Skip to main content

Home/ Dr. Goodyear/ Group items tagged how

Rss Feed Group items tagged

Pursuit Of Healthy Living

Iridology - Study of the Eyes / Iris Health - Medium - 1 views

  •  
    Find out everything you need to know about Iridology like - what it is, how it is helpful in Holistic Health services, what is Iridology Chart, and most importantly mentioning TOP 10 Health Issues that can be detected by Iridology. Credits: Reflectiens.com (Natural Health Services in Ladysmith)
Nathan Goodyear

Acidic extracellular microenvironment and cancer - 0 views

  •  
    Cancer thrives in an acidic micro environment, which also limits penetration of the immune system and other therapies often used in the treatment of cancer.
Nathan Goodyear

How I treat Langerhans cell histiocytosis | Blood Journal - 0 views

  •  
    Langerhans cell histiocytosis
fnfdoc

How Bad Vitamin B12 Deficiency | Your Health Our Priority - 0 views

  •  
    Vitamin b12 called cobalamine, important for vital functions in body, like maintenance. Deficiency cause malnutrition and digestion problems. Treatments including supplements, injections and vitamins regulatory measures.
fnfdoc

How Brain Tumor Affect On Health | Your Health Our Priority - 0 views

  •  
    A brain is an organ often composed of Connective tissues and nerve cells. The brain contains three important parts including breathe controlling and muscles like moving muscles and sensing like emotions breathing, memory thinking and somewhat personality.
fnfdoc

Exactly How Bad Are Trans Fats | Your Health Our Priority - 0 views

  •  
    Are you worried you are getting heavier day by day? Well, it might be because of those fries you are addicted to. Deep fried foods are rich in trans fats which are directly related to obesity and heart failure. Trans fats build up the blood vessels, hindering the smooth flow of blood through them.
Nathan Goodyear

How Food Intakes Modify Testosterone Level - The Journal of Sexual Medicine - 0 views

  •  
    What you eat effects Testosterone levels.
curetick

Walnut Benefits and Side Effects | How to Eat Walnuts - 0 views

  •  
    The walnut benefits can also be useful for weight loss purpose. The containing omega-3 inside the walnut have fatty acids with other substances into it. The 2.5 grams of 'ALA' per serving is found rich beneficial sources as the fatty acid. From studies among the women's observed that having a walnut at diet can be helpful for reducing the weight loss with greater efficiency. It also lowers the 'bad' levels of LDL cholesterol from the body. And the higher levels of 'HDL' cholesterol in a good manner as suggested by the doctors.
herbnclay

Do You Know How Easy It Is To Transform Your Skin Using Clay? - 0 views

  •  
    Clay has always been known for its versatility since ancient times, but right now, it is rage. Clay, especially Calcium Bentonite Clay has medical, therapeutic as well as cosmetic uses. Clay is very beneficial for detoxifying the body inside-out, as it also helps in aiding digestive problems.
fnfdoc

How To Brush Your Teeth Properly | Your Health Our Priority - 0 views

  •  
    We have been using toothbrushes for years and years now. Dentists still think that we are doing it wrong. In this article, we discuss the correct way to clean our teeth. We pave the road to brighter teeth and broader smiles.
fnfdoc

How Lupus Affects The Health? - 0 views

  •  
    SLE or Lupus is an autoimmune disease that causes inflammation of the organs and swelling of the joints. It has vast effects on the renal, skeletal, gastrointestinal and blood systems. It affects mostly people of Chinese and African origin and presents in a capricious and unpredictable manner.
  •  
    10 May Is Lupus Day We Must Know About Lupus
lion2020

Lose weight faster and easier than ever before - 0 views

Burning fat daily is possible with an increased metabolism! Become a Slimmer, More Sexy You! The best way to lose weight I lost 30 pounds in 30 days - 13 weight loss tips - Lose Weight FAST! The Be...

weight lose loss quick programs losing diet plans program weightloss fast fat plan products how to dieting rapid management control tips

started by lion2020 on 13 May 18 no follow-up yet
trungtamnamkhoa

Learn The Pathology Of Premature Ejaculation In Young People - Men's Health Viet Nam - 1 views

