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Katelyn Madigan

Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders? - 1 views

  • gut microbiota differs at the phylum level depending on weight status
  • human obesity is associated with a low abundance of intestinal Bacteroidetes and high abundance of Firmicutes
  • The mere presence of gut microbiota has recently been shown to contribute to obesity
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    With the further studies in ratios of gut microbes found in people of varying weights, there are different treatments also being performed on people that undergo bypass surgery to alter the gut microbes to sustain weight loss.
Whitney Hopfauf

Eczema in infants linked to gut bacteria - 0 views

  • Eczema is a chronic inflammation of the epidermis
    • Whitney Hopfauf
       
      The flora of the gut is being implicated in so many more diseases than ever before. I remember when the probiotic craze first started and now it has become common knowledge. Maybe we could someday treat eczema by repopulating the gut with bacteroidetes (at least in children)
  • The number of bifidobacteria naturally falls with age and in total we found 21 groups of bacteria which changed in this time period.
    • Whitney Hopfauf
       
      I remember when I was growing up, my pediatrician put me on a special kind of milk that had extra probiotics in it to combat my constant ear infections. Maybe there was more validity to that than I realized.
  • early change towards adult-type bacteria which seems to be a risk factor for eczema
    • Whitney Hopfauf
       
      I wonder what would happen in the reverse (if childhood bacterial flora was present in adults). I wonder if there is a pathology associated with that.
  • ...5 more annotations...
  • gut bacteria
  • with or without eczema was examined when they were six and 18 months ol
  • normally
  • six months all the infants had the same types of bacteria but by 18 months old the children with eczema had more of a type of bacteria normally associated with adult
  • while the healthy children had a greater amount of Bacteroidetes.
anonymous

Gut bugs are implicated in heart attacks and stroke - 0 views

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    Gut bacteria turns lecithin, which is within egg yolks, liver, beef, pork and wheat into TMAO causing heart disease. Stroke and heart attack can be caused by the potent TMAO, which hardens the artery by cholesterol build up on the artery walls. A nutrient within red meat and dairy, carnitine, can be transformed to TMAO by gut bugs. However, this is usually only in frequent meat eater. People that infrequently each meat reducing the amount of gut bacteria to transform the carnitine into TMAO.
Elijah Velasquez

A new way to lose weight? Study shows that changes to gut microbiota may play role in w... - 0 views

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    New research, conducted in collaboration with researchers at Massachusetts General Hospital, has found that the gut microbes of mice undergo drastic changes following gastric bypass surgery. This is quite an astounding discovery. Finding ways to manipulate microbial populations can potentially open doors for alternatives to weight loss and fighting off bacteria.
Elijah Velasquez

Poultry probiotic cuts its coat to beat bad bacteria - 0 views

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    The probioitc L. johnsonii has the ability to alter its coat. The alteration protects the bacteria from stomach acids and helps them come together to form biofilms. This increases colonization within the gut and could prevent C. perfringens from colonising the gut. This is a very interesting approach and is comparable to the actions of natural flora within humans.
Casey Finnerty

Study Points to New Culprit in Heart Disease - NYTimes.com - 0 views

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    NYTimes report on Nathan's post about carnitine and it's conversion to TMAO by gut bacteria.
Charles Bach

Gut bacteria byproduct predicts heart attack and stroke - 0 views

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    Looking at the micro flora in the gut researchers are showing that this correlates to heart disease. Another story of the great importance of bacteria in our bodies.
Casey Finnerty

Probiotic Logic vs. Gut Feelings - NYTimes.com - 1 views

  • Still, he added, taking them doesn’t seem harmful. “It’s a relatively low-cost treatment worth trying if you have a condition like Crohn’s disease,” he said. “But for most conditions, the potential benefit is uncertain.”
  • There is growing evidence for the role of the appendix in restoring a healthful balance of microbes in the body.
  • The challenge in taking probiotics is to get the microbes past the stomach, where most are killed by gastric acid, said Robert Dunn, a biologist at North Carolina State University. Once in the intestines, they must compete effectively with the microbes already present.
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    I always wondered how the probiotics we get from yogurt etc. were supposed to make it past the stomach. If the stomach does indeed neutralize probiotics, does eating yogurt to prevent antibiotic associated diarrhea (for instance) really help?
Casey Finnerty

'We Have a Limited Window of Opportunity': CDC Warns of Resistance 'Nightmare' | Wired ... - 0 views

  • “We have a very serious problem, and we need to sound an alarm.”
  • Healthcare institutions in 42 states have now identified at least one case of CRE. The occurrence of this resistance in the overall family of bacteria has risen at least four-fold over 10 years. In the CDC’s surveillance networks, 4.6 percent of hospitals and 17.8 percent of long-term care facilities diagnosed this bug in the first half of 2012.
  • CRE stands for “carbapenem-resistant Enterobacteriaceae.” Enterobacteriaceae are a family of more than 70 bacteria which share the characteristic of being gut-dwelling (“entero”)
  • ...3 more annotations...
  • the CDC reviewed six steps that they first published last year in a CRE Toolkit and want health care facilities to take:
  • But an important point is that none of this is required, and none of this is funded.
  • There are no reimbursements, under Medicare, for infection-control as a hospital task
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    This article does a good job summarizing this week's announcement by the CDC director on the gravity of the CRE problem.
Casey Finnerty

Molecule in meat may increase heart disease risk | Genes & Cells | Science News - 3 views

  • Hazen’s group also found that blood levels of TMAO and L-carnitine could predict heart disease risk, which they learned by collecting blood samples from 2,595 patients and tracking their health for three years.
    • Casey Finnerty
       
      That is a fairly large sample size and long term study.
  • Molecules proposed as biomarkers for heart disease often look promising in initial studies but fizzle out clinically. “We’ve been down this road so many times before.”
    • Casey Finnerty
       
      Very true.
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    This is an interesting story on how the microbiota of our gut may play an indirect role in cardiovascular disease.
Casey Finnerty

Eggs, Too, May Provoke Bacteria to Raise Heart Risk - NYTimes.com - 0 views

  • The lecithin study, published Wednesday in The New England Journal of Medicine, is part of a growing appreciation of the role the body’s bacteria play in health and disease. With heart disease, investigators have long focused on the role of diet and heart disease, but expanding the scrutiny to bacteria adds a new dimension.
  • “Heart disease perhaps involves microbes in our gut,”
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    First carnitine and meat, now lecithin and eggs! Darn it! All things in moderation, I guess.
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