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Recliner Wheelchair - 0 views

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    Reclining wheelchairs, since the product class is built around one key feature: the capability to adjust the backrest and/or footrest into a reclined position. This feature is especially important to users who find it difficult or impossible to sit in a fully upright position, and users who sleep in their chairs frequently. For those that are looking for a more portable chair. When compared with a similar, non-reclining chair, a reclining wheelchair tends to weigh more and - unlike other manual models - manual wheelchairs that recline typically aren't foldable. reclining wheelchair compensates mechanically for body positioning by automatically readjusting armrests and lateral supports.

    Recliner wheelchair is low profile allowing to comfortably fit under tables and desks. Enjoy numerous activities with increased comfort such as stretching, napping and watching television. The ability to recline also improves circulation and the ability for sore spots to heal.

    Karma Reclining Wheelchair KM 5000:
    The karma reclining wheelchair km-5000 Transport Wheelchair is an ultra lightweight folding aluminum reclining wheelchair. With full length padded armrests, an adjustable height head pillow, and more this wheelchair has added comfort for any user. This chair also features swing-away elevating footrests and adjustable length leg supports and footplates. With a weight of 33 Lbs this chair can be transported with ease.

    Karma Reclining Wheelchair KM 5000 Features:
    Folding 6061 T-6 Aircraft-grade aluminum frame in black
    powder coat finish
    Backrest Reclines 90°~163° and includes anti-tippers
    Full length padded detachable armrests with side panels
    Swing-away detachable elevating footrests
    Adjustable length leg supports & footplates
    Adjustable-height head pillow
    14" Mag wheels with flat free polyurethane tires
    7" x 1" Flat free front polyurethane casters
    Adjustab
Nathan Goodyear

Urinary estrogens and estrogen metabolites and subsequent risk of breast cancer among p... - 0 views

  • While the catechol estrogens have estrogenic and genotoxic potential, the methylated catechol estrogens, which are catechol estrogens with one hydroxyl group methylated, have been hypothesized to lower risk of breast cancer.
  • Despite the estrogenic and genotoxic potential of many of the EM, we only observed a significantly increased breast cancer risk with one EM, 17-epiestriol, which has particularly strong estrogenic activity and binds to both ERα and ERβ with an affinity comparable to estradiol
  • We did not observe reduced risk for higher concentrations of 2-pathway EM relative to 16-pathway EM, nor did we observe a consistent benefit of higher concentrations of methylated catechol EM compared with catechol EM.
  • ...4 more annotations...
  • EM also can be genotoxic, but the individual EM vary in their ability to induce DNA damage
  • Catechol estrogens can be oxidized into quinones and induce DNA damage directly through the formation of DNA adducts, or indirectly via redox cycling and generation of reactive oxygen species
  • the oxidized forms of the catechol estrogens differ in their ability to damage DNA through adducts, with oxidized 2-catechols forming stable and reversible DNA adducts and oxidized 4-catechols forming unstable adducts, which lead to depurination and mutations
  • 2- and 4-catechols have been shown to produce reactive oxygen species and induce oxidative DNA damage (46). These catechols also induce neoplastic transformation in ER-cells, and thus act independently from the ER
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    Estrogen metabolites.
Nathan Goodyear

Salivary cortisol for assessment of hypothalamic-p... [Neuroimmunomodulation. 2009] - P... - 0 views

  • Sampling for salivary cortisol determination is a sensitive, specific and pain-free procedure and it is therefore very useful for following healthy and sick children before, during and after pharmacological interventions
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    Salivary cortisol for assessment of hypothalamic-pituitary-adrenal axis function.
Nathan Goodyear

Omega Research - 0 views

  • These data have important implications for the supplementation of a combination of omega-3 fatty acids and antioxidants in the successful management of female infertility.
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    omega 3 and antioxidants aid in infertility
Nathan Goodyear

The Toxicology of Mercury - Current Exposures and Clinical Manifestations - NEJM - 0 views

  • The Toxicology of Mercury — Current Exposures and Clinical Manifestations
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    Nice review of the toxicology of Mercury
Nathan Goodyear

TACA Talk About Curing Autism - Gluten-free, Casein-free (GFCF) Diet - Hidden Sources o... - 0 views

  • Hidden Sources of Gluten
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    Hidden Sources of Gluten
Nathan Goodyear

TSH is a poor measure of severity of tissue hypothyroidism - 0 views

  • Thyroid stimulating hormone (TSH) tests are not useful for estimating the clinical and metabolic severity of primary overt thyroid failure. Meier and colleagues (p311) found that, in contrast with the accuracy of serum TSH measurement in the early diagnosis of hypothyroidism, clinical markers and circulating thyroid hormones much more accurately reflect the degree of tissue hypothyroidism. Initiation of replacement therapy should be guided by clinical presentation and circulating thyroid hormones and not by TSH concentrations
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    TSH is not a useful test
Nathan Goodyear

Occupational Safety and Health Guideline for Xylene - 0 views

  • * Signs and symptoms of exposure
  • EXPOSURE SOURCES AND CONTROL METHODS
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    everything you wanted to know about the toxin xylene
Nathan Goodyear

Type 1 diabetes associated with acquired generaliz... [J Clin Endocrinol Metab. 2008] -... - 0 views

  • Acquired generalized lipodystrophy (AGL) is marked by severe insulin resistance and hypertriglyceridemia. Rarely, AGL and type 1 diabetes (T1D) coexist.
  • Long-term recombinant leptin therapy is effective in treating the insulin resistance of patients with the unusual combination of T1D and AGL.
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    leptin useful in severe insulin resistance, hypertriglyceridemia and type 1 Diabetes
Nathan Goodyear

Overexpression of SIRT1 Protects Pancreatic β-Cells Against Cytokine Toxicity... - 0 views

  • SIRT1, a class III histone/protein deacetylase, is known to interfere with the nuclear factor-κB (NF-κB) signaling pathway and thereby has an anti-inflammatory function
  • central role of NF-κB in cytokine-mediated pancreatic β-cell damage
  • SIRT1 as a possible target to attenuate cytokine-induced β-cell damage.
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    SIRT1 as possible target to reduce pancreatic inflammation and thus prevent/reduce diabetes;  Oh by the way Resveratrol acts at SIRT1
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