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Matti Narkia

Vitamin D may curb diabetes - Pharmacy News - 0 views

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    A New Zealand study has found that South Asian women with insulin resistance improved markedly after taking vitamin D supplements

    Nutrition researcher Pamela von Hurst of the Institute of Food, Nutrition and Human Health at Albany, said while diet and exercise played a major part in the onset of type-2 diabetes, her findings reinforced the importance of vitamin D from the sun and supplements to prevent type-2 diabetes.

    Initial screening of 235 Auckland women from India, Pakistan and Sri Lanka aged 20 and older, revealed 47 per cent were insulin deficient and 84 per cent were vitamin D deficient. The 81 recruited for the study were split into two groups for a randomised controlled trial and given a vitamin D supplement or placebo. As well as an improvement in insulin resistance among those who took vitamin D for six months, Ms Von Hurst said post-menopausal women in the study also showed a reduced rate of bone breakdown.
Matti Narkia

Athletic Performance and Vitamin D : Medicine & Science in Sports & Exercise - 0 views

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    Athletic performance and vitamin D.
    Cannell JJ, Hollis BW, Sorenson MB, Taft TN, Anderson JJ.
    Med Sci Sports Exerc. 2009 May;41(5):1102-10. Review.
    PMID: 19346976
    doi: 10.1249/MSS.0b013e3181930c2b

    Conclusions: Vitamin D may improve athletic performance in vitamin D-deficient athletes. Peak athletic performance may occur when 25(OH)D levels approach those obtained by natural, full-body, summer sun exposure, which is at least 50 ng·mL-1. Such 25(OH)D levels may also protect the athlete from several acute and chronic medical conditions.
Matti Narkia

Correlation of symptoms with vitamin D deficiency and symptom response to cholecalcifer... - 0 views

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    Correlation of symptoms with vitamin D deficiency and symptom response to cholecalciferol treatment: a randomized controlled trial.
    Arvold DS, Odean MJ, Dornfeld MP, Regal RR, Arvold JG, Karwoski GC, Mast DJ, Sanford PB, Sjoberg RJ.
    Endocr Pract. 2009 May-Jun;15(3):203-12.
    PMID: 19364687

    Conclusions: Compared with participants in the placebo group, patients in the treatment group showed mild short-term improvement in the overall fibromyalgia impact score, but did not show significant improvement in most musculoskeletal symptoms or in activities of daily living.
Matti Narkia

Vitamin D receptor gene polymorphisms influence susceptibility to type 1 diabetes melli... - 0 views

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    Vitamin D receptor gene polymorphisms influence susceptibility to type 1 diabetes mellitus in the Taiwanese population.
    Chang TJ, Lei HH, Yeh JI, Chiu KC, Lee KC, Chen MC, Tai TY, Chuang LM.
    Clin Endocrinol (Oxf). 2000 May;52(5):575-80.
    PMID: 10792336
    DOI: 10.1046/j.1365-2265.2000.00985.x

    CONCLUSIONS

    Vitamin D receptor gene polymorphisms were associated with type 1 diabetes in a Taiwanese population. However, functional studies are needed to establish the role of the vitamin D receptor in the pathogenesis of type 1 diabetes mellitus.
Matti Narkia

Arch Gen Psychiatry -- Depression Is Associated With Decreased 25-Hydroxyvitamin D and ... - 0 views

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    Depression is associated with decreased 25-hydroxyvitamin D and increased parathyroid hormone levels in older adults.
    Hoogendijk WJ, Lips P, Dik MG, Deeg DJ, Beekman AT, Penninx BW.
    Arch Gen Psychiatry. 2008 May;65(5):508-12.
    PMID: 18458202

    Conclusion The results of this large population-based study show an association of depression status and severity with decreased serum 25(OH)D levels and increased serum PTH levels in older individuals.
Matti Narkia

Vitamin D Newsletter Mar 2006 | Dr. Wactawski-Wende, New England Journal of Medicine, a... - 0 views

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    "Good research is good for medicine. The only thing more important than good research is ethical research. The February 16th issue of the New England Journal of Medicine (NEJM) had a research paper on vitamin D and colon cancer. Was it good research? Was it ethical research? At stake are the lives of 36,000 older American women who agreed to participate in the Women's Health Initiative. "
Matti Narkia

Defining Adequate Vitamin D Intake : Cross-sectional and Intervention Studies - 0 views

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    Defining Adequate Vitamin D Intake : Cross-sectional and Intervention Studies
    Viljakainen, Heli Tuulikki
    University of Helsinki
    2008-05-23
    Doctoral dissertation (article-based)

    Vitamin D is required for normal bone growth and maintenance of the skeleton throughout life. In Finland, like in many other Western countries, the population suffers from inadequate or deficient vitamin D status, especially during winter, which is thought to increase the risk of osteoporosis. New strategies to prevent osteoporosis are actively being sought. The main objective of this thesis was to determine whether vitamin D is feasible in the primary prevention of osteoporosis; does it affect bone mineral accrual during the growth period? A second goal was to ascertain whether seasonal variation in calcitropic hormones affects bone remodelling, and to elucidate the vitamin D intake needed to overcome this variation in different age groups.

