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Lee Vander Loop

Study to evaluate an investigational, oral medication for epilepsy patients with uncont... - 0 views

clinicaltrials.mayo.edu/clinicaltrialdetails.cfm

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shared by Lee Vander Loop on 07 May 10 - Cached
  • Lee Vander Loop on 07 May 10
     
    Mayo study to evaluate a potential new treatment for epilepsy. Researchers want to learn if the investigational drug called perampanel is safe and can help people with partial seizures who are already taking seizure medications and the current seizure medications are not enough to control those seizures. Perampanel is being tested as a possible add-on drug for people with seizures who are taking other seizure medications.
Lee Vander Loop

Brain Infusion of Muscimol to Treat Epilepsy - 0 views

www.clinicaltrials.gov/...nct00005925

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shared by Lee Vander Loop on 10 May 10 - Cached
  • Lee Vander Loop on 10 May 10
     
    NINDS sponsored study will examine the safety and effectiveness of infusing a chemical called muscimol into the brain to control seizures in patients with intractable epilepsy (frequent seizures that persist despite therapy). Muscimol, which is similar to a naturally occurring brain chemical called GABA, has been shown to reduce seizures in rats.
Lee Vander Loop

A Study on the Effectiveness and Safety of Diazepam Injection (Vanquix™) for ... - 0 views

www.clinicaltrials.gov/...NCT00319501

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shared by Lee Vander Loop on 14 May 10 - Cached
  • Lee Vander Loop on 14 May 10
     
    Safety and Efficacy of Vanquix™ Auto-Injector (Diazepam Injection) for the Management of Selected, Refractory Patients With Epilepsy Who Require Intermittent Medical Intervention to Control Episodes of Acute Repetitive Seizures
Lee Vander Loop

Pregabalin in Pediatric Patients with Partial Onset Seizures - DukeHealth.org - 0 views

www.dukehealth.org/...ts_with_partial_onset_seizures

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shared by Lee Vander Loop on 07 May 10 - Cached
  • Lee Vander Loop on 07 May 10
     
    Duke University Clinical trial and study to evaluate the safety, tolerability, and pharmacokinetics of the study drug Pregabalin in pediatric patients with partial onset seizures in addition to measuring how much pregabalin is in your child's blood and urine after he/she takes the study drug
Lee Vander Loop

Drug Trial for Children with Partial Onset Seizures - DukeHealth.org - 0 views

www.dukehealth.org/...en_with_partial_onset_seizures

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shared by Lee Vander Loop on 07 May 10 - Cached
  • Lee Vander Loop on 07 May 10
     
    Duke University and Multicenter, Open-label Study to Investigate the Safety, Tolerability and Pharmacokinetics of Lacosamine (LCM) Oral Solution (syrup) as Adjunctive Therapy in Children with Partial Onset Seizures. This study is being done to test the safety of the study drug Lacosamide (LCM) syrup and how the body processes it.
Lee Vander Loop

Pilot Study of Bumetanide for Newborn Seizures - 0 views

clinicaltrials.gov/...NCT00830531

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shared by Lee Vander Loop on 10 May 10 - Cached
  • Lee Vander Loop on 10 May 10
     
    Study to obtain pharmacokinetic and safety data of bumetanide in newborns with refractory seizures. The overall hypothesis is that bumetanide, added to conventional antiepileptic (antiseizure) medications, will be a safe and well tolerated medication, compared with conventional antiepileptic drugs alone.
Lee Vander Loop

Mayo Clinical Trial - Prospective Seizure Frequency Clinical Investigation - 0 views

clinicaltrials.mayo.edu/clinicaltrialdetails.cfm

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shared by Lee Vander Loop on 07 May 10 - Cached
  • Lee Vander Loop on 07 May 10
     
    Mayo research study to determine if there are enough patients with hard to treat epilepsy that might qualify for a future study of a medical device that is being developed to treat epilepsy. Participants will not be testing the device during this study. The study doctor will be assessing seizure type(s) and determine how frequently they occur, and to verify if antiseizure medications can be held constant for a period of 12 weeks.
Lee Vander Loop

Automated Response to Spontaneous Epileptiform Activity Using the External Responsive N... - 0 views

clinicaltrials.mayo.edu/clinicaltrialdetails.cfm

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shared by Lee Vander Loop on 07 May 10 - Cached
  • Lee Vander Loop on 07 May 10
     
    Study being conducted to learn about the effects (both good and bad) of a brain stimulating device known as the External Responsive Neurostimulating System. This is an investigational device that was designed to detect seizure activity and give an electrical stimulation to the brain to try to stop it
Lee Vander Loop

The Role of Serotonin in Seizures - 0 views

www.clinicaltrials.gov/...nct00439387

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shared by Lee Vander Loop on 10 May 10 - Cached
  • Lee Vander Loop on 10 May 10
     
    NINDS sponsored study will investigate the role that a brain chemical called serotonin plays in seizures. Serotonin, present naturally in the brain, helps transmit signals between nerve cells. Glucose is a sugar that is the main fuel of the brain.
Lee Vander Loop

Study the Efficacy and Safety of Diazepam Auto-injector for Controled Episodes of Acute... - 0 views

www.clinicaltrials.gov/...NCT01079156

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shared by Lee Vander Loop on 14 May 10 - Cached
  • Lee Vander Loop on 14 May 10
     
