Obesity - Leptin Resistance and Obesity - 0 views
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Nathan Goodyear on 09 Mar 11another great review on Leptin Resistance and obesity
Inflammation: the link between insulin resistance, obesity and diabetes
Leptin resistance is associated with extreme obesity and aggregates in families - 0 views
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leptin resistance and obesity
ScienceDirect - Physiology & Behavior : The role of leptin in leptin resistance and obe... - 0 views
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The role of leptin in leptin resistance and obesity
ScienceDirect - Trends in Immunology : Inflammation: the link between insulin resistanc... - 0 views
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Chronic overnutrition (obesity) might thus be a proinflammatory state with oxidative stress. Secondly, the increased concentrations of TNF-α and IL-6, associated with obesity and type 2 diabetes, might interfere with insulin action by suppressing insulin signal transduction. This might interfere with the anti-inflammatory effect of insulin, which in turn might promote inflammation.
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Inflammation: the link between insulin resistance, obesity and diabetes
Leptin stimulates fatty-acid oxidation by activati... [Nature. 2002] - PubMed result - 0 views
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Leptin is a hormone secreted by adipocytes that plays a pivotal role in regulating food intake, energy expenditure and neuroendocrine function. Leptin stimulates the oxidation of fatty acids and the uptake of glucose, and prevents the accumulation of lipids in nonadipose tissues, which can lead to functional impairments known as "lipotoxicity"
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Leptin and fat accumulation called "lipotoxicity"
Leptin: a novel therapeutic role in lipodystrophy - 0 views
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more on leptin and its physiologic role in metabolic dysfunction
Type 1 diabetes associated with acquired generaliz... [J Clin Endocrinol Metab. 2008] -... - 0 views
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Acquired generalized lipodystrophy (AGL) is marked by severe insulin resistance and hypertriglyceridemia. Rarely, AGL and type 1 diabetes (T1D) coexist.
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Long-term recombinant leptin therapy is effective in treating the insulin resistance of patients with the unusual combination of T1D and AGL.
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leptin useful in severe insulin resistance, hypertriglyceridemia and type 1 Diabetes
The clinical efficacy of the adipocyte-derived hor... [Arch Physiol Biochem. 2006] - Pu... - 0 views
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In hypoleptinemic patients with lipodystrophy, there is a dramatic improvement in glucose metabolism, dyslipidemia and hepatic steatosis
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leptin helps to correct metabolic dysfunction
Associations between fluorosis of permanent inciso... [J Am Dent Assoc. 2010] - PubMed ... - 0 views
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ADA warns against flouride use
Benzodiazepines inhibit thyrotropin (TSH)-releasin... [Endocrinology. 1986] - PubMed re... - 0 views
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benzodiazepines inhibit TSH secretion
Effect of metoclopramide--a dopaminergic blocker a... [Acta Endocrinol (Copenh). 1985] ... - 0 views
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High levels of cortisol may be responsible for the altered TT4 peripheral metabolism to TT3 and rT3 in these patients.
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elevated cortisol blocks T4 to T3 conversion and increases rT3 production
SpringerLink - Wiener Klinische Wochenschrift, Volume 117, Number 18 - 0 views
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TSH not the best marker to follow in thyroid replacement therapy
Thyroid Insufficiency. Is TSH Measurement the Only Diagnostic Tool? | DeepDyve - Resear... - 0 views
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In study of 832 clients, TSH poorly correlated with hypothyroidism
Antidepressants, Metabolic Syndrome May Be Tied : Family Practice News - 0 views
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antidepressants correlated with metabolic syndrome
Articles - TSH, temperature, pulse rate, and other indicators in hypothyroidism - 0 views
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long. But great post on the dynamics of thyroid function. Linear thinking can not apply
Autoimmunity and Heavy Metals - 0 views
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Gold may cause autoimmune thrombocytopenia, immune complex-mediated glomerulonephritis and other autoimmune disorders
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there is solid evidence that mercury can induce autoimmune disease both in humans and experimental animals.
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Heavy metals cause some autoimmune diseases
Pathogenesis of lead-induced hypertension: role of... [J Hypertens Suppl. 2002] - PubMe... - 0 views
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Chronic exposure to low levels of lead causes hypertension in humans and experimental animals
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Lead-induced hypertension
Lead-induced hypertension: role of oxidative stres... [Curr Hypertens Rep. 2004] - PubM... - 0 views
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Chronic, low-level lead exposure causes hypertension in both animals and humans.
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lead-induced hypertension
Blood Lead Is a Predictor of Homocysteine Levels in a Population-Based Study of Older A... - 0 views
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These results suggest that homocysteine could be a mechanism that underlies the effects of lead on the cardiovascular and central nervous systems
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your elevated homocysteine maybe be just a marker for elevated lead
ScienceDirect - Molecular Immunology : Mechanisms of heavy metal-induced autoimmunity - 0 views
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Mechanisms of heavy metal-induced autoimmunity
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Heavy metals and autoimmune disease
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