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Neuroprotective Sirtuin ratio reversed by ApoE4
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www.pnas.org/...1314145110.abstract
ApoE4
alzheimer's disease
Alzheimer's
disease
sirtuins
SIRT1
resveratrol
shared by
Nathan Goodyear
on 23 Oct 13
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Nathan Goodyear
on 23 Oct 13
ApoE4 allele is known to increase Alzheimer's disease by 10 fold. One mechanism is through a lowering of SirT1 and an increase in the SirT1:SirT2 ratio. This SirT1 is the target of resveratrol in red wine.
ApoE4 allele is known to increase Alzheimer's disease by 10 fold. One mechanism is through a lowering of SirT1 and an increase in the SirT1:SirT2 ratio. This SirT1 is the target of resveratrol in red wine.
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Better memory functioning associated with higher total and LDL cholesterol levels in ve...
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www.ncbi.nlm.nih.gov/...PMC2614555
cholesterol
LDL
brain
neurology
memory
levels
elderly
shared by
Nathan Goodyear
on 19 Jun 12
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Nathan Goodyear
on 19 Jun 12
higher total cholesterol and LDL associated with better memory in the elderly population. This was present in those without APOE4 allele
higher total cholesterol and LDL associated with better memory in the elderly population. This was present in those without APOE4 allele
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Apolipoprotein E and Alzheimer disease: risk, mechanisms, and therapy
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www.ncbi.nlm.nih.gov/...PMC3726719
ApoE
ApoE4
alzheimer
Alzheimer's disease
brain health
shared by
Nathan Goodyear
on 08 Dec 17
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Nathan Goodyear
on 08 Dec 17
Great review on APOE and its contribution to Alzheimer's disease risk.
Great review on APOE and its contribution to Alzheimer's disease risk.
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