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Nathan Goodyear

Adipose Tissue Recruitment of Leukocytes - 0 views

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    good discussion on how adipose tissue recruits macrophages and increases inflammatory signaling initiating insulin resistance.  This reveals how adipose tissue is extremely active.
Nathan Goodyear

ingentaconnect Adipose Tissue Macrophages, Low Grade Inflammation and Insulin Re... - 0 views

  • “M1” or “classically activated” macrophages
  • PPAR-gamma agonists
  • “M2” or an “alternatively activated” anti-inflammatory phenotype
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    ATMs and obesity induced inflammation initiates insulin resistance and thus type II diabetes. The bodies reaction to a fat cell is no different than a bacterial, viral, or parasitic infection.  The body recognizes something (fat) that shouldn't be there and it attempts to destroy it and remove it.
Nathan Goodyear

Tumour-Associated Macrophages (TAMs) in Colon Cancer and How to Reeducate Them - 0 views

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    Great review of TAMs and the benefit to the TME.
Nathan Goodyear

Frontiers | Reprogramming of Tumor-Associated Macrophages with Anticancer Therapies: Ra... - 0 views

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    Chemotherapy and radiation induce M2 macrophage polarization favoring metastasis.
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