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In large, multicenter clinical studies, a therapy has been shown to significantly lower the risk of lung and brain damage in some very low birthweight premature infants. Results from two randomized clinical trials demonstrate that when given within the first few weeks of life, inhaled nitric oxide helps prevent chronic lung disease in some low birthweight premature infants. In addition, when used within 48 hours after birth, treatment appears to protect some premature newborns from brain injury.

Study to determine if Inhaled Nitric Oxide (iNO) given into an oxygen hood is effective in improving oxygenation in term and near-term infants who have poor oxygenation but who are not yet mechanically ventilated.

University of California - Irvine conducted successful study involving two compounds developed by UC Irvine and Northwestern University scientists that prevented cerebral palsy in preclinical animal trials, giving hope that a new drug for humans may be on the horizon