Skip to main content

Home/ Dr. Goodyear/ Group items matching "symptome" in title, tags, annotations or url

Group items matching
in title, tags, annotations or url

Sort By: Relevance | Date Filter: All | Bookmarks | Topics Simple Middle
1More

Symptoms in advanced cancer: relationship to endogenous cortisol levels - 0 views

  •  
    In people with cancer, increasing cortisol levels associated with increasing symptoms
24More

Review of health risks of low testosterone and testosterone administration - 0 views

  • Hypogonadism may be defined either as serum concentration of T (either total T, bioavailable T or free T) or as low T plus symptoms of hypogonadism
  • The Baltimore Longitudinal Study on Aging reported the incidence of total serum T < 325 ng/dL to be 20% for men in their 60s, 30% for men in their 70s and 50% for men over 80
  • The Massachusetts Aging Male Study reported that 12.3% of men aged 40 to 70 had a total serum T of < 200 ng/dL with 3 or more symptoms of hypogonadism
  • ...19 more annotations...
  • The Boston Area Community Health Study reported that 5.6% of men aged 30 to 70 were hypogonadal, as defined by total serum T < 300 ng/dL; or, free serum T < 5 ng/dL plus 3 or more symptoms of hypogonadism
  • In a health screening project among 819 men in Taiwan, the prevalence of hypogonadism (total serum T < 300 ng/dL) ranged from 16.5% for men in their 40s, 23.0% for men in their 50s, 28.9% for men in their 60s, and 37.2% for men older than 70 years of age
  • The prevalence of hypogonadism among men in Taiwan is higher than the prevalence reported in the Massachusetts Male Aging Study
  • CAG repeat sequence, within the androgen receptor (AR). Rajender et al[12] reviewed over 30 studies on the AR trinucleotide repeat and infertility
  • suggestion that CAG repeat length may determine androgen responsiveness, this issue is not clearly settled
  • reported prevalence of low T in older men range from 5.6% to 50%
  • Those in the hypogonadal group (n = 4269) had direct health care costs, that exceeded the eugonadal group (n = 4269) by an average of $7100 over the course of the observation window
  • higher economic burden and presence of co-morbidities for hypogonadism
  • minor to moderate improvements in lean mass and muscle strength
  • increased bone mineral density
  • modest enhancement in sexual function
  • reduced adiposity
  • lessening of depressive symptoms
  • Meta-analyses of clinical TRT trials as of 2010 have identified three major adverse events resulting from TRT: (1) polycythemia; (2) an increase in prostate-related events; and (3) and a slight reduction in serum high-density lipoprotein (HDL) cholesterol
  • polycythemia (> 3.5-fold increase in risk
  • TRT produced a 40% prostate enlargement in older hypogonadal male Veterans over 12 mo
  • no published analysis has reported measurable increases in prostate cancer risk or Gleason score in men undergoing TRT, or in hypogonadal men with a history of prostate cancer undergoing TRT
  • the prostate which highly expresses the type II 5α-reductase enzyme. Inhibition of this enzyme via finasteride (a type II 5α-reductase inhibitor) or dutasteride (a dual type I and II 5α-reductase inhibitor) reduces circulating DHT 50%-75% and > 90%, respectively[47], and reduces prostate mass[48] and prostate cancer risk
  • Normally estradiol partially regulates testosterone levels, at the hypothalamus, blunting LH and FSH release from the pituitary. As a selective estrogen receptor modulator, CC interrupts this pathway, and consequently there is a greater stimulation for the production of testosterone in Leydig cells
    • Nathan Goodyear
       
      this would only apply if E1 and/or E2 levels were elevated, which the authors make no mention of.
  •  
    to be read
35More

Elderly men over 65 years of age with late-onset hypogonadism benefit as much from test... - 0 views

