something called vitamin D receptor (VDR) genotypes, the variation in the receptor for vitamin D. Why is it that the dose of vitamin D necessary to reach a specific level differs so widely from one person to the next? VDR genotype, again. Variation in blood levels of 25-hydroxy vitamin D from a specific dose of vitamin D can vary three-fold, as shown by a University of Toronto study. In other words, a dose of 4000 units per day may yield a 25-hydroxy vitamin D blood level of 30 ng/ml in Mary, 60 ng/ml in Paul, and 90 ng/ml in Pete--same dose, different blood levels.
Matti Narkia

Sulbutiamine : by Ray Sahelian, M.D. - 0 views

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    Sulbutiamine is a centrally acting cholinergic vitamin B analogue. One study shows sulbutiamine improve memory in rats. At this time I prefer using a combination of several B vitamins rather than relying on one vitamin B analogue. For more information on B vitamins or to purchase Vitamin B Coenzyme. Even better is to take a multivitamin that has a combination of the B vitamins along with a couple of dozen vitamins and nutrients. In most cases I think it is better to take a small amount of a number of different nutrients as opposed to a large amount of just one. Consider a very popular product that I have formulated called MultiVit-Rx.
Matti Narkia

Vitamin D delivers multiple benefits | ajc.com - 0 views

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    Vitamin D may not just be good for you, it may help save your life. Recent research from Johns Hopkins University suggests that higher amounts of vitamin D in your diet decreases your likelihood of dying. Studies found that a vitamin D deficiency increases your risk of death by 26 percent, and vitamin D decreases the mortality rate from almost every type of cancer including breast, colon and prostate. Research also suggests that vitamin D helps prevent diabetes, kidney disease and cardiovascular disease.
Matti Narkia

Vitamin K - Linus Pauling Institute at Oregon State University - 0 views

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    Vitamin K is a fat-soluble vitamin. The "K" is derived from the German word "koagulation." Coagulation refers to the process of blood clot formation. Vitamin K is essential for the functioning of several proteins involved in blood clotting (1). There are two naturally occurring forms of vitamin K
Matti Narkia

The Heart Scan Blog: Dr. Reinhold Vieth on vitamin D - 0 views

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    A Track Your Plaque member brough the following webcast to our attention: Prospects for Vitamin D Nutrition\nwhich can be found at http://tinyurl.com/f93vl (The above link no longer seems to work, use http://wildhorse.insinc.com/directms13oct2005/ instead) Despite the painfully dull title, the webcast is the best summary of data on the health benefits on vitamin D that I've seen. The presenter is Dr. Reinhold Vieth, who is among the handful of worldwide authorities on vitamin D. In 1999, Dr. Vieth authored the first review to concisely and persuasively argue that vitamin D nutrition was woefully neglected and that its potential for health was enormous.
Matti Narkia

Vitamin D Newsletter March 2009 | All Things Vitamin D - 0 views

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    This is a very long newsletter. I will answer questions about oil versus water-soluble Vitamin D, depression, mental clarity, malignant melanoma, Crohn's disease, an imagist poet, multiple sclerosis, sun-exposure, high-intensity red light and collagen repair in the skin, non-alcoholic fatty liver disease, influenza, the 1918 influenza pandemic, statins, the new Food and Nutrition Board, thyroid disease, chronic fatigue syndrome, athletes, the upcoming 14th Vitamin D Workshop, prostate cancer, the wrong blood test, pregnancy, autism, Alzheimer's disease, soap and sebum, asthma, sleep, the co-factors vitamin D needs to work (all contained in spinach), and-my favorite-UVC light and Vitamin D
Matti Narkia

Vitamin K2, but not K1, effective for heart health benefits: Study - 0 views

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    Increased intakes of vitamin K2, but not vitamin K1, may decrease the risk of coronary heart disease in postmenopausal women, says a new study.\nFor every 10 microgram increase in the amount of vitamin K2 consumed, researchers from the Netherlands report a 9 per cent reduction in the risk of developing coronary heart disease (CHD).
Dr. John Bureau DC

Vitamin C Stops the Growth of Some Cancerous Tumors in Mice - 0 views

  • (NaturalNews) 30 years ago the famous Nobel laureate Linus Pauling said that vitamin C supplements can prevent cancer, a highly controversial statement at the time. Now a team of Johns Hopkins scientists have shown that vitamin C stops the growth of some tumors in mice.The StudyThe study was lead by Chi Dang, M.D., Ph.D., professor of medicine and oncology and Johns Hopkins Family Professor in Oncology Research. Their work is detailed in Cancer Cell, Volume 12, Issue 3, 230-238, 11 September, 2007. They found that the antioxidants' actual role may be to destabilize a tumor's ability to grow under conditions where there isn't enough oxygen to feed it. The conventional belief is that vitamin C helps prevent cancer growth by grabbing up volatile oxygen free radical molecules and preventing the damage they do to our DNA. "The potential anticancer benefits of antioxidants have been the driving force for many clinical and preclinical studies," Says Dang. "By uncovering the mechanism behind antioxidants, we are now better suited to maximize their therapeutic use."
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    (NaturalNews) 30 years ago the famous Nobel laureate Linus Pauling said that vitamin C supplements can prevent cancer, a highly controversial statement at the time. Now a team of Johns Hopkins scientists have shown that vitamin C stops the growth of some tumors in mice. The Study The study was lead by Chi Dang, M.D., Ph.D., professor of medicine and oncology and Johns Hopkins Family Professor in Oncology Research. Their work is detailed in Cancer Cell, Volume 12, Issue 3, 230-238, 11 September, 2007. They found that the antioxidants' actual role may be to destabilize a tumor's ability to grow under conditions where there isn't enough oxygen to feed it. The conventional belief is that vitamin C helps prevent cancer growth by grabbing up volatile oxygen free radical molecules and preventing the damage they do to our DNA. "The potential anticancer benefits of antioxidants have been the driving force for many clinical and preclinical studies," Says Dang. "By uncovering the mechanism behind antioxidants, we are now better suited to maximize their therapeutic use."
Matti Narkia

