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Johns Hopkins study - Study concluded that daily Potasssium Citrate wards off Kidney Stones in Seizure patients on High Fat Diet

Mayo study to look for genes that are the cause of epilepsy and to look for genes that have an impact on the effectiveness of over the counter and prescription medicines used to treat epilepsy.

Completed study that evaluated the efficacy of surgical resection of an identifiable zone of cortical abnormality versus multiple drug therapy in children with infantile spasms refractory to standard therapy: II. Assess how infantile spasms interfere with development and whether this is partially reversible. III. Determine the predictors of good surgical outcome and whether surgery permanently controls seizures and improves development.

Intraoperative Optical Imaging Mapping of Neocortical Epilepsy in Human

In the new study, researchers led by Maiken Nedergaard, M.D., D.MSc., of the University of Rochester , showed that glutamate produced by astrocytes can trigger seizures.

This study is part of a series of studies that will explore how the mind and the brain work to cause episodes of uncontrollable shaking in people who have no known underlying brain or medical disorder. The study is conducted at NIH and at the Brown University Rhode Island Hospital.

Study comparing diazepam, a drug that is labeled by the FDA for this indication, with lorazepam. The study will show whether one drug is more effective and safer than the other.

The investigators study aims to investigate the pharmacokinetic and pharmacodynamic differences of dexmedetomidine between patients receiving and not receiving enzyme-inducing anticonvulsant therapy and to identify a potential mechanism for these differences.

Government sponsored effort designed to provide early incentives that encourage and facilitate the discovery of new therapeutic agency.

Pilot study to evaluate the efficacy and tolerability of the modified Atkins diet in infantile spasms refractory to conventional treatment (ACTH, vigabatrin, and anti-epileptic drugs).

Multicenter, randomized, controlled trial to compare the anti-seizure effect of parenteral MgSO4 versus oral labetalol in hypertensive pregnant women who are eligible for MgSO4 therapy. The primary outcome measure is eclampsia, and the secondary outcome measures include blood pressure control, and relevant antenatal, intrapartum, and postnatal maternal and fetal/neonatal parameters including adverse effects and complications.

Research/study hypothesis is that topiramate will reduce acute seizures after traumatic brain injury and will help prevent the development of epilepsy after traumatic brain injury.

Study to compare Short-term ketogenic diet with conventional long-term trial in refractory infantile spasms.

Study to determine if a therapy regiment of the medication Hemin can improve symptoms in diabetic patients with gastroparesis (slow gastric emptying). We want to test the effects of this new medication on the rate at which food empties from your stomach and on your symptoms