  • The benefits of restoring serum testosterone in men with LOH were not significantly different between men older than 65 years of age and younger men. There were no indications that side effects were more severe in elderly men. The effects on prostate and urinary function and hematocrit were within safe margins.
  • obesity, but also impaired general health, are the more common causes of low testosterone in aging men
  • Severe LOH is associated with substantially higher risks of all-cause and cardiovascular mortality,
  • ...30 more annotations...
  • advanced age, obesity, a diagnosis of metabolic syndrome, and poor general health status were predictors of LOH
  • Diabetes mellitus was correlated with hypogonadism in most studies
  • coronary heart disease, hypertension, stroke, and peripheral arterial disease did not predict hypogonadism, they did correlate with the incidence of low testosterone
  • LOH can be defined by the presence of at least three sexual symptoms associated with a total testosterone level of less than 11 nmol/L (3.2 ng/mL) and a free testosterone level of less than 220 pmol/L (64 pg/mL)
    • Nathan Goodyear
       
      the European Male Aging study defined low T as total < 320 ng/dl and free < 64 pg/ml.  
  • Mean weight decreased
  • Waist circumference decreased
  • Total cholesterol decreased
  • Low-density lipoprotein decreased
  • Triglycerides decreased
  • High-density lipoprotein (HDL) increased
  • ratio of total cholesterol to HDL improved
  • Prostate volume increased
  • PSA increased
  • The benefits for men older than 65 years of age were compared with those of younger men, and the improvements in body weight, metabolic factors, psychological functioning, and sexual functioning were of the same magnitude in both age groups
  • weight loss was progressive over the 6-year period, effects of testosterone on lipids and on psychological and sexual functioning reached a plateau after approximately 3 years and these effects were sustained
  • Effects of testosterone on hematopoiesis, on the prostate, and on bladder function were not more severe in older men than in younger men
  • observe a mild increase in prostate volume and serum PSA over time, which is a normal finding in aging men. Maybe somewhat surprising, postvoiding residue and the IPSS did not deteriorate with aging but showed a degree of improvement
  • the severity of the metabolic syndrome is associated with the severity of lower urinary tract symptoms
  • The symptoms of the metabolic syndrome improve upon testosterone treatment and testosterone may thus have a favorable effect on lower urinary tract symptoms
  • it seems reasonable to conclude that the risks of testosterone administration to elderly men are not disproportionately higher in elderly men than in younger men.
  • Despite evidence to the contrary, physicians still harbor a wrongful association between testosterone and the development of prostate pathology (prostate cancer and benign prostate hyperplasia)
  • Not surprisingly, the incidence of prostate cancer was higher in older men; however, it was lower than expected in both groups
  • These observations suggest that the incidence of prostate cancer in patients receiving testosterone therapy, both in the younger and in the older group, was not greater than in the general population not receiving testosterone treatment
  • The historical fear that raising testosterone levels will result in more prostate cancer has been dispelled, particularly by the work of Abraham Morgentaler
  • Higher serum testosterone levels fail to show an increased risk of prostate cancer, and supraphysiological testosterone does not increase prostate volume or PSA in healthy men
  • This apparent paradox is explained by the "saturation model,"
  • Recent studies indicate no increased risk of prostate cancer among men with serum testosterone in the therapeutic range
  • In the present observational study, no cases of major adverse cardiovascular events occurred.
  • the benefits of testosterone therapy are fully achieved only by long-term treatment
  • To achieve maximal benefits, good patient adherence is a prerequisite
  •  
    Study finds new difference in Testosterone benefits and/or side effects between men < 65 with low T and men > 65 with low T.
1More

ALCAT Test results in the treatment of respiratory... [Rocz Akad Med Bialymst. 1995] - ... - 0 views

  •  
    ALCAT Test shown to reduce arthritis, hives, bronchitis, and GI symptoms as well as other symptoms
1More

Probiotic Effects on Cold and Influenza-Like Symptom Incidence and Duration in Children - 0 views

  •  
    probioitics in children found to decrease the incidence of cold symptoms.  Effective preventative measure for chldren.
1More

Arch Intern Med -- Abstract: Soy Isoflavones in the Prevention of Menopausal Bone Loss ... - 0 views

