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Observational cohort study designed to identify the mechanisms of disease in patients with preterm labor/contractions and preterm premature rupture of membranes and to describe the relationship between clinical, biochemical, histological, biophysical parameters and the development of infant neurological disorders.

NIH PUbMed Abstract of Russian study documenting the Physical and neurological state of the newborn afer perinatal asphyxia.This paper is presented as modern conceptions about asphyxia origin, risk factors, neurological and systemic complications for child nervous system and organism.

PEDIATRICS - Official Journal of the American Academy of Pediatris - Vol. 113, No. 2, 2004. Study assessing Constraint-Induced Movement therapy. Constraint-Induced Movement (CI) therapy has been found to be a promising treatment for substantially increasing the use of extremities affected by such neurologic injuries as stroke and traumatic brain injury in adults. The purpose of this study was to determine the applicability of this intervention to young children with cerebral palsy. Study concluded that Pediatric Constraint Induced Therapy produced major and sustained improvement in motoric function in the young children with hemiparesis in the study.

Duke University and Multicenter, Open-label Study to Investigate the Safety, Tolerability and Pharmacokinetics of Lacosamine (LCM) Oral Solution (syrup) as Adjunctive Therapy in Children with Partial Onset Seizures. This study is being done to test the safety of the study drug Lacosamide (LCM) syrup and how the body processes it.

Mayo research study to determine if there are enough patients with hard to treat epilepsy that might qualify for a future study of a medical device that is being developed to treat epilepsy. Participants will not be testing the device during this study. The study doctor will be assessing seizure type(s) and determine how frequently they occur, and to verify if antiseizure medications can be held constant for a period of 12 weeks.

Journal of Pediatric Neurosciences - provides articles and abstract article of studies and research in the field of pediatric neurology

Completed study. Objective of this project was to develop and evaluate two different alternative or complementary medical modalities that have been used in children with cerebral palsy by practitioners in an attempt to decelerate the complications from the neurologic insult and resultant muscle imbalance.

Duke University Clinical trial and study to evaluate the safety, tolerability, and pharmacokinetics of the study drug Pregabalin in pediatric patients with partial onset seizures in addition to measuring how much pregabalin is in your child's blood and urine after he/she takes the study drug

Information on completed clinical trial conducted to assess the safety and efficacy of oral Glycopyrrolate Liquid in the management of problem drooling associated with cerebral palsy or other neurologic conditions in children

European study to find out whether 4 different protein sources affect the rate of gastric emptying and electrofysiology in this group of children.The protein composition of nutrition may affect the rate of gastric emptying and gastric fysiology. This is especially important in children with neurologic impariment, who commonly rely on tube feedings, have feeding problems, nausea, vomiting, gastroesophageal reflux and delayed gastric emptying.

Information on Study sponsored by the National Institute of Neurological Disorders and Stroke. Study completed and examined how the brain controls movements in patients with certain types of cerebral palsy. Last updated March 2008

Effect of treatment on the movement disorder will be measured by a myoclonus scale and a dystonia scale as well as by assessment of overall functional status. Response at various dosages will be compared to baseline for all patients.Safety parameters including neurological examination, blood tests and EKG will be monitored throughout the treatment period and during withdrawal of the medication.

Journal of Child Neurology - Study Abstract: Significance of Microcephaly Among Children with Developmental Disabilities

NINDS Release - Study Finds Psychiatric Disorders are Common in People with Cerebellar Degeneration

PubMed Study Abstract: Ten indicators available during the first two hours of life, such as clinical criteria of neonatal distress and postnatal arterial blood gases, were compared with the neonatal neurological course in sixty full term newborns with significant birth asphyxia in order to test their value for the diagnosis and the short-term prognosis of severe birth asphyxia. Birth asphyxia was defined as severe when it was followed by symptoms of moderate or severe post-asphyxial encephalopathy.

Information and news on study funded by National Institute of Neurological Disorders and Stroke (NINDS) helps explain why newborn brain responds differently to anticonvulsant medications.

NINDS sponsored study will evaluate patients with muscle stiffness for possible participation in current or future research studies. It will determine the cause of muscle stiffness or cramps and measure the severity of symptoms

NINDS sponsored and multi-center collaborative study will establish a database of information about stroke in infants and children

National Library of Medicine - National Institute of Health - PubMed Article Abstract: Floppy infant syndrome - Review - On long-term follow up, cerebral palsy and mental retardation turn out to be the 2 most common causes of FIS. This review focuses on neuromuscular causes of FIS. With the advent of molecular diagnosis, a few conditions can be diagnosed by DNA analysis of the peripheral lymphocytes (myotonic dystrophy, spinal muscular atrophy); however, for the most part, electrodiagnostic studies and muscle biopsy remain as essential diagnostic tools for FIS.

Information regarding ongoing study to evaluate the use of dexmedetomidine for sedation during EEGs in patients with neurological disorders.