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Megan Goldman

Starmerella bombicola influences the metabolism of Saccharomyces cerevisiae at pyruvate... - 0 views

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    Read an article on a fermentation guru (http://www.nytimes.com/2012/09/19/dining/fermentation-guru-helps-chefs-find-new-flavors.html?pagewanted=2&ref=microbiology), so was interested in finding an article on fermentation and found this article on the fermentation of wine mixing species of yeasts and the benefits. The use of a multistarter fermentation process with S. cerevisiae and non-Saccharomyces wine yeasts has been proposed to simulate natural must fermentation and to confer greater complexity and specificity to wine. The advantage of this process is to simulate a spontaneous process avoiding the risks of stuck fermentation. Furthermore, non-Saccharomyces wine strains could have some specific enological characteristics that are absent in S. cerevisiae species, leading to combined, synergic and/or additive effects on the final wine.
Katelyn Madigan

Rory Staunton: Boy, 12, dies after 'doctors fail to spot infection ravaging his body' |... - 0 views

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    This is the shocking article that was talked about during class. This just shows how we all have to take these warning signs seriously and realize there are risks with exposure in every day incidents.
Amy Jorgenson

Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations a... - 0 views

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    This paper does an excellent job researching the correlation of the methylation of the STAT-1 gene and genetic mutations in coccidiodiomycosis and histoplasmosis. The paper shows evidence of the methylation of the STAT-1 by the PIAS1 protein. This gene mutation immunologically challenges the IFN-γ and alters the body's defense mechanisms. Excellent paper on a very scary disease. Hopeful for a vaccine!!! 
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    This article was used as a resource for our presentation. This is the article where we obtained the information regarding the patient case studies.
Casey Finnerty

The Virus That Learns - Phenomena: The Loom - 0 views

  • Likewise, restriction enzymes are a dangerous defense, because they can chop up the distinctive stretches of DNA in a bacterium’s own genes. It avoids attacking itself by capping those sequences in its own DNA, so that the restriction enzymes can’t reach them.
  • Some species can muck up the production of new viruses, stealing their proteins before they can form shells. Others commit suicide upon infection, so as to avoid becoming an incubator for new viruses that would then kill their nearby relatives.
  • CRISPR genes can produce RNA molecules with a matching sequence. They grab onto the virus’s RNA and prevent them from being turned into proteins. The virus factory grinds to a halt.
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  • The bacteria hold onto an invading virus’s DNA, so that they are now prepared for a fresh attack. And over time, bacteria can build up little libraries of these virus barcodes. 
  • Last year, scientists at Indiana University surveyed the bacteria in people’s mouths and discovered 8,000 different viral barcodes–many of them corresponding to viruses scientists have yet to discover.
  • But if you build up a healthy store of antibodies to various strains of flu, smallpox, and other diseases, all that knowledge dies with you.
  • Not so for bacteria. When a microbe reproduces, it passes down its CRISPR genes and all of their viral barcodes to its descendants–including the ones it acquired in its own lifetime.
  • Last fall, for example, University of Cambridge scientists discovered viruses that carry an antidote for the suicide toxin made by their hosts. When the bacteria want to die, the virus forces them to live on. And just last month, University of Toronto scientists even discovered anti-CRISPR genes in viruses, which the viruses use to shut down the production of virus-killing molecules.
  • the scientists demonstrated that the ICP1 virus uses its CRISPR immune system to attack its host’s virus-attacking genes.
Casey Finnerty

'We Have a Limited Window of Opportunity': CDC Warns of Resistance 'Nightmare' | Wired ... - 0 views

  • “We have a very serious problem, and we need to sound an alarm.”
  • Healthcare institutions in 42 states have now identified at least one case of CRE. The occurrence of this resistance in the overall family of bacteria has risen at least four-fold over 10 years. In the CDC’s surveillance networks, 4.6 percent of hospitals and 17.8 percent of long-term care facilities diagnosed this bug in the first half of 2012.
  • CRE stands for “carbapenem-resistant Enterobacteriaceae.” Enterobacteriaceae are a family of more than 70 bacteria which share the characteristic of being gut-dwelling (“entero”)
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  • the CDC reviewed six steps that they first published last year in a CRE Toolkit and want health care facilities to take:
  • But an important point is that none of this is required, and none of this is funded.
  • There are no reimbursements, under Medicare, for infection-control as a hospital task
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    This article does a good job summarizing this week's announcement by the CDC director on the gravity of the CRE problem.
Tiffany Arcand

Onions and Flu - Can Raw Onions Prevent the Flu? - Urban Legends - 1 views

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    Although this article does not come from the most scholarly source, my dad and I were talking and he mentioned that if you slice an onion and place it in the corner of the room, it will "absorb" any flu virus present. This is not true.
Jeremiah Williamson

Severe Food Allergy Stresses Moms, Baffles Doctors - Yahoo! - 1 views

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    Going along with the immunology portion of class, this article talks about a new food allergy that a little boy suffers.  He is allergic to almost all food, except a handful of things.  it causes an immune response that is non-IgE, which is the case in most allergies.  
Nate Scheibe

Resistance to last-line antibiotic makes bacteria resistant to immune system - 0 views

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    An interesting article on cross-resistance.
Emma Radzak

