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Vitamin D and diabetes: improvement of glycemic control with vitamin D3 repletion. Schwalfenberg G. Can Fam Physician. 2008 Jun;54(6):864-6. PMID: 18556494 Conclusion These cases support information that is already known about VTD and its effect on the islet cell. As discussed above, this might be true only for vitamin D3 and not vitamin D2, although vitamin D2 has been shown to improve bone health. Vitamin D insufficiency or deficiency is common, and repletion might improve glycemic control early in type 2 diabetes. Diabetes is one of the fastest growing chronic diseases worldwide. Vitamin D3 is inexpensive and readily available. Well-designed clinical studies are required to ascertain if improving 25(OH)D levels from an insufficiency or deficiency to sufficiency improves glycemic control in diabetes. These studies need to be properly designed: a randomized controlled trial with VTD deficiency or insufficiency identified in diabetic patients of various ethnic

Serum levels of free 1,25-dihydroxyvitamin D in vitamin D toxicity. Pettifor JM, Bikle DD, Cavaleros M, Zachen D, Kamdar MC, Ross FP. Ann Intern Med. 1995 Apr 1;122(7):511-3. PMID: 7872586 CONCLUSIONS: Although the patients had normal or near-normal total 1,25-(OH)2D values, most patients had elevated free 1,25-(OH)2D levels. These findings suggest that elevated free 1,25-(OH)2D levels might play a role in the pathogenesis of hypercalcemia in vitamin D toxicity.

A family with massive acute vitamin D intoxication. Down PF, Polak A, Regan RJ. Postgrad Med J. 1979 Dec;55(654):897-902. PMID: 232912

Vitamin D intoxication associated with an over-the-counter supplement. Koutkia P, Chen TC, Holick MF. N Engl J Med. 2001 Jul 5;345(1):66-7. PMID: 11439958

Acute vitamin D intoxication in a child. Barrueto F Jr, Wang-Flores HH, Howland MA, Hoffman RS, Nelson LS. Pediatrics. 2005 Sep;116(3):e453-6. PMID: 16140692

[Severe hypercalcemia due to vitamin D intoxication] Chambellan-Tison C, Horen B, Plat-Wilson G, Moulin P, Claudet I. Arch Pediatr. 2007 Nov;14(11):1328-32. Epub 2007 Oct 10. French. PMID: 17931839

Hypercalcemia due to Hypervitaminosis D: Report of Seven Patients. Joshi R. J Trop Pediatr. 2009 Apr 1. [Epub ahead of print] PMID: 19339514

Unusually prolonged vitamin D intoxication after discontinuation of vitamin D: possible role of primary hyperparathyroidism. Taskapan H, Vieth R, Oreopoulos DG. Int Urol Nephrol. 2008;40(3):801-5. Epub 2008 Jun 5. PMID: 18528779 DOI: 10.1007/s11255-008-9404-1

Vitamin D poisoning by table sugar. Vieth R, Pinto TR, Reen BS, Wong MM. Lancet. 2002 Feb 23;359(9307):672. PMID: 11879864 doi:10.1016/S0140-6736(02)07814-5

Improvement of chronic back pain or failed back surgery with vitamin D repletion: a case series.\nSchwalfenberg G.\nJ Am Board Fam Med. 2009 Jan-Feb;22(1):69-74.\nPMID: 19124636

Vitamin D replacement in Asians with diabetes may increase insulin resistance. Taylor AV, Wise PH. Postgrad Med J. 1998 Jun;74(872):365-6. PMID: 9799895 We report three cases of vitamin D replacement in British Asians with vitamin D deficiency and non-insulin-dependent diabetes mellitus. In all cases, replacement resulted in an increase in insulin resistance and a deterioration of glycaemic control