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Nathan Goodyear

American Institute for Cancer Research (AICR): Media Advisory: Cancer Group Finds Exces... - 0 views

  • Cancer Group Finds Excess Body Fat Alone Causes More Than 100,000 Cancers in U.S
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    obesity causes 100,000 cases of Cancer annually
knackglobal

Knack Global is leading provider of revenue cycle management solutions to the health-ca... - 0 views

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    Knack Global is the leading service provider into the U.S. Healthcare sector, we provide services in healthcare IT, enterprise IT and analytics
spineneuro

Best Hospital for VBT Surgery India Offers Solution for Pediatric Scoliosis - 101 Press... - 0 views

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    Best hospital for VBT surgery India uses a new device (known as The Tether™) for VBT approved by the U.S. Food & Drug Administration in August 2019. Spine and Neuro Surgery Hospital India International Helpline Number : +91-9325887033 Email Id: enquiry@spineandneurosurgeryhospitalindia.com
Nathan Goodyear

The 20-Year Public Health Impact and Direct Cost of Testosterone Deficiency in U.S. Men... - 0 views

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    This study assumes a 13% low T prevalence.  Probably too low.  This will only grow.  Low T contributes to many disease states in men. This study showed a cost of 190-525$ billion in cost from these disease states over a 20 year time period.
Nathan Goodyear

In U.S., Obesity Up in Nearly All Age Groups Since 2008 - 0 views

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    Obesity has increased in almost every category from 2008 to present.
Nathan Goodyear

Obesity and Overweight for Professionals: Data and Statistics: U.S. Obesity Trends | DN... - 0 views

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    US obesity Trends.  Just watch short animated map to see the unprecedented problem facing America.
Nathan Goodyear

Too Few Doctors in Many U.S. Communities - NYTimes.com - 0 views

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    Physician shortage predicted to worsen.  Too high a demand; and too little supply.
ind swift

Gynecology Drugs| Pharmaceutical Formulations Development | Indian Drug Manufacturers - 1 views

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    4 ANAPROCT CAP Each Capsule Contains: Neem (Azadirachta Indica) 25 Mg Suran (Amorphophallus Companulatus) 25 Mg Yashtimadhu (Glycirrhiza Glabra) 25 Mg Haritaki (Terminalia Chebula) 25 Mg Kumarighansatva (Aloe Vera) 50 Mg Mukta Shukti Bhasma(Pearl Oyster) 75 Mg Arishtak (Sapindus Trifoliatus) 75 Mg Saphatika Bhasma (Potash Alum) 100 Mg Daruhaldi Ghansatva(Ext.Berberis Aristata)100 Mg Capsule Anit-Haemorroidal Haemostat 5 ANAPROCT OINTMENT Lidocaine U.S.P.
Nathan Goodyear

Prevalence of Diabetes Mellitus in U.S. Youth in 2009: The SEARCH for Diabetes in Youth... - 0 views

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    SEARCH study finds significantly increased rates of type I and type II diabetes in children from 2000 to 2009.
Nathan Goodyear

Association between Lead and Cadmium and Reproductive Hormones in Peripubertal U.S. Girls - 0 views

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    Study finds higher Pb levels in young girls is associated with delayed puberty onset.  This occurs through an inverse relationship with inhibin B and follicular development.  This relationship was also found with Cadmium.  Both of these heavy metals are toxic to the ovaries.
Nathan Goodyear

Environmental Chemicals in Pregnant Women in the U... [Environ Health Perspect. 2011] -... - 0 views

  • Conclusions: Pregnant women in the U.S. are exposed to multiple chemicals
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    Pregnancy and toxins
Nathan Goodyear

Magnesium metabolism in health and disease. [Dis Mon. 1988] - PubMed result - 0 views

  • Less than 1% of the total body magnesium is present in blood
  • A large segment of the U.S. population may have an inadequate intake of magnesium and may have a chronic latent magnesium deficiency that has been linked to atherosclerosis, myocardial infarction, hypertension, cancer, kidney stones, premenstrual syndrome, and psychiatric disorders.
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    Magnesium in health and disease
Nathan Goodyear

Environmental Health Perspectives: Relationship between Urinary Phthalate and Bisphenol... - 0 views

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    Phthalate and Bisphenol A interferes with thyroid levels
Nathan Goodyear

