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pharmacybiz

Lateral Flow Tests Shortages Bear Customers Wrath - 0 views

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    Increased demand and shortages of lateral flow tests are pushing staff at pharmacies to bear the brunt from frustrated customers who are unable to get their free lateral flow tests, Daily Mail reported. Some Britons claimed that they have been unable to get lateral flow tests at their local pharmacies for up to a fortnight while some pharmacies were forced to put up sign warning stating they have run out of free tests. Given the patchy supply of test kits, pharmacy bosses warned that staff are facing 'unfair' and 'abusive' behaviour by customers, the newspaper reported.Dr Leyla Hannbeck, chief executive of the Association of Independent Multiple Pharmacies (AIMP), told the newspaper: "Up until yesterday the supply to pharmacies was still patchy. The past few days the situation has not improved. "Pharmacies are having to put up with a lot of abuse and aggressive behaviours by members of the public because of this situation which is unfair. "The demand is still very high now because the governments guidelines put a lot of emphasis on testing as a key out of self isolation, so naturally as Omicron cases are high people are reliant on tests to get on with daily life."
olivehealthcare

DNA Testing - Olive Health & Travel Clinic, Ilford, London - 0 views

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    In legal cases, DNA Testing performed by only registered nurses, doctors or accredited individuals. At Olive Health & Travel Clinic We offer pregnancy tests by a choice of blood test and urine test. Blood tests are more sensitive than urine tests so we prefer urine test for assurance.
pharmacybiz

Avacta Halts Sale Of Covid-19 Rapid Antigen LFT - 0 views

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    Britain's biotech firm Avacta Group on Monday (January 10) announced halting sales of its Covid-19 rapid antigen lateral flow test AffiDX to replace antibodies in the device and increase its ability to diagnose the Omicron variant. The company stated that AffiDX is capable of detecting Omicron when the virus is present in high numbers in samples, but the sensitivity of the test reduces at lower viral loads. The performance of all rapid antigen tests came under scanner in wake of a large number of mutations in the Omicron variant. AffiDX contains both a proprietary Affimer reagent and a commercially available antibody. The Affimer reagent detects the Omicron variant with the same sensitivity as the Delta variant, and performance of the antibody is paired with the Affimer reagent in the test. This has been affected by the additional Omicron mutations, the firm said. Alastair Smith, chief executive of Avacta Group, said: "Our determination to only provide high quality, high performance diagnostic tests has led us to the correct decision to pause all marketing of the AffiDX® lateral flow antigen test. We have, of course, been unable to market the product in the UK since October 2021, as the product continues to await approval under the new CTDA regulatory process.
pharmacybiz

10.5 M LFD Test Kits : UKSHA Plans To Distribute It Per Week - 0 views

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    As an unprecedented demand for Lateral Flow Device (LFD) test kits continues through the Pharmacy Collect service, the UK Health Security Agency (UKHSA) is planning to distribute 10.5 million tests per week via Alliance Healthcare this month. By the end of this week (January 8), the UKHSA aims to distribute more than 8 million tests to Alliance Healthcare - sole distributor to pharmacies. The announcement comes after many in the pharmacy sector voiced concerns over shortage of test kits. Earlier this week, it emerged that Alliance Healthcare closed for four days shortly after receiving around 2.5 million tests on Christmas Eve. Meanwhile, the UKHSA indicated that Alliance Healthcare has been delivering 86 per cent of its orders within 24 hours of the pharmacy order, nearly half of that on the same day. Besides, a plan to switch on a Parcel Force delivery contingency is being finalised by UKHSA, which would enable supply of a further 3.5 million test kits.
olivehealthcare

Pregnancy Tests - Olive Health & Travel Clinic in Ilford, London - 0 views

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    We offer pregnancy tests at our Clinic by a choice of blood test and urine test. All pregnancy tests measure the amount of human chorionic gonadotrophin (hCG), the pregnancy hormone, in your body.
olivehealthcare

Blood Tests | Blood Test at Home | Mobile Phlebotomy - 0 views

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    We offers the full range of blood tests with results available as early as 48 hours. Home-visits (mobile phlebotomy) offered for blood sample collection for both NHS and Private blood tests. Pregnancy HCG, Hepatitis B Immunity, Tuberculosis, Occupational Health, Vitamin tests, Glucose, Cholesterol, etc.
olivehealthcare

Olive Health & London Travel Clinic | Blood Tests | Private BCG London - 0 views

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    Olive health & travel clinic ilford, London provide quality medical services in different fields like Private BCG london, Slimming jab, InterVax, Mobile phlebotomy, BCG NHS, Umrah vaccination, Ear irrigation, Hajj vaccination, BCG Injection. We also provide Travel vaccinations and antimalarials, Health Immunisations such as BCG, Shingles, HPV, Meningitis, Hepatitis B etc., Blood tests, Mobile phlebotomy (blood tests at home), Ear wax removal by irrigation method, Weight loss clinic (Saxenda), DNA/Paternity tests, and a range of health checks including STI testing.
Nathan Goodyear