  •  
    This situation of "not going to the market has run out of money" is also a complaint that most doctors in Nam Khoa listen to from patients. If from the beginning, sexual and sexual attractions were simply a kind of human instinct, through which the race would be passed on to the next generation, today with development. The prosperity of human society, sex is also a joy, a happiness and sometimes also a powerful demonstration of love for couples. Because of that, the strategy of "beating fast and fast" which is an advantage in the past has become a difficult obstacle for the heart of the foolish love. Let's find out how to overcome "the market has not run out of money" by the article Premature ejaculation cause and treatment - Men Health!
Nathan Goodyear

Tumour-Associated Macrophages (TAMs) in Colon Cancer and How to Reeducate Them - 0 views

  •  
    Great review of TAMs and the benefit to the TME.
Nathan Goodyear

How imiquimod licenses plasmacytoid dendritic cells to kill tumors - 0 views

  •  
    To be read
damienmatcham

How to ensure a healthy heart and body? - 0 views

  •  
    Former Katungul CEO Damien Matcham agrees to the fact that this would bring stiffness to the whole body parts and lower the blood circulation levels inside the body.
Nathan Goodyear

How is the Immune System Suppressed by Cancer - 1 views

  • nitric oxide (NO) released by tumor cells
  • Excellent work by Prof de Groot of Essen, indicated by adding exogenous xanthine oxidase ( XO) in hepatoma cells, hydrogen peroxide was produced to destroy the hepatoma cells
  • NO from eNOS in cancer cells can travel through membranes and over long distances in the body
  • ...43 more annotations...
  • NO also is co linked to VEGF which in turn increases the antiapoptotic gene bcl-2
  • The other important influence of NO is in its inhibition of the proapoptoic caspases cascade. This in turn protects the cells from intracellular preprogrammed death.
  • nitric oxide in immune suppression in relation to oxygen radicals is its inhibitory effect on the binding of leukocytes (PMN) at the endothelial surface
  • Inhibition of inducible Nitric Oxide Synthase (iNOS)
  • NO from the tumor cells actually suppresses the iNOS, and in addition it reduces oxygen radicals to stop the formation of peroxynitrite in these cells. But NO is not the only inhibitor of iNOS in cancer.
  • Spermine and spermidine, from the rate limiting enzyme for DNA synthases, ODC, also inhibit iNOS
  • tolerance in the immune system that decreases the immune response to antigens on the tumors
  • Freund’s adjuvant
  • increase in kinases in these cells which phosphorylate serine, and tyrosine
  • responsible for activation of many growth factors and enzymes
  • phosphorylated amino acids suppress iNOS activity
  • Hexokinase II
  • Prostaglandin E2, released from tumor cells is also an inhibitor of iNOS, as well as suppressing the immune system
  • Th-1 subset of T-cells. These cells are responsible for anti-viral and anti-cancer activities, via their cytokine production including Interleukin-2, (IL-2), and Interleukin-12 which stimulates T-killer cell replication and further activation and release of tumor fighting cytokines.
    • Nathan Goodyear
       
      Th1 cells stimulate NK and other tumor fighting macrophages via IL-2 and IL-12; In contrast, Th2, which is stimulated in allergies and parasitic infections, produce IL-4 and IL-10.  IL-4 and IL-10 inhibit TH-1 activation and the histamine released from mast cell degranulation upregulates T suppressor cells to further immune suppression.
  • Th-2 subset of lymphocytes, on the other hand are activated in allergies and parasitic infections to release Interleukin-4 and Interleukin-10
  • These have respectively inhibitory effects on iNOS and lymphocyte Th-1 activation
  • Mast cells contain histamine which when released increases the T suppressor cells, to lower the immune system and also acts directly on many tumor Histamine receptors to stimulate tumor growth
  • Tumor cells release IL-10, and this is thought to be one of the important areas of Th-1 suppression in cancer patients
  • IL-10 is also increased in cancer causing viral diseases such as HIV, HBV, HCV, and EBV
  • IL-10 is also a central regulator of cyclooxygenase-2 expression and prostaglandin production in tumor cells stimulating their angiogenesis and NO production
  • nitric oxide in tumor cells even prevents the activation of caspases responsible for apoptosis
    • Nathan Goodyear
       