    In summary, vitamin D intake remains inadequate among the target groups of this thesis, as reflected by seasonal variation in calcitropic hormones and bone metabolism. Dietary intake of vitamin D should be increased to achieve at least an adequate vitamin D status (S-25-OHD>50 nmol/l) and possibly an optimal vitamin D status (S-25-OHD>80 nmol/l) throughout the year. This could be accomplished by introducing new vitamin D-fortified foods to the market."
Matti Narkia

Calcium and vitamin D intakes may be positively associated with brain lesions in depres... - 0 views

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    Calcium and vitamin D intakes may be positively associated with brain lesions in depressed and nondepressed elders.
    Payne ME, Anderson JJ, Steffens DC.
    Nutr Res. 2008 May;28(5):285-92.
    PMID: 19083421
    doi: 10.1016/j.nutres.2008.02.013

    In conclusion, calcium and vitamin D consumption were associated with brain lesions in elderly subjects even after controlling for potentially explanatory variables. These associations may be due to vascular calcification or other mechanism. The possibility of adverse effects of high intakes of calcium and vitamin D needs to be further explored in longitudinal studies of elderly subjects.
Matti Narkia

Aggressive Vitamin D Treatment for Osteoporosis - 0 views

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    "May 19, 2008 (Orlando, Florida) - A new study shows that a proactive vitamin D treatment plan should be considered when caring for all osteoporosis patients, and that such treatment might help decrease the likelihood of developing vitamin D deficiency.

    Vitamin D deficiency is widespread among patients being treated for osteoporosis, and such deficiency should be treated aggressively, according to the findings presented here at the American Association of Clinical Endocrinologists 17th Annual Meeting and Clinical Congress."
Matti Narkia

Serum Vitamin D and Risk of Prostate Cancer in a Case-Control Analysis Nested Within th... - 0 views

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    Serum vitamin D and risk of prostate cancer in a case-control analysis nested within the European Prospective Investigation into Cancer and Nutrition (EPIC).
    Travis RC, Crowe FL, Allen NE, Appleby PN, Roddam AW, Tjønneland A, Olsen A, Linseisen J, Kaaks R, Boeing H, Kröger J, Trichopoulou A, Dilis V, Trichopoulos D, Vineis P, Palli D, Tumino R, Sieri S, Bueno-de-Mesquita HB, van Duijnhoven FJ, Chirlaque MD, Barricarte A, Larrañaga N, González CA, Argüelles MV, Sánchez MJ, Stattin P, Hallmans G, Khaw KT, Bingham S, Rinaldi S, Slimani N, Jenab M, Riboli E, Key TJ.
    Am J Epidemiol. 2009 May 15;169(10):1223-32. Epub 2009 Apr 9.
    PMID: 19359375

    In summary, the results of this large nested case-control study provide no evidence in support of a protective effect of circulating concentrations of vitamin D on the risk of prostate cancer.
Matti Narkia

Food chain as origin of vitamin D in fish - ScienceDirect - Comparative Biochemistry an... - 0 views

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    Food chain as origin of vitamin D in fish
    D. Sunita Rao and N. Raghuramulu.
    Comparative Biochemistry and Physiology Part A: Physiology
    Volume 114, Issue 1, May 1996, Pages 15-19
    doi:10.1016/0300-9629(95)02024-1

    Plankton, the chief food source of fish, was assessed as the possible dietary origin of vitamin D in fish. The presence of vitamin D compounds were examined in fresh water phytoplankton and zooplankton employing a series of chromatographic procedures. Abundant amounts of provitamins D and vitamins D (D2 and D3) were found in the fresh water plankton. The high amount of vitamin D observed may be due to exposure of plankton to sunlight because the plankton were caught during the summer month. Thus, plankton may be an important contributor to vitamin D in fish.
Matti Narkia

Hypovitaminosis D is associated with insulin resistance and {beta} cell dysfunction -- ... - 0 views

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    Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction.
    Chiu KC, Chu A, Go VL, Saad MF.
    Am J Clin Nutr. 2004 May;79(5):820-5.
    PMID: 15113720

    Conclusions: The data show a positive correlation of 25(OH)D concentration with insulin sensitivity and a negative effect of hypovitaminosis D on ß cell function. Subjects with hypovitaminosis D are at higher risk of insulin resistance and the metabolic syndrome. Further studies are required to explore the underlying mechanisms.
Matti Narkia

Vitamin D Receptor Expression in Normal, Premalignant, and Malignant Human Lung Tissue ... - 0 views

