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The National Birth Defects Prevention Network (NBDPN) is a group of individuals involved in birth defects surveillance, research, and prevention. It was created to establish and maintain a national network of state and population-based programs for birth defects surveillance and research. The Network assesses the impact of birth defects upon children, families, and health care; identifies factors that can be used to develop primary prevention strategies; and assists families and their providers in secondary disabilities prevention.

Clinical Trial - Omega-3 Fatty Acid supplementation to Prevent Preterm Birth in High Risk Pregnancies - A recently completed trial of weekly injections of 17 alpha hydroxyprogesterone caproate (17P) found significant effectiveness for 17P in preventing recurrent preterm birth. However, the group who received 17P in this trial still had a high rate of preterm birth. Several reports have shown that dietary supplementation of fish oil, which is rich in Omega-3 fatty acids, reduces the risk of preterm birth. This trial tests whether adding the Omega-3 supplement to 17P therapy has the potential for further reducing the risk of preterm birth in women who have previously had a spontaneous preterm delivery. The trial will compare Omega-3 fatty acid with placebo in women receiving 17P therapy.

Article from The New England Journal of Medicne - offering information on a Randomized, Controlled Trial of Magnesium Sulfate for the Prevention of Cerebral Palsy

A Pilot Study to Assess the Efficacy and Effectiveness of High-Frequency Chest Wall Oscillation (HFCWO) in Preventing Pulmonary Exacerbations in Children With Muscle Weakness and Restrictive Lung Disease To further demonstrate that airway clearance provided by Vest therapy reduces the frequency of respiratory exacerbations requiring hospitalization or antibiotic utilization in patients with muscle weakness and restrictive lung disease.

NICHD - National Institute of Health - Eunice Kennedy Shriver National Institute of Child Health & Human Development - Story of Discovery - Research to Prevent Brain Damage in Newborns

NIH, and Eunice Kennedy Shriver National Institute of Child Health and Human Development - Review and trial to determine whether magnesium sulfate administered to women at risk of preterm delivery may reduce the risk of cerebral palsy in their children

The New England Journal of Medicine Abstract: Can We Prevent Cerebral Palsy, Oct 2003

National Library of Medicine National Institutes of Health PubMed Abstract: Antenatal magnesium sulfate for the prevention of cerebral palsy in preterm infants less than 34 weeks gestation: a systematic reiew and metaanalysis

Centers for Disease Control and Prevention CDC 0 Jaundice / Kernicterus - Did you know that jaundice can sometimes lead to brain damage in newborns? - Prevention - Treatment - coping - Free Materials - Frequently Asked Questions and more.

Plum leads the way in falls safety, protective headgear, hip protectors and extremity guards, so little ones can stay active, adults independent, and caregivers can enjoy peace of mind. Patented protective headgear, hip protectors and extremity guards

The IDD Branch sponsors research and research training aimed at preventing and ameliorating intellectual and related developmental disabilities. The program supports biomedical, biobehavioral, behavioral, and translational research in etiology, pathophysiology, screening, prevention, treatment, and epidemiology.

Study sponsored by Assistance Publique-Hopitaux de Paris investigating Early Prevention of Broncho-pulmonary Dysplasia and Neonatal Mortality in Very Preterm Infants Using Low Dose of Hydrocortisone

Study sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD will evaluate the effects of giving magnesium to premature infants.

Hundreds of babies in the world are being treated with brain cooling to prevent brain injury after they lose oxygen at birth. This study will use the newly developed information from the magnet resonance image to determine the actual temperature of the brain. This will enable researchers to determine if the brain is being uniformly cooled and if techniques that provide cooling need to be changed to improve the injury prevention from cooling

Research/study hypothesis is that topiramate will reduce acute seizures after traumatic brain injury and will help prevent the development of epilepsy after traumatic brain injury.

In large, multicenter clinical studies, a therapy has been shown to significantly lower the risk of lung and brain damage in some very low birthweight premature infants. Results from two randomized clinical trials demonstrate that when given within the first few weeks of life, inhaled nitric oxide helps prevent chronic lung disease in some low birthweight premature infants. In addition, when used within 48 hours after birth, treatment appears to protect some premature newborns from brain injury.

Magnesium Sulfate Study for the Prevention of Cerebral Palsy

CDC - Centers for Disease control and Prevention - Your Online Source for Credible Health Information. The CDC is recognized around the world as a leading force in public health expertise.

CDC Centers for Disease Control and Prevention - Developmental disabilities: Topic Home

University of California - Irvine conducted successful study involving two compounds developed by UC Irvine and Northwestern University scientists that prevented cerebral palsy in preclinical animal trials, giving hope that a new drug for humans may be on the horizon