  •  
    Soy not shown to reduce menopausal symptoms in recent study
1More

Probiotic Effects on Cold and Influenza-Like Symptom Incidence and Duration in Children - 0 views

  •  
    probiotics shown to beneficial in cold and flu symptoms
5More

Wiley Online Library: Book Abstract - 0 views

  • In the relatively uncommon circumstance of vaccine matching the viral circulating strain and high circulation, 4% of unvaccinated people versus 1% of vaccinated people developed influenza symptoms (risk difference (RD) 3%
  • The corresponding figures for poor vaccine matching were 2% and 1% (RD 1, 95% CI 0% to 3%).
  • Vaccination had a modest effect on time off work and had no effect on hospital admissions or complication rates
  • ...1 more annotation...
  • Influenza vaccines have a modest effect in reducing influenza symptoms and working days lost. There is no evidence that they affect complications, such as pneumonia, or transmission.
  •  
    exhaustive review of the flu vaccine data reveals VERY poor matching of vaccine, poor prevention of flu symptoms, and only modest effect on reduction in hospital admission or complication rates.   Final conclusion: "There is no evidence that they affect complications, such as pneumonia, or TRANSMISSION.
1More

http://press.endocrine.org/doi/pdf/10.1210/jc.2014-1872 - 0 views

  •  
    New study finds Testosterone therapy provides less than statistical significant improvement in constitutional/sexual symptoms, in obese men with type II diabetes with symptoms classified as mild-moderate with modest reductions in Total Testosterone.  This study highlights that low Testosterone is a biomarker of poor health and multiple comorbidities and that simply adding in Testosterone therapy will not cure all male woes.  The authors did state that ED and low T are separate issues and I will differ with them on this--they are in fact link.  This association may vary between individuals, but to flatly state they are completely separate issues is devoid of the fact that testosterone has been shown to reduce inflammatory cytokines and improve PDE5 therapy.  
1More

Red alert for women's heart: the urgent need for more research and knowledge on cardiov... - 0 views

  •  
    Vasomotor symptoms (hot flashes and night sweats) is associated with increased cardiovascular risk in women.
1More

Hay Fever Symptoms | Hay Fever Injection | Hay Fever Treatment - 0 views

  •  
    Between 10-15% of us suffer from hay fever symptoms. For many people it causes significant fatigue and problems with concentration and alertness. Of those 10-15% of people with hay-fever, about 10% do not respond to conventional, easily available treatments like anti-histamine tablets, nasal sprays and eye drops.
1More

Causes And Symptoms Of PCOS | Your Health Our Priority - 0 views

  •  
    PCOS is a disease of the female reproductive system that is characterized by hairiness, infrequent or heavy periods, skin disorders and infertility. Its symptoms and causes need immediate medical care as it can be deadly.
1More

Symptoms Of Iron Deficiency | Your Health Our Priority - 0 views

  •  
    Iron deficiency is the most common mineral deficiency in the US. It affects women mostly with symptoms ranging from an inflamed tongue to a strong craving for undesirable food items. It can be cured through proper treatment and healthy diet.
1More

Down Syndrome: Symptoms, Types &amp; Treatment | Health Blog - 0 views

  •  
    Down syndrome is also known as DS or DNS. This is a genetic disorder. Our human body is made of millions of cells.
2More

Psoriasis: Causes, Symptoms, Types &amp; Treatment - Health Blog - 0 views

  •  
    Psoriasis is a chronic skin condition that accelerates the rate at which your skin cells grow. An effective method to treat psoriasis is phototherapy or light therapy.
  •  
    Psoriasis is an auto-immune illness that affects almost three percent of the world's population. People who suffer from psoriasis experience a great deal of skin irritation and discomfort.
1More