PLOS ONE: Probiotic Microbes Sustain Youthful Serum Testosterone Levels and Testicular ... - 0 views

  • Studies in both humans and rodents, however, suggest that low testosterone is due to age-related lesions in testes rather than irregular luteinizing hormone metabolism
  • Various dietary factors and diet-induced obesity have been shown to increase the risk for late onset male hypogonadism and low testosterone production in both humans and mice
  • Testosterone deficiency and metabolic diseases such as obesity appear to inter-digitate in complex cause-and-effect relationships
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  • dietary supplementation of aged mice with the probiotic bacterium Lactobacillus reuteri makes them appear to be younger than their matched untreated sibling mice
  • These results indicate that gut microbiota induce modulation of local gastrointestinal immunity resulting in systemic effects on the immune system which activate metabolic pathways that restore tissue homeostasis and overall health
  • all these studies we consistently observed that young and aged mice consuming purified L. reuteri organisms had particularly large testes and a dominant male behavior.
  • The testes of probiotic-fed aged mice were rescued from both seminiferous tubule atrophy and interstitial Leydig cell area reduction typical of the normal aging process. Preservation of testicular architecture despite advanced age or high-fat diet coincided with remarkably high levels of circulating testosterone. The beneficial effects of probiotic consumption were recapitulated by the depletion of the pro-inflammatory cytokine Il-17.
  • feeding of L. reuteri consistently increased the gonadal weights, consumption of a non-pathogenic strain of Escherichia coli (E. coli) K12 organisms did not affect testicular weight
  • mice with dietary L. reuteri supplements were rescued from diet-induced obesity and had normal body weight and lean physique
  • Despite the comparable numbers of ST profiles, we determined that testes from L. reuteri-treated mice had increased ST cross-sectioned profiles
  • the probiotic organism induced prominent Leydig cell accumulations in the interstitial tissue between the ST's
  • The probiotic-associated increase of interstitial Leydig cell areas was sustained with advancing age at 7 (CD vs CD+LR, P = 0.0025; CD+E.coli vs CD+LR, P = 0.0251) and 12 months
  • mice eating L. reuteri had profoundly increased levels of circulating testosterone regardless of the type of diet they consumed
  • blocking pro-inflammatory Il-17 signaling entirely recapitulates the beneficial effects of probiotics
  • previous studies we found that dietary probiotics counteract obesity [19] and age-related integumentary pathology [18] at least in part by down-regulating systemic pro-inflammatory IL-17A-dependent signaling
  • Testes histomorphometry and serum androgen concentration data were both suggestive of a probiotic-associated up-regulation of spermatogenesis in mice
  • Lactobacillus reuteri we discovered that aging male animals had larger testes compared to their age-matched controls
  • xamined testes of probiotic microbe-fed mice and found that they had less testicular atrophy coinciding with higher levels of circulating testosterone compared to their age-matched controls
  • Similar testicular health benefits were produced using systemic depletion of the pro-inflammatory cytokine Il-17 alone, implicating a chronic inflammatory pathway in hypogonadism
  • One specific aspect of this paradigm is reciprocal activities of pro-inflammatory Th-17 and anti-inflammatory Treg cells
  • Feeding of L. reuteri organisms was previously shown to up-regulate IL-10 levels and reduce levels of IL-17 [19] serving to lower systemic inflammation
  • insufficient levels of IL-10 may increase the risk for autoimmunity, obesity, and other inflammatory disease syndromes
  • Westernized diets are also low in vitamin D, a nutrient that when present normally works together with IL-10 to protect against inflammatory disorders
  • Physiological feedback loops apparently exist between microbes, host hormones, and immunity
  • The hormone testosterone has been shown to act directly through androgen receptors on CD4+ cells to increase IL-10 expression
  • studies in both humans and rodents suggest that hypogonadism is due to age-related lesions in testes rather than irregular LH metabolism
  • We postulate that probiotic gut microbes function symbiotically with their mammalian hosts to impart immune homeostasis to maintain systemic and testicular health [34]–[35] despite suboptimal dietary conditions.
  • Dietary factors and diet-induced obesity were previously shown to increase risk for age-associated male hypogonadism, reduced spermatogenesis, and low testosterone production in both humans and mice [2]–[4], [8]–[11], [14]–[17], phenotypic features that in this study were inhibited by oral probiotic therapy absent milk sugars, extra protein, or vitamin D supplied in yogurt.
  • Similar beneficial effects of probiotic microbes on testosterone levels and sperm indices were reported in male mice that had been simultaneously supplemented with selenium
  • L. reuteri-associated prevention of age- and diet-related testicular atrophy correlates with increased numbers and size of Leydig cells
  • the initial changes of testicular atrophy begin to occur in mice from the age of 6 moths onwards [7] and indicates that the trophic effect of L. reuteri on Leydig cells is a key event which precedes and prevents age-related changes in the testes of mice. This effect is reminiscent of earlier studies describing Leydig cell hyperplasia and/or hypertrophy in the mouse and the rat testis that were achievable by the administration of gonadotropins, including human chorionic gonadotropin, FSH and LH
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    Fascinating study on how the addition of Lactobacillus reuteri increased Testicular size, prevented testicular atrophy, increased serum Testosterone production and protected against diet-induced/obesity-induced hypogonadism.  This was a mouse model
Nathan Goodyear