      NO produced by cancer cells inhibits proapoptotic pathways such as the caspases.
  • early stages of carcinogenesis, which we call tumor promotion, one needs a strong immune system, and fewer oxygen radicals to prevent mutations but still enough to destroy the tumor cells should they develop
  • later stages of cancer development, the oxygen radicals are decreased around the tumors and in the tumor cells themselves, and the entire cancer fighting Th-1 cell replication and movement are suppressed. The results are a decrease in direct toxicity and apoptosis, which is prevented by NO, a suppression of the macrophage and leukocyte toxicity and finally, a suppression of the T-cell induced tumor toxicity
  • cGMP is increased by NO
  • NO in cancer is its ability to increase platelet-tumor cell aggregates, which enhances metastases
  • the greater the malignancies and the greater the metastatic potential of these tumors
  • The greater the NO production in many types of tumors,
  • gynecological
  • elevated lactic acid which neutralizes the toxicity and activity of Lymphocyte immune response and mobility
  • The lactic acid is also feeding fungi around tumors and that leads to elevated histamine which increases T-suppressor cells.  Histamine alone stimulates many tumor cells.
    • Nathan Goodyear
       
      The warburg effect in cancer cells results in the increase in local lactic acid production which suppresses lymphocyte activity and toxicity as well as stimulates histamine production with further stimulates tumor cell growth.
  • T-regulatory cells (formerly,T suppressor cells) down regulate the activity of Natural killer cells
  • last but not least, the Lactic acid from tumor cells and acidic diets shifts the lymphocyte activity to reduce its efficacy against cancer cells and pathogens in addition to altering the bacteria of the intestinal tract.
  • intestinal tract bacteria in cancer cells release sterols that suppress the immune system and down regulate anticancer activity from lymphocytes.
  • In addition to the lactic acid, adenosine is also released from tumors. Through IL-10, adenosine and other molecules secreted by regulatory T cells, the CD8+ cells can be inactivated to an anergic state
  • Adenosine up regulates the PD1 receptor in T-1 Lymphocytes and inhibits their activity
  • Adenosine is a purine nucleoside found within the interstitial fluid of solid tumors at concentrations that are able to inhibit cell-mediated immune responses to tumor cells
  • Adenosine appears to up-regulate the PD1 receptor in T-1 Lymphocytes and inhibits the immune system further
  • Mast cells with their release of histamine lower the immune system and also stimulate tumor growth and activate the metalloproteinases involved in angiogenesis and metastases
  • COX 2 inhibitors or all trans-retinoic acid
  • Cimetidine, an antihistamine has been actually shown to increase in apoptosis in MDSC via a separate mechanism than the antihistamine effect
    • Nathan Goodyear
       
      cimetidine is an H2 blocker
  • interleukin-8 (IL-8), a chemokine related to invasion and angiogenesis
  • In vitro analyses revealed a striking induction of IL-8 expression in CAFs and LFs by tumor necrosis factor-alpha (TNF-alpha)
  • these data raise the possibility that the majority of CAFs in CLM originate from resident LFs. TNF-alpha-induced up-regulation of IL-8 via nuclear factor-kappaB in CAFs is an inflammatory pathway, potentially permissive for cancer invasion that may represent a novel therapeutic target
  •  
    Great review of the immunosuppression in cancer driven by the likes of NO.
ramanshail17

How to Improve Concentration and Memory Power - 0 views

  •  
    Few instances are common in everyone's life when your lack of concentration begins to take a toll on your professional as well as personal life. What could be done to improve concentration and memory? Let us decode this quest today in this article.
KELLY147

How to use Artificial Intelligence in Fintech for decisive experience - 0 views

  •  
    As the FinTech industry has a widespread reach globally, AI is allowed to upsurge several new opportunities. Thus, the benefits of using AI in the financial sector are wide-ranging and recurring. From bank service marketing to handling customer queries, FinTech companies are introducing AI-enabled services.
« First ‹ Previous 341 - 360 of 391 Next › Last »
Showing 20 items per page