https://www.thefastleanpro.us/ - 0 views

  •  
    Fast Lean Pro™ (official) | weight lose Formula thefastleanpro.us · by Fast Lean Pro Fast Lean Pro Only $49/Bottle Limited Time Offer! Fast Lean Pro Special Deal + Special 51% Discount Save $300 + 180 Days Money Back Guarantee FastLeanPro The #1 Solution To natural metabolism booster helps you lose weight quickly without starving yourself. Fast Lean Pro is a natural powder supplement for weight loss that has recently been developed by Japanese scientists. Regular Price: $99/per bottle Only for: $49/per bottle What Is Fast Lean Pro? Fast Lean Pro is a powdered dietary powdery supplement designed to aid in weight loss. It contains a unique combination of ingredients that are believed to activate the body's "fasting switch" to optimize results. This product focuses not only on weight loss but also on promoting cellular rejuvenation, fasting, and a healthy metabolism. The concept behind Fast Lean Pro is that incorporating fasting into one's lifestyle can lead to positive outcomes irrespective of individual food choices and eating habits. To comprehend the mechanism of the Fast Lean Pro process, it is necessary to delve into its specific details. One of the few weight loss pills on the market that contains Fibersol is Fast Lean Pro. This safe, specialized fiber adds bulk to its weight when combined with water, curbing your appetite before it throws off your meal plan. If you're trying to lose weight or curb your appetite, Fast Lean Pro can help. Supporting substances such as niacin and chromium contribute to this. The body can further benefit from these nutrients, such as through improved metabolic regulation. Fast lean Pro is non-GMO, vegan friendly, and contains no artificial ingredients or stimulants. Fast Lean Pro is a weight loss product that promotes the body's natural self-feeding process. The body naturally removes old, damaged cells through a process known as autophagy to encourage cell regeneration and repair. Recent studies by a group
1More

Insomnia What You Know and What You Don't! - 0 views

  •  
    Most of you would know that insomnia is a sleep problem, and it causes difficulty in falling asleep and staying asleep for a reasonable amount of time. It also affects sleep quality, resulting in daytime inactivity. Most of the time, insomnia can become long-term. This long-term insomnia is called chronic insomnia. This type of insomnia is diagnosed when the patient has trouble sleeping, at least 3 to 4 days a week for at least one month. Acute insomnia or short-term insomnia is the most common type of insomnia that most people have today. As the name suggests, it is a short-term illness and lasts only for a few days or at most three to four weeks. Consult your doctor, get a proper check-up, explain all the problems including your sleep schedule. Initially, severe insomnia symptoms may not require adequate treatment. If a person feels tired and cannot perform his physical activities during the day, he should buy sleeping pills for a short time as per the prescription of his doctor or physician. If your symptoms are not under control, use cheap Temazepam 10 mg tablets available online. You can buy these insomnia pills online from Pharma Health Online.
1More

JAMA Network | JAMA Neurology | Refractory Nonmotor Symptoms in Male Patients With Park... - 0 views

  •  
    Testosterone therapy aids symptoms of Parkinson's disease.  Whether low T is an associated finding or plays a role has yet to be determined.  However, we do know that androgens play an anti-inflammatory role in men and we know that inflammation plays a role in the neurodegenerative disease that is Parkinson's disease.
1More

Low Free Testosterone Is Associated with Hypogonadal Signs and Symptoms in Men with Nor... - 0 views

  •  
    low free Testosterone, though calculated in this study, found to be associated with low T symptoms despite normal total Testosterone.  Though the "normal" total Testosterone in this study is abnormal low in other studies.  Only abstract available.
2More

Home Remedies for Sore Throat - 0 views

  •  
    A Sore Throat is a painful feeling in the throat aggravated by swallowing. A sore throat can also feel dry and scratchy and  makes it hard to talk. A sore throat is a frequent symptom of the common cold or other acute respiratory tract ...
  •  
    A Sore Throat is a painful feeling in the throat aggravated by swallowing. A sore throat can also feel dry and scratchy and  makes it hard to talk. A sore throat is a frequent symptom of the common cold or other acute respiratory tract ...
‹ Previous 21 - 40 of 283 Next › Last »
Showing 20 items per page