metabolic endotoxemia starts with what you eat. Chronic over nutrition results in elevated LPS. This starts a cascade of events that results in inflammation. A well balanced gut flora of bifidobacterium is one way to slow this trigger.
Waist circumference and triglycerides correlate with serum uric acid levels. Men in this study had higher hyperuricemic rates compared to women. Elevated uric acid levels were associated with increased MetS in both sexes and higher normal uric acid levels were also associated with a higher risk of MetS.