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Duke University Clinical trial and study to evaluate the safety, tolerability, and pharmacokinetics of the study drug Pregabalin in pediatric patients with partial onset seizures in addition to measuring how much pregabalin is in your child's blood and urine after he/she takes the study drug

NINDS sponsored study will evaluate patients with muscle stiffness for possible participation in current or future research studies. It will determine the cause of muscle stiffness or cramps and measure the severity of symptoms

Neurosurgery Research & Education Foundation (NREF)

Effect of treatment on the movement disorder will be measured by a myoclonus scale and a dystonia scale as well as by assessment of overall functional status. Response at various dosages will be compared to baseline for all patients.Safety parameters including neurological examination, blood tests and EKG will be monitored throughout the treatment period and during withdrawal of the medication.

NINDS definition of dystonia

Deep Brain Stimulation: Beyond Movement Disorders By Brenda Patoine. 2010 Progress Report on Brain Research

Acute birth asphyxia is a cause of death and neurological injury. At present, there is no proven treatment; however, studies in animals suggest that brain cooling may protect against brain injury. This large multicenter trial will randomize term infants with a history of problems at delivery and signs of depression to total body cooling or standard care.

New England Journal of Medicine abstract of study to evaluate the effects of induction of moderate hypothermia in infants who had perinatal asphyxia. Study concluded that Induction of moderate hypothermia for 72 hours in infants who had perinatal asphyxia did not significantly reduce the combined rate of death or severe disability but resulted in improved neurologic outcomes in survivors. (Current Controlled Trials number, ISRCTN89547571 [controlled-trials.com] .)

National Institute of Neurological Disorders and Stroke NINDS study will use high-resolution magnetic resonance imaging (MRI) to look for subtle differences in brain anatomy between patients with focal hand dystonia (also called writer's cramp) and healthy normal volunteers. Patients with hand dystonia have prolonged muscle contractions that cause sustained twisting movements and abnormal postures. These abnormal movements often occur with activities such as writing, typing, playing certain musical instruments such as guitar or piano, or playing golf or darts.

NINDS Information Sheet on Seizures and Epilepsy: Hope through Research

NINDS Febrile Seizures Fact Sheet

The Journal of Head Trauma Rehabilitation

Definition and Anatomy of the Cerebellum from Neuroanatomy Lab Resources - Temple University

Hypotonia Information at NINDS - Includes description - treatment options - prognosis - research - clinical trials and organizations

NINDS Hydrocephalus Information Page - Definition, treatment, prognosis, research, clinical trials, organizations and additional resources rom MEDLINE Plus

In the new study, researchers led by Maiken Nedergaard, M.D., D.MSc., of the University of Rochester , showed that glutamate produced by astrocytes can trigger seizures.

NINDS - what's Old is New Again - Antibiotic Protects Nerves By Removing Excess Glutamate

NINDS - Researchers Identify a Signal for Cell Death during Stroke - In a new study, researchers have identified a signal that promotes the death of vulnerable brain cells in an animal model of stroke. In the future, drugs designed to inhibit this death signal might help reduce brain damage in stroke patients

Spasticity at University of Maryland Medical Center - Departments of Neurology and Neurosurgery - What is spasticity - Treatments - Intrathecal Baclofen Pump Therapy

Cranial CT scan on MedlinePlus - Definition - Description