    Study sponsored by the university of Chicago to demonstrate the efficacy and safety of Vanquix for the management of acute repetitive seizures (ARS). Study will provide clinical evidence for the effective and safe use of a diazepam auto-injector, Vanquix, to provide patients and their caregivers with an alternative to rectal administration.
Lee Vander Loop

Efficacy, Safety and Tolerability of TRI476 (Oxcarbazepine) in Children With Inadequate... - 0 views

clinicaltrials.gov/...NCT00975715

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shared by Lee Vander Loop on 21 Jun 10 - Cached
  • Lee Vander Loop on 21 Jun 10
     
    Study is designed to provide short term efficacy and safety data of TRI476 in children with inadequately-controlled partial seizures. The purpose of study is to confirm that TRI476 as adjunctive therapy is effective and safe.
Lee Vander Loop

NINDS - Better Understanding of Newborn Seizures Leads to Potential New Treatment - 1 views

www.ninds.nih.gov/...nical_uncoupling_explained.htm

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shared by Lee Vander Loop on 28 Apr 10 - Cached
  • Lee Vander Loop on 28 Apr 10
     
    Information and news on study funded by National Institute of Neurological Disorders and Stroke (NINDS) helps explain why newborn brain responds differently to anticonvulsant medications.
Lee Vander Loop

Responsive Neurostimulator System Feasibility Clinical Investigation - 0 views

clinicaltrials.mayo.edu/clinicaltrialdetails.cfm

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shared by Lee Vander Loop on 07 May 10 - Cached
  • Lee Vander Loop on 07 May 10
     
    Mayo Clinic researchers are looking at a new procedure that involves surgically placing a Responsive Neurostimulator (RNS) in the brain that may be able to suppress seizures in patients with epilepsy
Lee Vander Loop

Electroencephalography (EEG) and Deep Brain Stimulation (DBS) in Epilepsy" - Weill Medi... - 0 views

www.clinicaltrials.gov/...NCT00194870

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shared by Lee Vander Loop on 28 May 10 - Cached
  • Lee Vander Loop on 28 May 10
     
    Patients with epilepsy undergoing deep brain stimulation (DBS) have electroencephalograms (EEGs) recorded before and during their stimulation treatment. Subsequently we will be using computer-assisted analysis of the digitally-recorded EEG signals to assess the effects of DBS on the brain-wave frequency content and any abnormal seizure-like patterns that may be present.
Lee Vander Loop

Ketogenic Diet for Child Epilepsy and Seizure Control - 0 views

clinicaltrials.gov/...NCT00004729

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shared by Lee Vander Loop on 30 Apr 10 - Cached
  • Lee Vander Loop on 30 Apr 10
     
    Information on completed study to assess if the classic ketogenic diet is effective in reducing seizure frequency, and medication toxicity
Lee Vander Loop

Research Study for Brothers and Sisters with Epilepsy, Cincinnati Children's Hospital M... - 0 views

www.cincinnatichildrens.org/...epilepsy-siblings.htm

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shared by Lee Vander Loop on 07 May 10 - No Cached
  • Lee Vander Loop on 07 May 10
     
    Cincinnati Children's is conducting a research study, sometimes known as a clinical trial or clinical study, to better understand what causes epilepsy and the role our genes play, which treatments will be more effective, and why some families have multiple relatives with seizures
Lee Vander Loop

Language Mapping in Patients With Epilepsy - 0 views

www.clinicaltrials.gov/...nct00706160

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shared by Lee Vander Loop on 10 May 10 - Cached
  • Lee Vander Loop on 10 May 10
     
    NINDS sponsored study will examine how certain language skills, such as naming objects, understanding spoken language and reading are organized in the brain and how they are affected by seizures.
Lee Vander Loop

Lamotrigine Cognitive Function Study in Adult Untreated Epilepsies - Full Text View - C... - 0 views

clinicaltrials.gov/...NCT00896987

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shared by Lee Vander Loop on 21 Jun 10 - Cached
  • Lee Vander Loop on 21 Jun 10
     
    Korean study comparing the effect of anti-epileptic drugs' (AEDs) long-term treatment on cognitive function. This study is an open-label, randomized, multicenter comparative trial of lamotrigine versus carbamazepine"
Lee Vander Loop

Epilepsy Drug Discovery - Carnegie Mellon University - 0 views

www.cmu.edu/...epilepsy-drug-discovery.shtml

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shared by Lee Vander Loop on 27 May 10 - Cached
  • Lee Vander Loop on 27 May 10
     
    Preventing Seizure Progression - Carnegie Mellow University researchers have identified a new anticonvulsant compount that has the potential to stop the development of epilepsy. Findings are published in the journal Epilepsia.
Lee Vander Loop

Study to Evaluate the Safety and Effectiveness of USL255 in Patients With Refractory Pa... - 0 views

clinicaltrials.gov/...NCT01142193

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shared by Lee Vander Loop on 21 Jun 10 - Cached
  • Lee Vander Loop on 21 Jun 10
     
    A Randomized, Multicenter, Double-blind, Placebo-controlled, Parallel-group Phase 3 Study to Evaluate the Efficacy and Safety of USL255 as Adjunctive Therapy in Patients With Refractory Partial-Onset Seizures
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