WSU BIOL209 Microbiology

Interesting study on the possibility of using the Newcastle disease virus to treat prostate cancer. They modified the virus so that it replicates only in the presence of an active prostate-specific antigen. There are only mild side effects in humans although this is a fatal disease in domestic birds (I remember one of the former companies I worked for working on this vaccine for birds).

A new study analyses the impact of animal brucellosis and bovine tuberculosis (BTB) on animals and people in urban, peri-urban and rural Niger. The World Health Organization (WHO) ranks them as major zoonoses, infectious diseases transmitted between species.

Worried about mutating to be able to pass from person to person

Scientists have discovered that the removal of the protein calpain can prevent the spread of infectious bacteria that have acquired immunity to antibiotics. Bacteria such as Listeria use the protein for growth and movement to different cellular compartments. The removal of calpain prevents bacterial movement which in turn inhibits growth.

Supplementary paper for presentation.

Supplemental paper for presentation.

Genetic sequencing of the current H7N9 outbreak in China has revealed the ability of the virus to adapt to a human host

Supplemental paper for presentation.

Supplemental paper for presentation.

Mediators of Inflammation is a peer-reviewed, open access journal that publishes original research and review articles on all types of inflammatory mediators, including cytokines, histamine, bradykinin, prostaglandins, leukotrienes, PAF, biological response modifiers and the family of cell adhesion-promoting molecules.

Bernhard Kaltenboeck, Editor Abstract Debilitating infectious diseases caused by Chlamydia are major contributors to the decline of Australia's iconic native marsupial species, the koala ( Phascolarctos cinereus). An understanding of koala chlamydial disease pathogenesis and the development of effective strategies to control infections continue to be hindered by an almost complete lack of species-specific immunological reagents.

Frontiers | Who possesses drug resistance genes in the aquatic environment?: sulfamethoxazole (SMX) resistance genes among the bacterial community in water environment of Metro-Manila, Philippines | Frontiers in Antimicrobials, Resistance and Chemotherapy publishes articles on the most outstanding discoveries across the research spectrum of Frontiers | Who possesses drug resistance genes in the aquatic environment?: sulfamethoxazole (SMX) resistance genes among the bacterial community in water environment of Metro-Manila, Philippines | Antimicrobials, Resistance and Chemotherapy.

The prevalence and type of plasmids, resistance genes and integrons carried by two collections of multiresistant E. coli producing or not extended-spectrum β-lactamases have been compared. Rep-PCR was used to determine the clonal relationship of the organisms. Plasmids were classified according to their incompatibility.

Bacterial cultivation requires consideration of three things: The bacterial strain, cultivation medium, and cultivation conditions. Most microbiologists dutifully report their choice of strains and cultivation media in manuscripts; however, these same microbiologists often overlook reporting cultivation conditions. Without this information, it is difficult to determine if cultures were grown aerobically, microaerobically, or anaerobically.

A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project Consortium has established a population-scale framework to develop metagenomic protocols, resulting in a broad range of quality-controlled resources and data including standardized methods for creating, processing and interpreting distinct types of high-throughput metagenomic data available to the scientific community. An ambitious article found in another article I enjoyed reading. Was incredibly interested to find out that the vaginal microbiota of pregnant women was significantly different from non-pregnant and to find that these microbiota are preparing the soon to be born baby with it's own microbiota!! (http://www.nytimes.com/2012/06/19/science/studies-of-human-microbiome-yield-new-insights.html?ref=microbiology)

Read an article on a fermentation guru (http://www.nytimes.com/2012/09/19/dining/fermentation-guru-helps-chefs-find-new-flavors.html?pagewanted=2&ref=microbiology), so was interested in finding an article on fermentation and found this article on the fermentation of wine mixing species of yeasts and the benefits. The use of a multistarter fermentation process with S. cerevisiae and non-Saccharomyces wine yeasts has been proposed to simulate natural must fermentation and to confer greater complexity and specificity to wine. The advantage of this process is to simulate a spontaneous process avoiding the risks of stuck fermentation. Furthermore, non-Saccharomyces wine strains could have some specific enological characteristics that are absent in S. cerevisiae species, leading to combined, synergic and/or additive effects on the final wine.

This is the article of my last post, I obviously understand the two last posts count as one as they are the same topic. I simply wanted supplementary information for both since you cannot see this full text and the previous post was from .net.