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Contents contributed and discussions participated by Nathan Goodyear

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Nathan Goodyear

Thyroid Hormone Replacement - One Hormone or Two? - NEJM - 0 views

www.nejm.org/...NEJM199902113400611

thyroid T4 T3 armour

shared by Nathan Goodyear on 17 Dec 10 - No Cached
  • Nathan Goodyear on 17 Dec 10
     
    Patients feel better taking both T4 and T3 compared to those taking just T4
Nathan Goodyear

Long-lived mitochondrial (Mit) mutants of Caenorhabditis elegans utilize a novel metabo... - 0 views

www.fasebj.org/4977

mitochondria metabolism aging

shared by Nathan Goodyear on 16 Dec 10 - No Cached
  • Our study suggests long-lived, genetically specified Mit mutants employ a novel metabolism and that life span may well arise as a function of metabolic state.
  • Nathan Goodyear on 16 Dec 10
     
    Mitchondria, metabolism,  and aging
Nathan Goodyear

Clinical controversies in screening women for thyr... [J Midwifery Womens Health. 2006 ... - 0 views

www.ncbi.nlm.nih.gov/...16647667

TSH screening

shared by Nathan Goodyear on 16 Dec 10 - No Cached
  • In November 2002, the American Association of Clinical Endocrinologists (AACE) released new guidelines for clinical practice for the diagnosis and treatment of hyperthyroidism and hypothyroidism, which includes a new thyroid-stimulating hormone (TSH) reference range of 0.3 to 3.0 mIU/
  • Nathan Goodyear on 16 Dec 10
     
    TSH "screening" needs to be between 0.3 and 3 according to American Association of Clinical Endocrinologists
Nathan Goodyear

Subclinical Thyroid Dysfunction: A Joint Statement on Management from the American Asso... - 0 views

jcem.endojournals.org/...581

thyroid hypothyroidism subclinical

shared by Nathan Goodyear on 16 Dec 10 - No Cached
  • the potential benefits of early detection and treatment of subclinical thyroid dysfunction significantly outweigh the potential side-effects that could result from early diagnosis and therapy
  • Nathan Goodyear on 16 Dec 10
     
    Joint statement on early treatment of thyroid disease and subclinical thyroid dysfunction from The american association of clinical endocrinologists, the American Thyroid Association, and the Endocrine Society
Nathan Goodyear

TSH may not be a good marker for adequate thyroid ... [Wien Klin Wochenschr. 2005] - Pu... - 0 views

www.ncbi.nlm.nih.gov/...16416346

TSH thyroid hormone replacement therapy

shared by Nathan Goodyear on 16 Dec 10 - No Cached
  • TSH levels used to monitor substitution, mostly regulated by intracellular T3 in the pituitary, may not be such a good indicator of adequate thyroid hormone action in all tissues
  • Nathan Goodyear on 16 Dec 10
     
    TSH may not be a good marker for adequate thyroid hormone replacement therapy.
Nathan Goodyear

Omega Research - 0 views

www.omega-research.com/researchview.php

omega-3 alzheimer's disease amyloid oxidative stress

shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • Nathan Goodyear on 15 Dec 10
     
    omega-3 limit amyloid and oxidative damage; thus may decrease alzheimer's disease risk
Nathan Goodyear

Environmental Lead Exposure and Progression of Chronic Renal Diseases in Patients witho... - 0 views

www.nejm.org/...NEJMoa021672

EDTA chelation chronic renal insufficiency

shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • Low-level environmental lead exposure may accelerate progressive renal insufficiency in patients without diabetes who have chronic renal disease. Repeated chelation therapy may improve renal function and slow the progression of renal insufficiency
  • Nathan Goodyear on 15 Dec 10
     
    EDTA chelation aids in lead induced chronic renal insufficiency
Nathan Goodyear

The Toxicology of Mercury - Current Exposures and Clinical Manifestations - NEJM - 0 views

www.nejm.org/...NEJMra022471

Mercury toxins toxicology

shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • The Toxicology of Mercury — Current Exposures and Clinical Manifestations
  • Nathan Goodyear on 15 Dec 10
     
    Nice review of the toxicology of Mercury
Nathan Goodyear

Lead-Chelation Therapy -- A Treatment for Chronic Renal Disease? - General Medicine - 1 views

general-medicine.jwatch.org/...1

EDTA chelation renal insufficiency lead

shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • Therapy with EDTA delayed the progression of chronic renal insufficiency in patients with high-normal body lead burdens
  • Nathan Goodyear on 15 Dec 10
     
    Therapy with EDTA delayed the progression of chronic renal insufficiency in patients with high-normal body lead burdens
Nathan Goodyear

