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Nathan Goodyear

Comparison of Blood and Brain Mercury Levels in Infant Monkeys Exposed to Methylmercury... - 0 views

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    Animal study finds that methyl Hg is not useful in determining effects of ethyl mercury.  According to this study, the conclusion is that the ethyl Mercury from Thimerosal is converted to inorganic Hg as evident in the results.  So, in essence, the ethyl mercury, considered less toxic than methyl mercury, is converted to inorganic Mercury a more toxic compound.  The results of the study revealed a higher % of inorganic Hg in the brains of those exposed to thimerosal to those exposed to methylMercury.
Nathan Goodyear

Lasting neuropathological changes in rat brain aft... [Folia Neuropathol. 2010] - PubMe... - 0 views

  • Thimerosal, an organomercurial
  • Numerous neuropathological changes were observed in young adult rats which were treated postnatally with thimerosal
  • hese findings document neurotoxic effects of thimerosal, at doses equivalent to those used in infant vaccines or higher, in developing rat brain, suggesting likely involvement of this mercurial in neurodevelopmental disorders.
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    Mercury from thimerosal shown to have serious neuopathological changes in the brain
Nathan Goodyear

Mercury Levels in Newborns and Infants After Receipt of Thimerosal-Containing Vaccines - 0 views

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    good letter to the editor on the accumulation of inorganic Hg in the brain from Thimerosal.
Nathan Goodyear

Notice to Readers: Thimerosal in Vaccines: A Joint Statement of the American Academy of... - 0 views

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    CDC's call for removal of Thimerosal from vaccines was in 1999; yet still exists in flu vaccines some 12 years later: why?
Nathan Goodyear

Thimerosal and the Occurrence of Autism: Negative Ecological Evidence From Danish Popul... - 0 views

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    Danish study that had data altered prior to publication.  The original data showed decreasing Autism rate in Danish children after removal of thimerosal from their vaccines
Nathan Goodyear

Sex-dependent changes in cerebellar thy - PubMed Mobile - 0 views

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    Thimerosal shown to disrupt thyroid gene expression in rat model.
Nathan Goodyear

1210_article_14 - 0 views

  • These modulatory effects - which most likely involve binding with functional thiol residues - are interwoven with neurotoxic actions of both mercurials.
  • THIM is metabolized in the body to ethyl mercury (EtHg) and subsequently to inorganic mercury forms, which accumulate in tissues of vital organs, including the brain (22). Information about neurochemical and neurotoxic effects of THIM is still limited, but the existing data indicate that in pharmacodynamics and toxicity THIM/EtHg does not differ significantly from methyl mercury (MeHg), which has been studied more extensively, although these compounds differ somewhat in pharmacokinetics (8).
  • Several studies documented that the neurotoxic effects of mercurials involve glutamate-mediated excitotoxicty, due to their ability to inhibit uptake of glutamate in astrocytes, resulting in an increase of the extracellular level of this excitatory amino acid
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    neurotoxic effects of thimerosal
Nathan Goodyear

Early Thimerosal Exposure and Neuropsychological Outcomes at 7 to 10 Years - NEJM - 0 views

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    Increasing mercury exposure associated with increasing tics in children.
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