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Vitiligo Information - Treat Vitiligo / Leucoderma / White patches with Homeopathy Dr. ... - 0 views

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shared by SEO Husain on 22 Aug 12 - No Cached
  • SEO Husain on 22 Aug 12
     
    Vitiligo (Leucoderma / White patches) is a condition in which skin loses the pigment melanin that determines its color. Treat Vitiligo / Leucoderma / White patches with Homeopathy Dr. Batra's
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Testosterone substitution with a new transdermal, hydroalcoholic gel applied to scrotal... - 0 views

www.eje.org/...317.full testosterone gel andropause men androgens androgen
shared by Nathan Goodyear on 17 May 12 - No Cached
  • Nathan Goodyear on 17 May 12
     
    testosterone gel as effect, and better tolerated, than patch in androgen replacement in men.
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Diabetes Care - 0 views

care.diabetesjournals.org/...dc16-1534 diabetes contraception thromboembolism blood clothes
shared by Nathan Goodyear on 13 Mar 17 - No Cached
  • Nathan Goodyear on 13 Mar 17
     
    contraceptive patch and progestin injectable contraception associated with highest risk of thromboembolism in women with diabetes.

dynamicmedstore - 0 views

started by timjoush1 on 18 Oct 20 no follow-up yet
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Transdermal testosterone replacement therapy in men - 0 views

www.ncbi.nlm.nih.gov/...PMC3891651 Testosterone replacement transdermal low T male hormone hormones
shared by Nathan Goodyear on 05 Feb 14 - No Cached
  • a recent study has suggested that it may sometimes be inaccurate because of abnormal fluctuation of other circulating androgens
    • Nathan Goodyear
      Nathan Goodyear on 05 Feb 14
       
      The authors are referencing the increase in the suggestions to use other testing techniques i.e. saliva.
  • Testosterone therapy can inhibit hepcidin transcription and is associated with increased iron incorporation into red blood cells and increased erythropoietin concentrations
  • Transdermal TRT has a more favorable adverse effect profile when compared to buccal testosterone formulations
  • ...13 more annotations...
  • testosterone concentrations should be checked 2–3 months after initiation of therapy and after adjusting the dose
  • the recommendation for injectable testosterone esters is to check the serum concentration midway between injections
  • it is recommended for serum testosterone to be evaluated 3 to 12 hours after application of the transdermal patch
  • Approximately 0.3% of testosterone is converted into estradiol by aromatase (CYP19A1)
  • a study from 1989 utilizing testosterone transdermally containing 5, 10, or 15 mg of testosterone showed that peak concentrations of testosterone were achieved 3 to 8 hours after scrotal application in hypogonadal men
  • measure serum testosterone any time after the patient has been on treatment with gel for at least 1 week
  • evaluate serum testosterone at the end of the dosing interval for testosterone pellets
  • increased amount of fat leads to increased extragonadal aromatase activity, resulting in increased concentrations of estradiol. High circulating concentrations of estradiol down regulate the HPG axis and decrease the amount of circulating testosterone
  • Up to 80% of plasma estradiol originates from aromatization of testosterone and less than 20% of estradiol in the circulation is secreted by the testes
  • A PSA concentration, digital rectal examination, and hematocrit should be performed at baseline and at 3 months, 6 months, then yearly after TRT is initiated.
  • It is used for many medications and has the advantage of high bioavailability, absence of hepatic first pass metabolism, increased therapeutic efficacy, and steadiness of plasma concentrations of the drug
  • If the hematocrit rises above 54%, treatment should be discontinued
  • elderly men having higher estradiol serum concentrations than postmenopausal women
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Patches of Disorganization in the Neocortex of Children with Autism - NEJM - 0 views

www.nejm.org/...NEJMoa1307491 children autism brain
shared by Nathan Goodyear on 01 Apr 14 - No Cached
  • Nathan Goodyear on 01 Apr 14
     
    New study suggests that intra-uterine exposure effects prefrontal cortex development that leads to autism.  This study was conducted of postmortem samples of children with autism ranging from 2 to 15. Intra-pregnancy exposure of what?  That is the question.  Environmental toxins: whether it is all the xenoestrogens (autism at rate of 5:1 in boys), PCBs, heavy metals, and yes (lead author) preservatives, metals (Al and thermeresol) in vaccines--particularly the flu vaccine which ACOG is almost mandating during pregnancy.

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