Effects of ethyl-eicosapentaenoic acid omega-3 fat... [Menopause. 2009 Mar-Apr] - PubMe... - 0 views

www.ncbi.nlm.nih.gov/...19034052

omega-3 omega EPA hot flashes

shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • Effects of ethyl-eicosapentaenoic acid omega-3 fatty acid supplementation on hot flashes and quality of life among middle-aged women: a double-blind, placebo-controlled, randomized clinical trial.
  • Supplementation with E-EPA omega-3 fatty acid reduced HF frequency and improved the HF score relative to placebo
  • Nathan Goodyear on 15 Dec 10
     
    omega-3 aids in hot flash relief
Nathan Goodyear

Ethyl-eicosapentaenoic acid for the treatment of psychological distress and depressive ... - 0 views

www.ajcn.org/...641.full

Omega-3 depression

shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • he 8-wk changes in PD and depressive scales improved significantly more with E-EPA than with placebo.
  • Nathan Goodyear on 15 Dec 10
     
    omega-3 improves depressive and psychological distress symptoms
Nathan Goodyear

Omega Research - 0 views

www.omega-research.com/researchview.php

Omega-3 vitamin C E antioxidants oxidative stress infertility

shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • These data have important implications for the supplementation of a combination of omega-3 fatty acids and antioxidants in the successful management of female infertility.
  • Nathan Goodyear on 15 Dec 10
     
    omega 3 and antioxidants aid in infertility
Nathan Goodyear

Omega Research - 0 views

www.omega-research.com/researchview.php

omega Omega-3 diabetes

shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • Nathan Goodyear on 15 Dec 10
     
    higher omega-3 intake = lower type 2 diabetes
Nathan Goodyear

Insulin Receptor Expression and Function in Human Breast Cancer Cell Lines - Cancer Res - 0 views

cancerres.aacrjournals.org/...3924.short

insulin breast cancer receptors

shared by Nathan Goodyear on 11 Dec 10 - No Cached
  • This present study indicates therefore that in breast cancer cell lines there are functional insulin receptors that regulate breast cancer cell growth.
  • Nathan Goodyear on 11 Dec 10
     
    breast cancer cells express high functioning insulin receptors
Nathan Goodyear

The syndrome of irreversible lithium-effectuated n... [Clin Neuropharmacol. 2005 Jan-Fe... - 0 views

www.ncbi.nlm.nih.gov/...15714160

Lithium neurotoxicity

shared by Nathan Goodyear on 10 Dec 10 - No Cached
  • Nathan Goodyear on 10 Dec 10
     
    Silent but irreversible lithium-induced neurotoxicity
Nathan Goodyear

Antipsychotic drug use and mortality in older adul... [Ann Intern Med. 2007] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...17548409

anti-psychotics neuroleptics

shared by Nathan Goodyear on 10 Dec 10 - No Cached
  • Atypical antipsychotic use is associated with an increased risk for death compared with nonuse among older adults with dementia
  • Nathan Goodyear on 10 Dec 10
     
    up to 1.55 x increase risk of death with antipsychotic use
Nathan Goodyear

Predicting the long-term risk of tardive dyskinesi... [J Clin Psychiatry. 1993] - PubMe... - 0 views

www.ncbi.nlm.nih.gov/...8098030

Neuroleptics Tardive Dyskinesias

shared by Nathan Goodyear on 10 Dec 10 - No Cached
  • , we estimate the risk of persistent TD to be 32% after 5 years of neuroleptic exposure (95% confidence interval [CI] = 23%-43%), 57% after 15 years of exposure (95% CI = 47%-66%), and 68% after 25 years of exposure
  • Nathan Goodyear on 10 Dec 10
     
    Neuroleptics significantly increase risk of Tardive Dyskinesias: we should think before we prescribe
Nathan Goodyear

Addition of omega-3 fatty acid to maintenance medi... [Am J Psychiatry. 2002] - PubMed ... - 0 views

www.ncbi.nlm.nih.gov/...11870016

Omega-3 depression

shared by Nathan Goodyear on 10 Dec 10 - No Cached
  • Highly significant benefits of the addition of the omega-3 fatty acid compared with placebo were found by week 3 of treatment.
  • Nathan Goodyear on 10 Dec 10
     
    Addition of omega-3 fatty acid to maintenance medication treatment for recurrent unipolar depressive disorder.
Nathan Goodyear

Impaired clearance, not overproduction of toxic proteins, may underlie Alzheimer's dise... - 0 views

www.nih.gov/...ninds-09.htm

alzheimer's disease detoxification

shared by Nathan Goodyear on 09 Dec 10 - No Cached
  • Nathan Goodyear on 09 Dec 10
     
    Impaired clearance, not overproduction of toxic proteins, may underlie Alzheimer's disease
Nathan Goodyear

S-adenosyl-l-methionine (SAMe) as antidepressant: ... [Acta Neurol Scand Suppl. 1994] -... - 0 views

www.ncbi.nlm.nih.gov/...7941964

SAMe depression

shared by Nathan Goodyear on 09 Dec 10 - No Cached
  • The efficacy of SAMe in treating depressive syndromes and disorders is superior with that of placebo and comparable to that of standard tricyclic antidepressants. Since SAMe is a naturally occurring compound with relatively few side-effects, it is a potentially important treatment for depression
  • Nathan Goodyear on 09 Dec 10
     
    S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies.
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