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This study is misleading.  Their conclusion is that D2 and D3 are equivalent in raising 25-OH vitamin D via po form preferentially over the IM form. However, when you look at the results, the response of D3 was statistically significant over that of D2.  That is the conclusion: vitamin D3 is the optimal form of vitamin D.

lower Selenium levels found in those with autism, though not statistically significant.

Study finds that curcumin alone is better than Prozac for Major depression.  Though not statistically significant, the response rate as determined by the Hamilton Depression scale favored curcumin above that of Prozac.  The effective dose was 1000 mg in this study.  The combination also provided additional benefit above that of prozac alone.

Testosterone levels associated with hemoglobin in men.  This association was statistically significant.  The association was less in women.  This study looked at hemodialysis patients only.

startling statistics on the damage done by prescribed medicine and medical therapies.

Truly horrifying statistic not reported anywhere.  Hospital care has been associated with > 400,000 deaths annually.  The third leading cause of death is medical therapies/treatments.

Study finds that low Testosterone preoperative is associated with increased positive surgical margins and worse staging post radical prostatectomy.  Also association with a non-statistical increase in biochemical failure.

No significant statistical significance was found with vitamin D therapy and insulin sensitivity.  However, improved outcomes were found in 2 hour insulin and 2 hour glucose levels after a 75 gram OGTT.

Startling statistic--25% of men started on Testosterone therapy have had not diagnostic evaluation of Testosterone levels.

Some startling statistics in this 2013 review on Testosterone in men.  Studies reflect an inverse relationship between Testosterone and CAD severity.  That is, the lower the Testosterone levels, the increase in severity of CAD. This same association was also found with CHF.  Low Testosterone is common in those with CAD, CHF, type II diabetes, increased IMT in carotids and aorta, and obesity when compared to "healthy" individuals.  Testosterone therapy in those with CAD found benefits: prolongation of ST segment depression, coronary vasodilation, improved exercise capacity in those with CHF, shift to type I muscle fibers, shorten the QTc interval.  Testosterone therapy has been shown to improve insulin resistance, improve HgbA1c and decrease waist circumference and fat loss in obese individuals.  Otherwise, a good review of the association between a declining Testosterone and cardiovascular disease.

no statistical significant association between 2OH-estrone, 16-alpha-OH-estrone, and their ratio found to be associated with increased breast cancer risk in pre menopause women.

Good review of the data from the WHI-HT on estrogen metabolites and breast cancer risk.  Increased 2-OHestrone and 2:16 ratio without statistical significance reached.

Study results suggest that higher Testosterone and lower Estrogen levels provide anti-inflammatory effects in men.  The inflammatory biomarker assessed here was CRP.  Low total and calculated free Testosterone was associated with an increase in CRP.  In contrast, total and free Estrogen was associated with an increase in CRP.  Estradiol increased WBC count and SHBG was inversely related to WBC count in this study.

Low total Testosterone, low free Testosterone, and low SHBG associated with increased CRP.  Serum total estradiol and free estradiol trended to a positive association, but did not reach statistical significance.

40 week study finds that low Testosterone is associated with increased 10 risk of cardiac adverse events.  This was also associated with elevated BNP and hs-cardiac Troponin.  The study found that Testosterone therapy did decrease BNP, though not statistically significant; no effect on hs-cardiac troponin was found.

topical nicotinamide statistically improves acne in 8 week trial.  Nicotinamide actually out performed clindamycin in this head to head study.

4% niacinamide gel statistically reduces mild/moderate acne in small study.

topical 4% niacinamide gel cream found to statistically reduce mild/moderate acne in young women in small study.

Treatment in subclinical hypothyroidism provides statistical benefits to patient symptoms

exhaustive discussion selenium deficiency and increased cancer risk