Cold sores linked to cognitive decline - 1 views

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    The article says it may just be an interesting phenomenon. I found it interesting that the article pointed out that physical activity significantly reduces the infectious burden and cognitive decline, where if children stay physically active and maintain proper vaccination, it may decline the presence of cognitive decline.
Casey Finnerty

Panel Recommends HPV Vaccine for Boys and Young Men - NYTimes.com - 0 views

  • HPV infection is the most common sexually transmitted disease — between 75 percent and 80 percent of females and males in the United States will be infected at some point in their lives. Most will overcome the infection with no ill effects. But in some people, infections lead to cellular changes that cause warts or cancer, including cervical, vaginal and vulvar cancers in women and anal cancers in men and women. A growing body of evidence suggests that HPV also causes throat cancers in men and women as a result of oral sex. HPV infections cause about 15,000 cancers in women and 7,000 cancers in men each year. And while cervical cancer rates have plunged over the past four decades because of widespread screening, anal cancer rates in men and women have been increasing. Head and neck cancers have also been increasing, with the share associated with HPV infection increasing rapidly — perhaps because oral sex has increased in popularity.
Amy Jorgenson

In-package plasma process quickly, effectively kills bacteria - 0 views

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    If this is adapted for liquids, it could work wonders in areas with contaminated drinking water. However, the article also states that future research will examine food quality. My question is, why was that not researched before this article was released?
Tiffany Arcand

Good parenting vs. effective parenting on imgfave - 2 views

shared by Tiffany Arcand on 13 Apr 13 - No Cached
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    This is not scientific nor do I expect it to count towards my 10 articles, I just found it humorous and thought I would share :]
saraeberhardt

Donald R. Hopkins - How to Eradicate Guinea Worm Disease - NYTimes.com - 0 views

  • The strategy worked so well, Dr. Hopkins said, that Sierra Leone was smallpox-free in less than two years.
  • When programs are well run, he said, progress can be rapid; Ghana went from 501 cases to none in 18 months.
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    A positive article about the eradication of Guinea Worm Disease. Yet another source showing that vaccinations really do work. 
saraeberhardt

Nanosponges used to soak up toxins in the bloodstream - 0 views

  • the tiny sponges mimic red blood cells, and are able to soak up lethal toxins – including snake venom and bacteria – from the bloodstream.
  • The nanosponges are made up of a biocompatible polymer core, which is coated with segments of the host’s red blood cell membranes.
  • each nanosponge is 3,000 times smaller than a red blood cell
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  • So many of the nanosponges are injected that they end up actually outnumbering the real red blood cells in the bloodstream. This results in the majority of the toxins attaching themselves to the sponges, leaving most of the blood cells alone.
  • The project was led by Prof. Liangfang Zhang, and described in a paper recently published in the journal Nature Nanotechnology
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    As I'm working on my presentation, I came across this article. I thought it was very interesting considering what I'm presenting on releases two very potent toxins into the bloodstream and ultimately leads to death. 
Amy Jorgenson

Coccidioidomycosis-A Fungal Disease of the Americas - 0 views

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    This paper is an overview of Coccidioidomycosis. The explains the demographics, the life cycle, history, immunology, and treatment. The hope for a vaccine is also prevalent in this paper.  The paper summarizes Coccidioidomycosis and gives quick details about it.  Excellent paper on learning about the disease without diving in too deeply.
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    This article discusses the etiology and epidemiology of coccidiodiomycosis as well as the potential for a vaccine to treat the devastating symptoms brought about by this disease.
Casey Finnerty

Eggs, Too, May Provoke Bacteria to Raise Heart Risk - NYTimes.com - 0 views

  • The lecithin study, published Wednesday in The New England Journal of Medicine, is part of a growing appreciation of the role the body’s bacteria play in health and disease. With heart disease, investigators have long focused on the role of diet and heart disease, but expanding the scrutiny to bacteria adds a new dimension.
  • “Heart disease perhaps involves microbes in our gut,”
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    First carnitine and meat, now lecithin and eggs! Darn it! All things in moderation, I guess.
Samantha Mishall

ScienceDirect.com - Current Opinion in Microbiology - T cell responses to Chlamydia tra... - 0 views

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    An interesting paper about Chlamydia and the body's immune response against infection. Although the article doesn't discuss it, I believe further research could lead to development of a vaccine. A potential paper to use for our presentation.
Jeremiah Williamson

Salmonella outbreak prompts multi-state cucumber recall - Eatocracy - CNN.com Blogs - 0 views

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    17 states have reported illnesses due to this Salmonella outbreak. This is an awfully high number of states. The article shows ways to prevent salmonella, but many people fail to comply with the standard washing procedures.
Megan Goldman

A framework for human microbiome research : Nature : Nature Publishing Group - 0 views

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    A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project Consortium has established a population-scale framework to develop metagenomic protocols, resulting in a broad range of quality-controlled resources and data including standardized methods for creating, processing and interpreting distinct types of high-throughput metagenomic data available to the scientific community. An ambitious article found in another article I enjoyed reading. Was incredibly interested to find out that the vaginal microbiota of pregnant women was significantly different from non-pregnant and to find that these microbiota are preparing the soon to be born baby with it's own microbiota!! (http://www.nytimes.com/2012/06/19/science/studies-of-human-microbiome-yield-new-insights.html?ref=microbiology)
loryn_micro

ScienceDirect.com - The Veterinary Journal - Accuracy of a point-of-care ELISA test kit... - 0 views

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    Supplementary Journal Article for Presentation
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