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Lee Vander Loop

NEJM -- Moderate Hypothermia to Treat Perinatal Asphyxial Encephalopathy - 0 views

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    New England Journal of Medicine abstract of study to evaluate the effects of induction of moderate hypothermia in infants who had perinatal asphyxia. Study concluded that Induction of moderate hypothermia for 72 hours in infants who had perinatal asphyxia did not significantly reduce the combined rate of death or severe disability but resulted in improved neurologic outcomes in survivors. (Current Controlled Trials number, ISRCTN89547571 [controlled-trials.com] .)
Lee Vander Loop

Systemic Hypothermia Improves Outcome of Hypoxic-Ischemic Encephalopathy - 1 views

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    Completed Zhengzhou University study to investigate whether systemic hypothermia induced up to 10 hrs after birth would improve the neurodevelopmental outcome at 18 months in infants with moderate or severe HIE.
Lee Vander Loop

Late Hypothermia for Hypoxic-Ischemic Encephalopathy - 0 views

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    Clinical trial being sponsored by the Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD to evaluate whether induced whole-body hypothermia initiated between 6-24 hours of age and continued for 96 hours in infants ≥ 36 weeks gestational age with hypoxic-ischemic encephalopathy will reduce the incidence of death or disability at 18-24 months of age.
Lee Vander Loop

Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal ... - 0 views

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    Imperial College London sponsored trial in newborn infants with perinatal asphyxial encephalopathy assessing whether a combination of hypothermia and inhaled xenon preserve cerebral metabolism and structure.
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