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    Vitamin D receptor expression in normal, premalignant, and malignant human lung tissue.
    Menezes RJ, Cheney RT, Husain A, Tretiakova M, Loewen G, Johnson CS, Jayaprakash V, Moysich KB, Salgia R, Reid ME.
    Cancer Epidemiol Biomarkers Prev. 2008 May;17(5):1104-10.
    PMID: 18483332
    doi: 10.1158/1055-9965.EPI-07-2713

    onclusions: VDR expression spanned the lung carcinogenesis spectrum. Nuclear expression was similar across various histologies, whereas cytoplasmic expression decreased with increasing histologic grade. These results indicate that there is potential for the use of calcitriol as a chemopreventive agent against the development of lung cancer. (Cancer Epidemiol Biomarkers Prev 2008;17(5):1104-10)
Matti Narkia

Vitamin D in Cancer Patients: Above All, Do No Harm -- Goodwin 27 (13): 2117 -- Journal... - 0 views

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    Vitamin D in cancer patients: above all, do no harm.
    Goodwin PJ.
    J Clin Oncol. 2009 May 1;27(13):2117-9. Epub 2009 Apr 6.
    PMID: 19349538
Matti Narkia

Serum 25-hydroxyvitamin D status of vegetarians, partial vegetarians, and nonvegetarian... - 0 views

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    Serum 25-hydroxyvitamin D status of vegetarians, partial vegetarians, and nonvegetarians: the Adventist Health Study-2.
    Chan J, Jaceldo-Siegl K, Fraser GE.
    Am J Clin Nutr. 2009 May;89(5):1686S-1692S. Epub 2009 Apr 1.
    PMID: 19339396

    Conclusions: s25(OH)D concentrations were not associated with vegetarian status. Other factors, such as vitamin D supplementation, degree of skin pigmentation, and amount and intensity of sun exposure have greater influence on s25(OH)D than does diet.
Matti Narkia

Calcium and vitamin d supplementation decreases incidence of stress fractures in female... - 0 views

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    Calcium and vitamin d supplementation decreases incidence of stress fractures in female navy recruits.
    Lappe J, Cullen D, Haynatzki G, Recker R, Ahlf R, Thompson K.
    J Bone Miner Res. 2008 May;23(5):741-9.
    PMID: 18433305
    doi: 10.1359/jbmr.080102

    Conclusions: Generalizing the findings to the population of 14,416 women who entered basic training at the Great Lakes during the 24 mo of recruitment, calcium and vitamin D supplementation for the entire cohort would have prevented 187 persons from fracturing. Such a decrease in SFx would be associated with a significant decrease in morbidity and financial costs.
Matti Narkia

An outbreak of hypervitaminosis D associated with the overfortification of milk from a ... - 0 views

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    An outbreak of hypervitaminosis D associated with the overfortification of milk from a home-delivery dairy.
    Blank S, Scanlon KS, Sinks TH, Lett S, Falk H.
    Am J Public Health. 1995 May;85(5):656-9.
    PMID: 7733425
Matti Narkia

New Research by D*action Member Dr. Cedric Garland Suggests Role Low Levels of Vitamin ... - 0 views

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    San Diego, CA (PRWEB) May 25, 2009 -- Coming on the heels of the publishing in the Annals of Epidemiology of a new study led by Dr. Cedric Garland, on the preventive measures of vitamin D, GrassrootsHealth D*action Project is calling on physicians, health clinics and groups throughout the country to recognize the need for determining vitamin D levels and to ensure the public have their blood levels of vitamin D tested.

    According to research from the newly published study by Cedric F. Garland, Dr. P.H., FACE, Department of Family and Preventive Medicine and Moores Cancer Center of the University of California, San Diego (UCSD), "It is projected that raising the minimum year-around serum 25(OH)D level to 40-60 ng/ml (100-150 nmol/L) would prevent approximately 58,000 new cases of breast cancer and 49,000 new cases of colorectal cancer each year, and three quarters of deaths from these diseases, in the US and Canada."
Matti Narkia

Vitamin D Levels Linked to Breast-Cancer Prognosis - GrassrootsHealth | Vitamin D Action - 0 views

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    Women who are vitamin D deficient when they are diagnosed with breast cancer are more likely to have their disease spread and are more likely to die than women who have adequate vitamin D levels, new Canadian research says.

    The study found that women who were vitamin D deficient were 94 per cent more likely to have their cancer metastasize (spread) and 73 per cent more likely to die.

    The research was led by Dr. Pamela Goodwin, a breast cancer researcher at Mount Sinai Hospital in Toronto. The study analyzed blood samples and disease outcome from more than 500 women diagnosed with breast cancer between 1989 and 1995. Women were followed up for an average of 11 years.
Matti Narkia

JAMA -- Fracture Prevention With Vitamin D Supplementation: A Meta-analysis of Randomiz... - 0 views

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    Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials.
    Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-Hughes B.
    JAMA. 2005 May 11;293(18):2257-64. Review.
    PMID: 15886381

    Conclusions Oral vitamin D supplementation between 700 to 800 IU/d appears to reduce the risk of hip and any nonvertebral fractures in ambulatory or institutionalized elderly persons. An oral vitamin D dose of 400 IU/d is not sufficient for fracture prevention.
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