Salivary cortisol determined by enzyme immunoassay is preferable to serum total cortiso... - 0 views

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    salivary testing of cortisol proven to be a better test than blood cortisol.  Published in Clinical Endocrinology, '05.  Salivary cortisol testing is best test to evaluate cortisol levels.
topshealthy

Best Homemade Pregnancy Test - Topshealthy.com - 0 views

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    Many people are probably wondering what is homemade pregnancy test. Pregnancy is normal for women. Giving birth has been done for a couple of thousands of years. There are a couple of options of going to doctor or purchasing pregnancy test from pharmacy that were not available to the modern women ancestors. They used homemade pregnancy test and you can still use their traditional methods nowadays.
Nathan Goodyear

Sensitivity and specificity of six tests for the diagnosis of adult... - PubMed - NCBI - 0 views

  • ARG plus GHRH test, high sensitivity (96 and 95%, respectively) and specificity (92 and 91%, respectively) for GH deficiency were achieved
  • The greatest diagnostic accuracy occurred with the ITT and the ARG plus GHRH test
  • 95% specificity could be achieved with the ARG plus L-DOPA and ARG tests only with very low peak GH cut-points (0.25 and 0.21 microg/liter, respectively) and not at all with the L-DOPA test
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  • Although serum IGF-I levels provided less diagnostic discrimination than all five GH stimulation tests, a value below 77.2 microg/liter was 95% specific for GH deficiency
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    study evaluated 6 tests for HGH deficiency diagnosis.  Ninety-five percent specificity found with ARG + l-DOPA and ARG alone.  However, the authors found a 95% specificity with IGF-1 < 77.  Although, IGF-1 is false negative in up to 65% of those with HGH deficiency.
Nathan Goodyear

False-positive results released by direct-to-consumer genetic tests highlight the impor... - 0 views

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    Consumers beware: direct to consumer genetic testing found to have 40% false positive rates with misclassification of variants. This also includes the interpretative reports that often accompany the direct to consumer genetic test companies or included from 3rd parties. This could have huge implications in the use of Epigenetics, pharmacogenetics, and Cancer genetics.  These genetic testing needs medical interpretation not algorithms.
vishal Parasrampuria

How to Perform Testing of Glass and PET bottles? - 0 views

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    Some of the testing procedures are as same as Pet bottle testing. However, glass bottles don't undergo bursting tests etc. If the quality manager wants to do the same, there are specially designed machines with closed cavities, to avoid any mishap when bottle bursts.
Nathan Goodyear

Steroid Analysis in Saliva: An overview - 0 views

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    No test is perfect. This study analyzes problems with saliva hormone testing.  The authors of this study found saliva testing optimal for cortisol and less so for sex hormones.  Other studies have contradicted this conclusion.
Nathan Goodyear

Salivary Sex Hormone Measurement in a National, Population-Based Study of Older Adults - 0 views

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    Another study supports saliva hormone testing.  This study involved 2,722 individuals and tested estradiol, progesterone, DHEA and testosterone in men and women.  All of these are sex hormones.  Someone needs to tell the insurance companies that the overwhelming evidence supports saliva hormone testing.  But, that would mean they are even interested in the science.
Sundhar krishna

Vision Test Chennai - 0 views

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    Krishna Eye and Ent Hospital specialised in vision test. We offer refractive surgery and vision test for myopia, short sight, long site, hypermetropia, shortsightedness and farsightedness.
Nathan Goodyear

ScienceDirect - Fertility and Sterility : At home testing: optimizing management for th... - 0 views

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    At home testing, via saliva testing will benefit couples with infertility
Nathan Goodyear

Current Status of Salivary Hormone Analysis -- Gröschl 54 (11): 1759 -- Clini... - 0 views

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    saliva testing of hormones said to be "reliable and, in some cases, even superior to other body fluids".  Of course, no test is perfect, but saliva test provides that best assessment available
Nathan Goodyear

Salivary Cortisol Can Replace Free Serum Cortisol Measurements in Patients With Septic ... - 0 views

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    salivary cortisol testing is shown to be good alternative to serum cortisol testing.  "very good correlation", "noninvasive", "easy to perform" are just some of the descriptions of salivary cortisol testing in this study
Nathan Goodyear

Role of salivary cortisol determinations in the diagnosis of... : Current Opinion in En... - 0 views

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    salivary cortisol testing said to be "screening test of choice".  Salivary cortisol testing validated.
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