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NINDS sponsored study will investigate the role that a brain chemical called serotonin plays in seizures. Serotonin, present naturally in the brain, helps transmit signals between nerve cells. Glucose is a sugar that is the main fuel of the brain.

NINDS sponsored study will examine the safety and effectiveness of infusing a chemical called muscimol into the brain to control seizures in patients with intractable epilepsy (frequent seizures that persist despite therapy). Muscimol, which is similar to a naturally occurring brain chemical called GABA, has been shown to reduce seizures in rats.

Citicoline Brain Injury Treatment (COBRIT) trial of the effects of 90 days of citicoline on functional outcome in patients with complicated mild, moderate and severe traumatic brain injury. Citicoline (also known as CDP-Choline) is a naturally occurring endogenous compound. Citicoline may have neuroprotective effects and may potentiate neuro-recovery which has led to the evaluation of it as treatment for both stroke and TBI in animal models and in human clinical trials.

Oxfordjouornals.org - Brain - A review of differences between basal ganglia and cerebellar control of movements as revealed by functional imaging studies.

NINDS sponsored study will examine how the areas in the brain are connected when they are controlling two finger movements at the same time. Study will examine how people use what they see to help guide two different movements. Studying will further examine the connectivity between the homologous motor areas of the two hemispheres, and between prefrontal cortex and parietal cortex, to understand sensorimotor integration processes during competitive and cooperative dual tasks.

Anatomy of the Brain - Cerebral Cortex at biology.about.com - Includes Function, Location and Images

F.M. Kirby Research Center for Functional Brain Imaging at the Kennedy Krieger Institute. The Kirby Center supports both a central technology support staff and affiliated research scientists. Together they provide training and research advice for all aspects of the Center's imaging technologies. Research resource where imaging scientists, neuroscientists, and clinicians collaborate to study brain function.

Long-term evaluation of granulocyte-colony stimulating factor on hypoxic-ischemic brain damage in infant rats. Hypoxia-ischemia (HI), as a major cause of fetal brain damage, has long-lasting neurological implications. Therefore, therapeutic interventions that attenuate the neuropathological out come of HI while also improving the neurofunctional outcome are of paramount clinical importance. The aim of this study was to investigate the long-term functional and protective actions of granulocyte-colony stimulating factor (G-CSF) treatment in an experimental model of cerebral. RESULTS: Granulocyte-colony stimulation promoted somatic growth and prevented brain atrophy and underdevelopment of the heart in infant rats.

The Johns Hopkins Medicine Brain Science Institute's (BSi) mission is to solve fundamental questions about brain development and function and to use these insights to understand the mechanisms of brain disease

PubMed Abstract of French article describing the relationship between the brain and digestive function.

Running in parallel with clinical care in the Phelps Center for Cerebral Palsy and Neurodevelopmental Medicine are several Phelps Center research projects designed to improve classification and treatment for children with cerebral palsy. Using advanced neuroimaging techniques in the Kennedy Krieger Institute Kirby Research Center for Functional Brain Imaging researchers have identified specific white matter pathways that carry messages from one part of the brain to another.

NINDS sponsored study will examine how certain language skills, such as naming objects, understanding spoken language and reading are organized in the brain and how they are affected by seizures.

Neuroscience for Kids - Anatomy of the Brain - Functional Divisions of the Cerebral Cortex

Completed study sponsored by NINDS designed to use positron emission tomography to measure brain energy use. Positron Emission Tomography (PET) is a technique used to investigate the functional activity of the brain. The PET technique allows doctors to study the normal processes of the brain (central nervous system) of normal individuals and patients with neurologic illnesses without physical / structural damage to the brain.

Study to determine if hormone replacement in TBI patients with documented abnormalities in the GH, thyroid, or cortisol axis will improve muscle function, body composition, aerobic capacity (GH) and tests of neuropsychologic function (GH, thyroid, cortisol).

Study will examine how the brain controls speech in patients with spasmodic dysphonia, a voice disorder that involves involuntary spasms of muscles in the larynx (voice box), causing breaks in speech. Although the causes of spasmodic dysphonia are unknown, recent studies found changes in brain function in patients with the disorder that may play a role in its development.

CNS Centre for Neuro Skills TBI Resource Guide - Cerebellum - Brain Map

CCSI consortium on Cognitive Science Instruction - Neurons, Synapses, action Potentials, and Neurotransmission - Function of neurons - The central nervous system CNS, Neuron basic information, function and description

FES is a form of treatment with a device to aid movement in people who have had damage to their brain or spinal cord. Small electrical impulses are used to excite and stimulate the nerves that supply paralyzed muscles. This research will look at any additional benefit that may occur when Botox injections are combined with specific occupational therapy exercises and with a device that uses functional electrical stimulation (FES) to help improve muscle function

PEDIATRICS - Official Journal of the American Academy of Pediatris - Vol. 113, No. 2, 2004. Study assessing Constraint-Induced Movement therapy. Constraint-Induced Movement (CI) therapy has been found to be a promising treatment for substantially increasing the use of extremities affected by such neurologic injuries as stroke and traumatic brain injury in adults. The purpose of this study was to determine the applicability of this intervention to young children with cerebral palsy. Study concluded that Pediatric Constraint Induced Therapy produced major and sustained improvement in motoric function in the young children with hemiparesis in the study.