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Boswellia ovalifoliolata abrogates ROS mediated NF-κB activation, causes apop... - 0 views

pubmed.ncbi.nlm.nih.gov/24908637 triple negative breast cancer Boswellia TNBC chemotherapy
shared by Nathan Goodyear on 30 Apr 21 - No Cached
  • Nathan Goodyear on 30 Apr 21
     
    Boswellia shows chemosensitizing effects with doxorubicin and cisplatin with TNBC.
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Quercetin Inhibits the Proliferation and Metastasis of Human Non-Small Cell L... - 0 views

www.ncbi.nlm.nih.gov/...PMC7144538 Src Quercetin cancer NF-kappaB
shared by Nathan Goodyear on 20 May 21 - No Cached
  • Nathan Goodyear on 20 May 21
     
    Quercetin inhibits NF-kappaB through src suppression.
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Abscopal antitumor immune effects of magnet-mediated hyperthermia at a high therapeutic... - 0 views

www.ncbi.nlm.nih.gov/...PMC3919910 cancer abscopal effect hyperthermia
shared by Nathan Goodyear on 25 Jan 21 - No Cached
  • Nathan Goodyear on 25 Jan 21
     
    Local hyperthermia stimulates distal tumor death via abscopal effects.
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Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mecha... - 0 views

stm.sciencemag.org/...eaan0026 chemotherapy TMEM tumor microenvironment of metastasis metastasis cancer
shared by Nathan Goodyear on 11 Jul 17 - No Cached
  • We found about a twofold increase in circulating tumor cells (CTCs) (P < 0.05) after paclitaxel treatment in all experimental models examined
  • We found an increase in both the metastatic incidence (at least one micrometastatic focus of more than five tumor cells) (Fig. 3I) and the number of cancer cell micrometastases in the lungs of paclitaxel-treated mice
  • in early-stage breast cancers, chemotherapy increases vascular permeability at TMEM sites, which is accompanied by increased cancer cell dissemination.
  • ...1 more annotation...
  • significant ~1.3-fold (P = 0.027) increase in the number of CTCs
  • Nathan Goodyear on 11 Jul 17
     
    New study suggests chemotherapy may increase metastasis  via increase in TMEM.  I wonder if this increases recurrence as well.  Could the very corner stone of Cancer therapy actually increase metastatic risk potential?
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Premetastatic milieu explained by TLR4 agonist-mediated homeostatic inflammation - 0 views

www.ncbi.nlm.nih.gov/...PMC4001895 metastasis TLRs cancer TLR toll-like receptors TLR4
shared by Nathan Goodyear on 22 Aug 20 - No Cached
  • Nathan Goodyear on 22 Aug 20
     
    To be read
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Artemisinin sensitizes tumor cells to NK cell-mediated cytolysis - ScienceDirect - 0 views

www.sciencedirect.com/...S0006291X20301637 cancer artemisinin NK cells
shared by Nathan Goodyear on 22 Aug 20 - No Cached
  • Nathan Goodyear on 22 Aug 20
     
    Artemisinin increases tumor cell sensitivity to NK cell killing activity.
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Ferritin induction protects cortical astrocytes from heme-mediated oxidative injury - S... - 0 views

www.sciencedirect.com/...S0306452202002439 ROS ferritin HO-1 heme-oxygenase-1
shared by Nathan Goodyear on 24 May 20 - No Cached
  • Nathan Goodyear on 24 May 20
     
    HO-1 induces increase in ferritin to reduce ROS
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Molecular mechanism and functional consequences of lansoprazole-mediated heme oxygenase... - 0 views

www.ncbi.nlm.nih.gov/...PMC2747059 ferritin heme-oxygenase-1 HO-1 ROS
shared by Nathan Goodyear on 24 May 20 - No Cached
  • Nathan Goodyear on 24 May 20
     
    HO-1 and thus increase in ferritin induction by lansoprozole reduces ROS.
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Editorial: Cytokine-Mediated Organ Dysfunction and Tissue Damage Induced by Viruses - 1 views

www.ncbi.nlm.nih.gov/...PMC6987404 influenza TLR4 cytokine storm cytokines
shared by Nathan Goodyear on 14 May 20 - No Cached
  • Nathan Goodyear on 14 May 20
     
    Influenza and other virus' induce cytokine production i.e. cytokine storm via TLR
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