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NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development - NIH News - Common Treatment to Delay Labor Decreases Preterm Infants' Risk for Cerebral Palsy, August 2008

The Clinical Center at the National Institutes of Health (NIH) in Bethesda, Maryland, is the nation's largest hospital devoted entirely to clinical research. It is a national resource that makes it possible to rapidly translate scientific observations and laboratory discoveries into new approaches for diagnosing, treating, and preventing disease. Approximately 1,500 studies are in progress at the NIH Clinical Center.

In large, multicenter clinical studies, a therapy has been shown to significantly lower the risk of lung and brain damage in some very low birthweight premature infants. Results from two randomized clinical trials demonstrate that when given within the first few weeks of life, inhaled nitric oxide helps prevent chronic lung disease in some low birthweight premature infants. In addition, when used within 48 hours after birth, treatment appears to protect some premature newborns from brain injury.

NINDS National Institute of Neurological Disorders and Stroke. The mission of the National Institute of Neurological Disorders and Stroke is to reduce the burden of neurological disease - a burden borne by every age group, by every segment of society, by people all over the world. Disorders A-Z, News, Research, Health Information, Clinical Trial News and Opportunieis, Information and Resources

NIH Medline Plus - Low Umbilical Cord pH Tied to Death, Brain Damage

National Institute of Health NIH, National Library of Medicine PubMed article Abstract: Defining cerebral palsy: pathogenesis, pathophysiology and new intervention. The focus of this paper is to explore antenatal antecedents as etiologies of CP and the impact of obstetric care on the prevention of CP.

NINDS - what's Old is New Again - Antibiotic Protects Nerves By Removing Excess Glutamate

Information and news on study funded by National Institute of Neurological Disorders and Stroke (NINDS) helps explain why newborn brain responds differently to anticonvulsant medications.

NINDS - Researchers Identify a Signal for Cell Death during Stroke - In a new study, researchers have identified a signal that promotes the death of vulnerable brain cells in an animal model of stroke. In the future, drugs designed to inhibit this death signal might help reduce brain damage in stroke patients

NICHD - National Institute of Health - Eunice Kennedy Shriver National Institute of Child Health & Human Development - Story of Discovery - Research to Prevent Brain Damage in Newborns

In the new study, researchers led by Maiken Nedergaard, M.D., D.MSc., of the University of Rochester , showed that glutamate produced by astrocytes can trigger seizures.

2009 School of Medicine, University of Mostar, Bosnia and Herzegovina Study to investigate the risk factors associated with Cerebral Palsy

PubMed Abstract of observations that concluded that significant improvements were noted when comparing the two-electrode system with the new multiple level electrode. Marked to moderately improved patients increased from 57 to 84% in Cerebral Palsy, from 44 to 82% in dystonia, from 53 to 75% in torticollis and from 53 to 80% in Cystonia, from 53 to 80% in posttraumatic neurologic conditions

Government sponsored effort designed to provide early incentives that encourage and facilitate the discovery of new therapeutic agency.

The first comprehensive comparative effectiveness clinical trial of three widely used anti-seizure drugs for childhood absence epilepsy - the most common form of epilepsy in kids - has established an evidence-based approach for initial drug therapy. Published March 4 in the New England Journal of Medicine*, data from the double-blind, randomized, comparative clinical trial fill a large information gap in the treatment of childhood absence epilepsy, also known as "petit mal" epilepsy. The research, which identifies important differences between drugs in seizure control and side effects, is expected to impact how physicians select and monitor initial therapy for children with the disorder and ultimately lead to improved outcomes.

A service of the U.S. National Library of Medicine and the National Institutes of Health. MedlinePlus will direct you to information to help answer health questions. MedlinePlus brings together authoritative information from NLM, the National Institutes of Health (NIH), and other government agencies and health-related organizations. Preformulated MEDLINE searches are included in MedlinePlus and give easy access to medical journal articles. MedlinePlus also has extensive information about drugs, an illustrated medical encyclopedia, interactive patient tutorials, and latest health news.