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MD Movement Disorder Virtual Library - Healthcare professional's source for movement disorder news, resources and educational activities. Not-for-profit organization that has been educating and informing the movement disorder community for over a decade. WE MOVE believes that increased knowledge and understanding promote timely, accurate diagnosis and up-to-date treatment, resulting in a better quality of life for individuals affected by movement disorders.

Study will examine the effectiveness of botulinum toxin as treatment for a variety of movement disorders. The goals of the study are to refine the technique of treatment to provide the best results, to improve the understanding of how botulinum toxin works on movement disorders, and find other conditions that may be treatable with botulinum toxin.In addition, researchers also plan to study the possible use of botulinum toxin F alone and in combination with botulinum toxin A in patients who do not respond to botulinum A toxin treatment.

E-MOVE, the research news service of WE MOVE, surveys current literature and delivers brief, timely synopses of developments in movement disorders. In addition, E-MOVE covers breaking news from major medical meetings, providing important updates on the causes and treatments of movement disorders.

Study will collect information on the different ways people control limb and body movements. This information will be used to develop a database on normal movements and adaptive movements of people who have diseases that affect the way they move. The database will serve as a tool to improve diagnosis and treatment of patients with movement-related problems.

Dystonia at Movement Disorder Virtual University Resource Library - Classifications of Dystonia - Causes- Treatment and Medications - Surgical Treatments - References

Effect of treatment on the movement disorder will be measured by a myoclonus scale and a dystonia scale as well as by assessment of overall functional status. Response at various dosages will be compared to baseline for all patients.Safety parameters including neurological examination, blood tests and EKG will be monitored throughout the treatment period and during withdrawal of the medication.

Hypotonia Information at NINDS - Includes description - treatment options - prognosis - research - clinical trials and organizations

Myoclonus Information Page at National Institute of Neurological Disorders and Stroke NINDS

Clinical trial being conducted by Eunice Kennedy Shriver NationalInstitute of Child Health and Human Development NICHD to examine botulinum toxin (BOTOX, or BTX) for the treatment of muscle twitches and spasticity associated with cerebral palsy in children. Botulinum toxin is a naturally occurring bacterial toxin (botulinum toxin) that inactivates certain parts of muscles.

Running in parallel with clinical care in the Phelps Center for Cerebral Palsy and Neurodevelopmental Medicine are several Phelps Center research projects designed to improve classification and treatment for children with cerebral palsy. Using advanced neuroimaging techniques in the Kennedy Krieger Institute Kirby Research Center for Functional Brain Imaging researchers have identified specific white matter pathways that carry messages from one part of the brain to another.

University of California study compare two types of treatment of hydrocephalus: placement of a ventriculoperitoneal (VP) shunt versus an endoscopic third ventriculostomy (ETV). A second goal of this study will be to understand how the two different types of procedures, VP shunt versus ETV, affect brain blood flow and pressures.

The Neuromuscular Biomechanics Lab at Stanford University combines experimental and computational approaches to study movement. We investigate the form and function of biomechanical systems ranging from molecular motors to persons with movement disorders. We seek fundamental understanding of the mechanisms involved in the production of movement, and are motivated by opportunities to improve treatments for individuals with cerebral palsy, stroke, osteoarthritis, and Parkinson's disease.

Journal of the American Medical Assocation JAMA Abstract regarding Intrathecal Baclofen for Spasticity in Cerebral Palsy

FES is a form of treatment with a device to aid movement in people who have had damage to their brain or spinal cord. Small electrical impulses are used to excite and stimulate the nerves that supply paralyzed muscles. This research will look at any additional benefit that may occur when Botox injections are combined with specific occupational therapy exercises and with a device that uses functional electrical stimulation (FES) to help improve muscle function

Stanford University sponsored study of trihexyphenidyl in children with upper extremity dystonia due to cerebral palsy. It is hypothesized that trihexyphenidyl in doses up to 0.75mg/kg/day would be well-tolerated and show significant changes on the Melbourne scale of upper extremity function.

PubMed Abstract of study to evaluate the effect of Selective Dorsal Rhizotomy (SRD) Surgery on functional abilities in a well-defined group of ambulatory children with Spastic Diplegia

Reseach Mission is to advance neuromuscular functional assessment using objective measurements of muscle tone, strength, and gait. Goal: To apply innovative techniques to facilitate improved treatment strategies and research evaluation.Our work includes measurement of neuromuscular and musculoskeletal function and dysfunction, with emphasis on quantification of the interrelationships of muscle tone, strength, and gait related to medical diagnosis such as: *Cerebral Palsy*Parkinson's Disease*Spinal Cord Injury *Primary Progressive Multiple Sclerosis*Normal Pressure Hydrocephalus*Obesity*Normal aging *Stroke*Transverse Myelitis*Traumatic Brain Injury