Mean Serum 25(OH)D Levels Decreasing in All Categories of the US Population - 0 views

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    March 27, 2009 - A significant decrease in serum 25-hydroxyvitamin D (25[OH]D) levels has led to an increase in vitamin D insufficiency in the US population, especially in racial and ethnic groups, according to results of a population-based study reported in the March 23 issue of the Archives of Internal Medicine. "Vitamin D insufficiency has been associated with increases in cardiovascular disease, cancer, and infection," write Adit A. Ginde, MD, from the Department of Emergency Medicine at the University of Colorado Denver School of Medicine, Aurora, Colorado, and colleagues. "Vitamin D supplementation appears to mitigate the incidence and adverse outcomes of these diseases and may reduce all-cause mortality." [...] "These findings have important implications for health disparities and public health," the study authors conclude. "Our data provide additional evidence that current recommendations for vitamin D supplementation (200-600 IU/d) are inadequate to achieve optimal serum 25(OH)D levels in most of the US population." They add that large, randomized controlled trials of higher doses of vitamin D supplementation are needed to evaluate their effect on general health and mortality.
Matti Narkia

Women With Breast Cancer Have Low Vitamin D Levels - 0 views

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    "ScienceDaily (Oct. 8, 2009) - Women with breast cancer should be given high doses of vitamin D because a majority of them are likely to have low levels of vitamin D, which could contribute to decreased bone mass and greater risk of fractures, according to scientists at the University of Rochester Medical Center." Scientists funded by the NCI analyzed vitamin D levels in each woman, and the average level was 27 nanograms per milliliter; more than two-thirds of the women had vitamin deficiency. Weekly supplementation with high doses of vitamin D -- 50,000 international units or more -- improved the levels, according to Peppone's study. The U.S. Institute of Medicine suggests that blood levels nearing 32 nanograms per milliliter are adequate.
Matti Narkia

Vitamin D Tied To Muscle Power In Adolescent Girls - 0 views

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    ScienceDaily (Feb. 10, 2009) - Vitamin D is significantly associated with muscle power and force in adolescent girls, according to a new study. Although vitamin D is naturally produced in the body through exposure to direct sunlight, vitamin D deficiency has become widely common in the United States. Vitamin D deficiency has been shown to have a significant negative impact on muscle and bone health, and can lead to conditions including osteoporosis and rickets.
Matti Narkia

Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-... - 0 views

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    Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7.\nSchurgers LJ, Teunissen KJ, Hamulyák K, Knapen MH, Vik H, Vermeer C.\nBlood. 2007 Apr 15;109(8):3279-83. Epub 2006 Dec 7.\nPMID: 17158229 \nDOI 10.1182/blood-2006-08-040709\n
Matti Narkia

The antibiotic vitamin: deficiency in vitamin D may predispose people to infection | Sc... - 0 views

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    In the July 2005 FASEB Journal, Adrian F. Gombart of the University of California, Los Angeles (UCLA) and his colleagues reported that vitamin D boosts production in white blood cells of one of the antimicrobial compounds that defends the body against germs.\n\nImmediately, Cannell says, the proverbial lightbulb went on in his head: Maybe the high doses of vitamin D that he had been prescribing to virtually all the men on his ward had boosted their natural arsenal of the antimicrobial, called cathelicidin, and protected them from flu. Cannell had been administering the vitamin D because his patients, like many other people in the industrial world, had shown a deficiency:
Matti Narkia

Vitamin D deficiency linked to more colds and flu: Scientific American Blog - 0 views

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    Is sunshine more than just a home remedy for a cold? New research suggests it may be: In a study that will be published tomorrow, people with low levels of vitamin D - also known as the "sunshine vitamin" - were more likely to catch cold and flu than folks with adequate amounts. The effect of the vitamin was strongest in people with asthma and other lung diseases who are predisposed to respiratory infections.
Matti Narkia

The Healthy Skeptic · Vitamin K2: The Missing Nutrient - 0 views

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    A study recently published by the European Prospective Investigation into Cancer and Nutrition (EPIC) has revealed that increased intake of vitamin K2 may reduce the risk of prostate cancer by 35 percent. The authors point out that the benefits of K2 were most pronounced for advanced prostate cancer, and, importantly, that vitamin K1 did not offer any prostate benefits.
Matti Narkia

Low Vitamin D Levels Linked to Colds - WebMD - 0 views

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    Feb. 23, 2009 -- A walk in the sun may be better than popping a vitamin C tablet for boosting your chances of preventing the common cold or flu.\n\nA new study adds to mounting evidence that vitamin C may have been stealing the spotlight all these years from the real cold fighter, vitamin D.
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