Obese Americans now outweigh the merely overweight | Reuters - 0 views

  • Numbers posted by the National Center for Health Statistics show that more than 34 percent of Americans are obese, compared to 32.7 percent who are overweight. It said just under 6 percent are "extremely" obese.
  • More than one-third of adults, or over 72 million people, were obese in 2005-2006, the NCHS said in its report
  • In May, the CDC reported that 32 percent of U.S. children fit the definition of being overweight, 16 percent were obese and 11 percent were extremely obese.
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    obesity in America
Nathan Goodyear

PLOS ONE: Persistent Organic Pollutants and Early Menopause in U.S. Women - 0 views

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    study identifies 15 Endocrine Disrupting Chemicals that lead to earlier Menopause.  Maybe we should change it to Chemopause.
Nathan Goodyear

Evidence of estrogenic endocrine disruption in smallmouth and largemouth bass inhabitin... - 0 views

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    Is our effect on the environment and the environments, in turn, effect on us politics or science?  It is science that is manipulated by politicians for political gain/power.  In this study of male small/large mouth bass in NE America are found to have significant female characteristics  i.e. eggs where testes should exist...where none should exist.  The numbers were as high as 85% in the small mouth base compared to 27% for the large mouth bass.  Is there any wonder we have a low T epidemic in men?  The most likely cause are endocrine disruptors.  It is a concern that the authors did not look for endocrine disruptors in the water at the time of this study of the fish.
Nathan Goodyear

Physical activity and telomere length in U.S. men and women: An NHANES investigation - 0 views

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    longer Telomere lengths in those with regular exercise beyond the age of 40.
healthinfomag

Why New Zealand and Vietnam are more successful against COVID-19 than the United States... - 0 views

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    Every country is trying to combat with COVID-19 according to its resources. Politicians, doctors, scientists and economy experts are trying to find a perfect mix which can work well in this situation. Some countries are acting smartly. Along with these efforts, they are also observing the conditions of other countries to improvise their policies.
Nathan Goodyear

The Role of Vitamin C in Human Immunity and Its Treatment Potential Against COVID-19: A... - 0 views

  • vitamins A, B, C, E, B6, B12, folate, zinc, iron, copper, and selenium
  • White blood cells, including neutrophils and monocytes, accumulate concentrations of vitamin C up to 100 times greater than that of plasma
  • Vitamin C is a crucial component of both the innate (nonspecific) and adaptive (specific) portions of the immune system
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  • play a role during the initial chemotactic response of neutrophils shortly after infection
  • following vitamin C supplementation, a 20% increase in neutrophil chemotactic activity was observed
  • also contributes to the phagocytosis and killing of microbes by neutrophils
  • low levels of vitamin C occurring in high-stress situations
  • maturation, proliferation, and viability of T cells have all been shown to be upregulated by the presence of normal physiologic concentrations of vitamin C
  • Vitamin C has been shown to directly affect the number of Igs released from B cells
  • vitamin C among healthy young adult males showed a significant increase in serum levels of IgA, IgG, and IgM
  • effects of high-dose vitamin C on cytokine levels in cancer patients, finding decreased amounts of the cytokines Interleukin-1 alpha (IL-1 alpha), IL-2, IL-8, and tumor necrosis factor-alpha (TNF-alpha) after high-dose vitamin C infusion
  • when vitamin C was supplemented with vitamin E in healthy adults, it increased the production of cytokines IL-1 beta and TNF-alpha
  • vitamin C acts to modulate the levels of cytokines to prevent them from fluctuating in either direction
  • vitamin C also acts as an important antioxidant to the cells of the immune system.
  • human leukocytes, neutrophils, in particular, possess the ability to transport the oxidized form of vitamin C across its membrane to use as a defense mechanism against ROS produced during an immune response
  • Vitamin C also can recover other endogenous antioxidants in the body such as vitamin E and glutathione, returning them to their active state
  • vitamin C can decrease the activation of NF-kB
  • can reduce harmful nitrogen-based compounds such as N-nitrosamines and nitrosamides, both of which are carcinogenic 
  • subjects taking oral vitamin C supplementation saw a 60% to 90% reduction in oxidative stress compared to a placebo control
  • subjects infused with vitamin C alone had a 516% increase in glutathione levels compared to subjects not provided the 500 mg daily supplementation
  • hydroxylating proline and lysine
  • mature and stabilize the tissue of a healing wound
  • healing
  • oral surgery
  • improved soft tissue regeneration
  • vitamin C increases the mRNA levels of type I and type III collagen in the human dermis
  • Studies have demonstrated that those with low levels of vitamin C are at a significantly higher risk of respiratory infection compared to those with normal levels
  • viral cold duration was reduced by about 8% in adults and 13.5% in children using prophylactic daily doses of 200 mg of oral vitamin C
  • prophylactically supplementing vitamin C decreases the risk of infection with respiratory viruses such as the common cold
  • combined with probiotics, oral vitamin C supplementation showed a 33% decrease in the incidence of respiratory tract infections in preschool-age children [
  • high-dose oral supplementation of vitamin C managed to prevent or reduce symptoms if taken before or just after the onset of cold- or flu-like symptoms
  • improvements in oxygen saturation and decreased IL-6 levels (a marker of inflammation) in the treatment group compared to the control group
  • 8 g doses of oral vitamin C
  • there is a negative correlation between age and serum levels of vitamin C
  • Patients with COVID-19 will likely also experience depletion in serum levels of vitamin C as a direct result of the upregulation of the immune system to combat the infection
  • Colunga et al. suggested that oral vitamin C can be combined with oral Quercetin, an antiviral flavonoid, to improve Quercetin’s ability to block viral membrane fusion of SARS-CoV-2
  • high doses of 1-2 g/day of oral vitamin C could prevent other upper respiratory infections
  • It appears vitamin C supplementation by itself does not provide a striking benefit in preventing COVID-19 infection for those without a deficiency
    • Nathan Goodyear
       
