Mediators of Inflammation is a peer-reviewed, open access journal that publishes original research and review articles on all types of inflammatory mediators, including cytokines, histamine, bradykinin, prostaglandins, leukotrienes, PAF, biological response modifiers and the family of cell adhesion-promoting molecules.

Bernhard Kaltenboeck, Editor Abstract Debilitating infectious diseases caused by Chlamydia are major contributors to the decline of Australia's iconic native marsupial species, the koala ( Phascolarctos cinereus). An understanding of koala chlamydial disease pathogenesis and the development of effective strategies to control infections continue to be hindered by an almost complete lack of species-specific immunological reagents.

Frontiers | Who possesses drug resistance genes in the aquatic environment?: sulfamethoxazole (SMX) resistance genes among the bacterial community in water environment of Metro-Manila, Philippines | Frontiers in Antimicrobials, Resistance and Chemotherapy publishes articles on the most outstanding discoveries across the research spectrum of Frontiers | Who possesses drug resistance genes in the aquatic environment?: sulfamethoxazole (SMX) resistance genes among the bacterial community in water environment of Metro-Manila, Philippines | Antimicrobials, Resistance and Chemotherapy.

The prevalence and type of plasmids, resistance genes and integrons carried by two collections of multiresistant E. coli producing or not extended-spectrum β-lactamases have been compared. Rep-PCR was used to determine the clonal relationship of the organisms. Plasmids were classified according to their incompatibility.

Bacterial cultivation requires consideration of three things: The bacterial strain, cultivation medium, and cultivation conditions. Most microbiologists dutifully report their choice of strains and cultivation media in manuscripts; however, these same microbiologists often overlook reporting cultivation conditions. Without this information, it is difficult to determine if cultures were grown aerobically, microaerobically, or anaerobically.

A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project Consortium has established a population-scale framework to develop metagenomic protocols, resulting in a broad range of quality-controlled resources and data including standardized methods for creating, processing and interpreting distinct types of high-throughput metagenomic data available to the scientific community. An ambitious article found in another article I enjoyed reading. Was incredibly interested to find out that the vaginal microbiota of pregnant women was significantly different from non-pregnant and to find that these microbiota are preparing the soon to be born baby with it's own microbiota!! (http://www.nytimes.com/2012/06/19/science/studies-of-human-microbiome-yield-new-insights.html?ref=microbiology)

Read an article on a fermentation guru (http://www.nytimes.com/2012/09/19/dining/fermentation-guru-helps-chefs-find-new-flavors.html?pagewanted=2&ref=microbiology), so was interested in finding an article on fermentation and found this article on the fermentation of wine mixing species of yeasts and the benefits. The use of a multistarter fermentation process with S. cerevisiae and non-Saccharomyces wine yeasts has been proposed to simulate natural must fermentation and to confer greater complexity and specificity to wine. The advantage of this process is to simulate a spontaneous process avoiding the risks of stuck fermentation. Furthermore, non-Saccharomyces wine strains could have some specific enological characteristics that are absent in S. cerevisiae species, leading to combined, synergic and/or additive effects on the final wine.

This is the article of my last post, I obviously understand the two last posts count as one as they are the same topic. I simply wanted supplementary information for both since you cannot see this full text and the previous post was from .net.

Scientists are reporting "laboratory resurrections" of several 2-3-billion-year-old proteins that are ancient ancestors of the enzymes that enable today's antibiotic-resistant bacteria to shrug off huge doses of penicillins, cephalosporins and other modern drugs.

Abstract While Chlamydia trachomatis infections are frequently asymptomatic, mechanisms that regulate host response to this intracellular Gram-negative bacterium remain undefined. This investigation thus used peripheral blood mononuclear cells and endometrial tissue from women with or without Chlamydia genital tract infection to better define this response.... The focus paper of me and Samantha Mishall's presentation on Tuesday April 30th.

Researchers have identified a biomarker, an eight gene "signature" (a group of genes in a cell whose combined expression is uniquely characteristic of a medical condition), that predicts how long cancer patients might survive without relapse after undergoing chemotherapy. They found that this eight gene signature show a strong correlation to an elevated response to five chemotherapy agents, and showed a lower risk of recurrence and longer relapse-free survival.

Curious if this eight gene signature is a result of the genetics of our cell (and resultant interactions) or if it entirely up to the cancerous agent? In simpler terms, are we genetically prone to this eight gene signature or is it luck that our cancer results in this eight gene signature?