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Nathan Goodyear

Decline in semen concentration and morphology in a sample of 26 609 men close to genera... - 0 views

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    Retrospective study of 26,609 men found a 1.9% annual decline in sperm concentration, increase in abnormal morphology percentage.
Nathan Goodyear

Cardiovascular disease in Europe: epidemiological update 2016 | European Heart Journal ... - 0 views

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    Cancer will soon overtake cardiovascular disease as the #1 cause of mortality in the US and worldwide as happened in 12 European countries. The current dogma for cancer treatment is not working; the goal must be prevention. The 12 countries include: Spain, France, Belgium, Denmark, Italy, Israel, Luxembourg, The Netherlands, Norway, Portugal, Slovenia, and UK.
alexabert

for my project - 0 views

HELLO For my donation project, you may be the person I need. In short, my name is Alexandrea BERTUZZI, of Italian origin, but under medical observation in France. I suffer from a serious illness wh...

started by alexabert on 27 Jun 20 no follow-up yet
Jackson Samuel

Small breakthroughs offer big hope of AIDS 'cure' - 0 views

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    Small but significant breakthrough studies on people who have been able to overcome or control HIV were presented at a major world conference on ways to stem the three-decade-old disease. One study focused on a group of 12 patients in France who began treatment on antiretroviral drugs within 10 weeks of becoming infected with human immunodeficiency virus, but then stopped the therapy after nearly three years.
Nathan Goodyear

Testosterone: More Than Having the Guts to Win the Tour de France - 0 views

  • female adult mice have microbiomes similar to those of prepubescent mice of both sexes;
  • the commensal microbial community in adult male mice significantly deviates from this shared initial pool.
  • the microbiome in castrated adult males clearly shifts away from that of normal adult males and is closer to the microbiome of females
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  • The incidence of T1D in these mice is positively correlated with the “femaleness” of the microbiota
  • These results support the hypothesis that the host androgen level is influential in determining the composition of the microbiota, which in turn affects T1D initiation and progression
  • a high testosterone level enriches the microbiota for specific organisms such as segmented filamentous bacteria (SFB) and Escherichia coli or Shigella–like (SECS) strains.
  • A minimum level of testosterone and specific male-enriched microbes working together upregulate M2 macrophage and IFN-γ producing T cells in pancreatic lymph nodes. Microarray data show that both the IFN-γ and IL-1β pathways are also stimulated.
  • These microbes also upregulate host testosterone
  • In four independent experiments, the authors found no universal unique “male microbiome”
  • they did find that four distinct combinations of microbial groupings (with an interesting lack of overlap at the individual family level in the four experiments) were enhanced by androgen
  • one species consists of the segmented filamentous bacteria (SFB) and belongs to the Firmicutes, whereas the other is an Escherichia coli or Shigella–like (SECS) strain belonging to the Proteobacteria
  • colonization with protective microbiomes—e.g., SPF microbiota, SFB, and SECS—is positively correlated with high blood testosterone levels in male mice
  • A direct implication of this study is that probiotic administration or fecal transplantation is a theoretically possible approach to protection against T1D
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    nice summary of article on the relationship between Testosteorne and gut microbiome in autoimmune disease.
Nathan Goodyear

Delayed-Onset Hemolytic Anemia in Patients with Travel-Associated Severe Malaria Treate... - 0 views

  • delayed hemolytic events occur in ≈20% of patients with severe imported malaria, and 60% of these patients require blood transfusion
  • Delayed-onset anemia (herein referred to as postartesunate delayed-onset hemolysis [PADH] pattern of anemia) has been observed to occur 2–3 weeks after initiation of IV artesunate
  • The mechanism of this anemia is hemolytic, as demonstrated by high serum lactate dehydrogenase (LDH) and low plasma haptoglobin levels
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  • this side effect is associated with artesunate
  • PADH occurred in 27% of patients in this study, but it was rarely associated with severe anemia and was never fatal
  • median delayed drop in hemoglobin levels was 1.3 g/dL
  • This transfusion rate (<5%) is markedly lower than that previously reported for patients with severe imported malaria and delayed-onset anemia (≈60%)
  • Side effects of artesunate frequently include gastrointestinal disturbances, neutropenia (1.3%), reticulocytopenia (0.6%), and elevated liver enzymes (1.1%)
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    artesunate
indiacardiacsurg

French Health Trip To India: Le meilleur cardiologue interventionnel en Inde ... - 0 views

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    L'ambition du meilleur cardiologue interventionnel de l'Inde dans la vie est de fournir les meilleurs établissements de soins cardiaques aux gens ordinaires du pays à moindre coût. Vous pouvez nous envoyer un e-mail- drtskler@indiacardiacsurgerysite.com ou nous appeler au +91-9096436224
indiacardiacsurg

Les meilleurs chirurgiens de remplacement de la valve aortique en Inde sur lesquels vou... - 0 views

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    Le coût moyen de la chirurgie de remplacement de la valve aortique en Inde est généralement de 20 à 50 % inférieur à celui d'un traitement équivalent en Occident. Ce coût moyen de la chirurgie de remplacement de la valve aortique en Inde laisse au visiteur médical un budget pour la récupération ou même les loisirs. Appelez-nous au +91-9370586696 ou écrivez-nous à : enquiry@indiacardiacsurgerysite.com
indiacardiacsurg

French Health Trip To India: Un chirurgien cardiaque pour enfants en Inde cré... - 0 views

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    De plus, le chirurgien cardiaque pour enfants en Inde offre un taux de réussite de 99,6% car il est effectué à l'aide de la technologie la plus avancée, à la hauteur de ce que possèdent même les pays les plus évolués du monde. Obtenez une réponse rapide aux requêtes, appelez-nous simplement au +91-9370586696 ou par e-mail : enquiry@indiacardiacsurgerysite.com
spineneuro

French to India Medical Travel: Revenez à une vie de qualité avec les chirurg... - 0 views

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    Les chirurgiens indiens du rachis cervical ont une expérience et des compétences reconnues dans le monde entier pour la chirurgie de la laminoplastie cervicale. Des patients du monde entier viennent en Inde en raison de l'intérêt thérapeutique des 10 meilleurs chirurgiens de la colonne cervicale en Inde ou en raison de l'offre médicale plus élevée des chirurgiens de la colonne cervicale indiens qui pratiquent ces chirurgies aux taux les plus modérés. Cliquez ici pour un rendez-vous rapide ou appelez le +91-98604-32255 ou envoyez un courriel à enquiry@spineandneurosurgeryhospitalindia.com
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