      Flawed statement. What is normal? Vitamin D. Many variables effect levels and dose, including the two compartment kinetics and absorption.
  • Hiedra et al. were able to show decreases in inflammatory biomarkers, such as D-dimer and ferritin
  • some evidence to support that prophylactic use of vitamin C helps reduce the severity of respiratory infection symptoms once a subject has already been infected
  • oral vitamin C in combination with zinc provided the largest amount of antibody titers 42 days
  • linear relationship between days of vitamin C therapy and survival duration
  • other studies were unable to find any definitive improvement concerning therapy with vitamin C
    • Nathan Goodyear
       
      Either these studies are designed to fail or the authors are lacking some basic understanding of pharmacokinetics and pharmacodynamics with vitamin C.
  • Fowler et al. aimed to see if a high-dose vitamin C infusion would benefit patients affected by ARDS, but they were unable to conclude that vitamin C infusion, compared to a placebo, could decrease vascular inflammation and damage in ARDS
    • Nathan Goodyear
       
      At what dose, duration, frequency???
  • in a sample of 67 COVID-19-positive ICU patients, 82% of them displayed plasma vitamin C levels below 0.4 mg/dL
    • Nathan Goodyear
       
      They are kind of make the point from my earlier note.
  • continuous vitamin C infusion at a rate of 60 mg/kg/day for four days decreased the need for mechanical ventilation and vasopressor use but had no significant effect on overall mortality
    • Nathan Goodyear
       
      Again, designed to fail or ignorance designed the study which failed
  • Carr et al. suggested that high-dose IV vitamin C is most effective when treating sepsis as septic patients receiving the normal daily recommendations through diet still showed decreased vitamin C levels
  • High-dose IV vitamin C treatment has also been shown by Kakodkar et al. to decrease syndecan-1, an endothelial glycocalyx that contributes to mortality in septic patients
  • combined with hydrocortisone and thiamine, septic patients treated with 1.5 g of IV vitamin C every six hours showed a distinct decrease in their SOFA scores and none of the patients treated developed organ failure
  • combined with hydrocortisone and thiamine, septic patients treated with 1.5 g of IV vitamin C every six hours showed a distinct decrease in their SOFA scores and none of the patients treated developed organ failure
  • reduced overall mortality
  • reduced overall mortality
  • propose the use for high-dose vitamin C to aid in the treatment of septic shock-induced hypotension
  • treatment of severe sepsis using a high dose (up to 200 mg/kg/day) of IV vitamin C was explored in phase I, a double-blind, randomized, placebo-controlled trial by Fowler et al. [75]. Their findings included a reduction in SOFA scores and decreased vascular injury compared to a placebo control group, all while showing minimal adverse side effects
    • Nathan Goodyear
       
      High dose here is laughable. Again, duration and frequency also.
  • Maintaining a daily intake of 75 and 100 mg for men and women, respectively, as recommended by the U.S. Institute of Medicine
    • Nathan Goodyear
       
      This recommendation is FRANK IGNORANCE
Nathan Goodyear

The Veterans ECS21 (Exploring Cannabigerol for Sleep) Study: A protocol for the first r... - 0 views

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    Safe @ doses of CBG 25-50 mg in veterans.
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