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Nathan Goodyear

Creatine supplementation lowers brain glutamate levels in Huntington's disease. - PubMe... - 0 views

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    Creatine helpful in decreasing glutamate levels in Huntington's disease.
Nathan Goodyear

Mitochondria: a therapeutic target in neurodegener... [Biochim Biophys Acta. 2010] - Pu... - 0 views

  • mitochondrial dysfunction has a central role in the pathogenesis of Alzheimer's, Parkinson's and Huntington's diseases and amyotrophic lateral sclerosis
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    mitochondrial dysfunction has a central role in the pathogenesis of Alzheimer's, Parkinson's and Huntington's diseases and amyotrophic lateral sclerosis
Nathan Goodyear

Study Suggests Coenzyme Q10 Slows Functional Decline in Parkinson's Disease: National I... - 0 views

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    high dose CoQ10 shown to slow disease progression in Parkinson's disease.  A similar study had shown the same finding in Huntington's disease.  Both are excitotoxic diseases
Nathan Goodyear

Coenzyme Q10 effects in neurodegenerative disease. [Neuropsychiatr Dis Treat. 2009] - P... - 0 views

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    CoQ10 shown to be beneficial in treatment of neurodegenerative diseases, Parkinson's, Alzheimer's, ALS, Huntington's, in animal models
Nathan Goodyear

Coenzyme Q10 as a possible treatment for neurodege... [Free Radic Res. 2002] - PubMed r... - 0 views

  • CoQ10 can significantly extend survival, delay motor deficits and delay weight loss and attenuate the development of striatal atrophy in a transgenic mouse model of HD
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    CoQ10 shown to shown to slow progression of the neurodegenerative disease: Huntington's disease
Nathan Goodyear

Mitochondrial dynamics in cell death and neurodege... [Cell Mol Life Sci. 2010] - PubMe... - 0 views

  • abnormal mitochondrial dynamics relevant to neuronal synaptic loss and cell death in neurodege
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    Mitochondrial dynamics in cell death and neurodegeneration.
Nathan Goodyear

Coenzyme Q treatment of neurodegenerative diseases... [Mitochondrion. 2007] - PubMed re... - 0 views

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    CoQ10 shows promise in neurodegenerative disorders
Nathan Goodyear

Mitochondria, metabolic disturbances, oxidative st... [J Neurol Sci. 2007] - PubMed result - 0 views

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    Great article on CoQ10, mitochondrial function, the kynurenine system and neurodegenerative diseases
Nathan Goodyear

Oxidative stress and neurotoxicity. [Chem Res Toxicol. 2008] - PubMed result - 0 views

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    Great article on how oxidative stress, and thus mitochondrial dysfunction, are at the core of neurodegenerative diseases
Nathan Goodyear

Mitochondrial DNA damage and repair in neurodegene... [DNA Repair (Amst). 2008] - PubMe... - 0 views

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    mitochondria dysfunction at core of aging and neurodegenerative disease
Nathan Goodyear

SpringerLink - NeuroMolecular Medicine, Volume 10, Number 4 - 0 views

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    nice discussion of mitochondria and their implication in aging and neurodegenerative disease
Nathan Goodyear

Glutamate and the glutamate receptor system: a tar... [Int J Geriatr Psychiatry. 2003] ... - 0 views

  • Under certain conditions, glutamate has a toxic action resulting from an activation of specific glutamate receptors, which leads to acute or chronic death of nerve cells.
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    deep, heavy read on glutamate excitotoxicity and neuronal death leading to neurodegenerative disease
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