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arunaraayala

Forlan forever provides solutions: Jackichand Singh - Locality News - 0 views

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    On October twenty, the Indian team achieved its best FIFA ranking (137) in over six years. The increase was propelled by India's 4-1 ending over higher hierarchal Puerto RICO Act. One among the scorers within the game was Mumbai town FC's Jackichand Singh
indiacardiacsurg

Dr Trehan Cardiologist Delhi Performs First Endoscopic "Triple Valve" Surgery - 101 Pre... - 0 views

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    Singh was treated in the cardiac intensive care unit at Medanta, throughout which her valve disorder was identified and surgery planned. On Nov 12, Singh became the first endoscopic triple valve surgery patient in India. Dr. Trehan Cardiologist Delhi has successfully executed the India's first-ever endoscopic "triple valve" surgery at Medanta Gurgaon Delhi. Dr. Naresh Trehan For Appointment: +91-9370586696
Nathan Goodyear

Sex hormones in head and neck cancer: Current knowledge and perspectives Singh HP, Kuma... - 0 views

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    Sex hormones in head and neck cancer.  The jury is still out and probably follows other hormone sensitive cancers.  
Nathan Goodyear

Implications of free radicals and antioxidant levels in carcinoma of the breast: A neve... - 0 views

  • Experimental investigations as well as clinical and epidemiological findings have provided evidence supporting the role of reactive oxygen metabolites or free radicals such as singlet oxygen O 2 - , superoxide anions (O 2 ), hydrogen peroxide (H­2 O2 ) and hydroxyl radical in the etiology of cancer.
  • Certain aldehydes such as Malonyldialdehyde (MDA), the end product of lipid peroxidation arising from free radical degeneration of polyunsaturated fatty acids can cause cross linking in lipids, proteins and nucleic acids leading to cellular damage.
  • In this study, patients with cancer exhibited higher levels of MDA, both in tissues and serum (p<0.001) compared to the control group [Table 1]. In tissue, the MDA level in stage IV was significantly higher as compared to stage I indicating increased free radical activity with increasing severity of cancer
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  • From these observations, it can be concluded that MDA levels play an important role in assessing the outcome of cancer
  • SOD and CAT are considered primary antioxidant enzymes, since they are involved in direct elimination of reactive oxygen metabolites. [13-16] They also act as anti-carcinogens and inhibitors at initiation and promotion/transformation stage in carcinogenesis
  • In our study, SOD and CAT levels were found to be low in all cancer patients as compared to controls
  • Fridovich and Tayarani have demonstrated in their respective studies that the reduction in SOD activity increases the toxic effects of O2 - and this might lead to severe cellular damage.
  • Mehrotra et al. in their study also observed high levels of MDA and low levels of SOD and CAT in patients of cancer cervix which is in sync with our observations.
  • strong evidence regarding the definitive role of free radicals in breast malignancy.
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    This study finds a strong correlation between advancing breast cancer, decreased catalase and SOD with increasing MDA.  The authors of this study conclude this is a key factor in carcinogenesis and not a by-product of cancer.  This flies in the face of traditional medicines fear of antioxidant therapy in cancer.
Nathan Goodyear

Elevated Levels of Measles Antibodies in 68 7 8 Children with Autism - 0 views

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    Antibodies to vaccine strain measles virus found in children with Autism. However, this was not found in siblings.
Nathan Goodyear

Phenotypic expression of autoimmune autistic disorder (AAD): A major subset of autism - 0 views

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    This study proposes an autoimmune component of ASD. The proposed autoimmunity is from the presence of vaccine strain measles virus. Excessive inflammation plays role in this proposed autoimmunity. Samples in this study were taken from serum and CSF
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