Group items tagged

Observational cohort study designed to identify the mechanisms of disease in patients with preterm labor/contractions and preterm premature rupture of membranes and to describe the relationship between clinical, biochemical, histological, biophysical parameters and the development of infant neurological disorders.

Future planned study to assess the effect of the Protein Composition on the Gastric Emptying Rate in Children With Cerebral Paresis and find out whether 4 different protein sources affect the rate of gastric emptying and electrofysiology in children with cerebral palsy

A Pilot Study to Assess the Efficacy and Effectiveness of High-Frequency Chest Wall Oscillation (HFCWO) in Preventing Pulmonary Exacerbations in Children With Muscle Weakness and Restrictive Lung Disease To further demonstrate that airway clearance provided by Vest therapy reduces the frequency of respiratory exacerbations requiring hospitalization or antibiotic utilization in patients with muscle weakness and restrictive lung disease.

Study will measure the frequency of several coagulation factor abnormalities (factor V Leiden, prothrombin 20210A, protein C, protein S, antithrombin III, and antiphospholipid antibodies) in children with a history of porencephaly and stroke, and will compare these to the prevalence of these mutations in population controls and family members.

London study to determine if acupuncture helps delayed gastric emptying

European study to find out whether 4 different protein sources affect the rate of gastric emptying and electrofysiology in this group of children.The protein composition of nutrition may affect the rate of gastric emptying and gastric fysiology. This is especially important in children with neurologic impariment, who commonly rely on tube feedings, have feeding problems, nausea, vomiting, gastroesophageal reflux and delayed gastric emptying.

Abstract - CONTEXT: Chorioamnionitis has been implicated in the pathogenesis of cerebral palsy, but most studies have not reported a significant association. Cystic periventricular leukomalacia (cPVL) is believed to be a precursor of cerebral palsy in preterm infants. OBJECTIVES of the study is to determine whether chorioamnionitis is associated with cerebral palsy or cPVL and to examine factors that may explain differences in study results.

Italian sponsored and NIH PubMed published abstract of study in the role of foetal lactate in the prevention of cerebral palsy during labor

New England Journal of Medicine abstract of study to evaluate the effects of induction of moderate hypothermia in infants who had perinatal asphyxia. Study concluded that Induction of moderate hypothermia for 72 hours in infants who had perinatal asphyxia did not significantly reduce the combined rate of death or severe disability but resulted in improved neurologic outcomes in survivors. (Current Controlled Trials number, ISRCTN89547571 [controlled-trials.com] .)

National Institute of Neurological Disorders and Stroke (NINDS) Cerebral Hypoxia Information Page

NIH Clinical Study - This multi-center collaborative study will establish a database of information about stroke in infants and children

Office of Special Education and Rehabilitative Services (OSERS) Communication and Media Support Services (CMSS)United States Department of Education - The Clearinghouse provides information to people with disabilities, or anyone requesting information, by doing research and providing documents in response to inquiries. Information provided includes areas of federal funding for disability-related programs. Clearinghouse staff is trained to refer requests to other sources of disability-related information, if necessary.

Clinical Updates at the American College of Gastroenterology

Information on Clinical Trials at the Mayo Clinic

Mayo Clinic is the first and largest integrated, not-for-profit group practice in the world. Doctors from every medical specialty work together to care for patients, joined by common systems and a philosophy of "the needs of the patient come first." Mayo Clinic is governed by a 33-member Board of Trustees.

Centre Hospitalier Universitaire de Nice study assessing the use of Oral Bisphosphonates in the Treatment of Osteoporosis in Non-Walking Children With Cerebral Palsy

NICHD study is to determine how fast the drug oral baclofen is cleared from the body, the correct dose, and long-term safety and efficacy for children with spasticity.

Shriners Hospitals for Children study proposes to determine if injections of BTX-A to the hamstring muscles result in measurable physiologic changes not observed with normal saline injections in children with spastic diplegic cerebral palsy who walk with a flexed-knee gait pattern.

UK clinical trial assessing the effectiveness of Treatment of Contractures with Mechanically Applied Stretch and Heat

HDI is part of a nationwide network of University Centers for Excellence. Provides a strong foundation for more than 40 research, training and service projects, addressing a wide range of topics and issues in areas such as early childhood, education and alternate assessment, transition across the lifespan, employment, community living, and personnel preparation. Funded through the Developmental Disabilities Assistance and Bill of Rights Act of 2000, and is administered through the U.S. Administration on Developmental Disabilities, U.S. Department of Health and Human Services.