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Come work with us Interested in working with researchers from different disciplines within the Harvard, MIT and Broad community and an unique opportunity to participate in world-class research to make an impact on human health? Come work with us! We are looking for a computational biologists to handle data from a wide variety of experimental methods, focusing on next-gen sequencing technologies. Keep Reading...  SCDE is live The Stem Cell Discovery Engine (SCDE) is an integrated platform that allows users to consistently describe, share and compare cancer and tissue stem cell data. It is made up of an online database of curated experiments coupled to a customized instance of the Galaxy analysis engine with tools for gene list manipulation and molecular profile comparisons. The SCDE currently contains more than 50 stem cell-related experiments. Each has been manually curated and encoded using the ISA-Tab standard to ensure the quality of the data and its annotation. Keep Reading...  The Center for Health Bioinformatics at the Harvard School of Public Health provides consults to researchers for the management, integration and contextual analysis of biological high-throughput data. We are a member of the Center for Stem Cell Bioinformatics, the Environmental Statistics and Bioinformatics Core at the Harvard NIEHS Center for Environmental Health and the Genetics & Bioinformatics Consulting group for Harvard Catalyst and work closely with our colleagues in the Department of Biostatistics and the Program in Quantitative Genomics to act as a single point of contact for computational biology,

"Evolution likes to keep what works best. The rest falls by the wayside. In theory, this means that the most "fit" variations, say, a color that looks poisonous or one particularly attractive to the ladies, would become the most common. By this logic, the many colors of the guppy should have conformed to a single common pattern long ago. But they haven't. Instead, the male guppies continue to show not only bright colors but also a high diversity of colors. What keeps the variety going? The rare-male effect. Female guppies prefer the males that are rare, no matter what their color pattern actually is. This effect has been documented in the laboratory in guppies and in other species like fruit flies."

Pests can cause significant problems in homes, ranging from property damage to health hazards. Unfortunately, Texas is home to a variety of pests, such as cockroaches, ants, rodents, and termites, that can cause severe damage if not controlled. In this article, we will provide a guide to pest control services in TX to help homeowners keep their homes safe from pests.

Making a public commitment to your goals reduces motivation.

"uBiome is a citizen science project that allows the public access to cutting edge sequencing technology to understand their health through the microbiome. How does the microbiome affect my health? We are all covered in trillions of microbes -- in fact, they outnumber human cells 10:1. The trillions of bacteria live on and in us are collectively called the microbiome. Like the rainforest, the healthy human microbiome is a balanced ecosystem. The correct balance of microbes keeps potential pathogens in check and regulates our immune system. Microbes also perform essential functions such as digesting food and synthesizing vitamins. Studies have also linked the microbiome to human mood and behavior, as well as many gut disorders, eczema, and chronic sinusitis."

"In short, this site is a record of my learning process as I try to understand aspects of colony health and productivity, and the reasons why various management techniques work (or don't). If you are a beginning beekeeper looking for basic information, or an experienced beekeeper looking for a summary of mite treatment options, I suggest that you go directly to Basic Beekeeping. I started keeping bees as a hobbyist in 1967, and then went on to get university degrees in biological sciences, specializing in entomology. In 1980 I began to build a migratory beekeeping operation in California, and currently run about 1000 hives with my two sons, from which we make our livings. In 1993, the varroa mite arrived in California, and after it wiped out my operation for the second time in 1999, I decided to "hit the books" and use my scientific background to learn to fight back"

"Hudnall: I really do believe that repression makes you sick. I'm big believer of what is coming out in the neuroscience and therapy community. Brene Brown, who is a shame and guilt expert, said it best: "We have an epidemic of shame in this country." If you keep things inside and have no one to talk to - and this is not crystals and patchouli - you will get sick, you will be miserable, you will ruin your relationships, and you will be unhappy. I know people whose lives were ruined by silence. Especially women. The one thing that has really opened my eyes while teaching is just what we do to our women. Only my women students have said to me, "I don't know if I have anything worth saying." It smacks me in the face every day. We are really fucking up our women"

"Note that the antimicrobial peptides are produced largely in the fat bodies-so there would be less of this sort of response in forager bees, which don't maintain their fat bodies. This makes sense, since foragers aren't expected to live for long. However, keep in mind that the bees in protein-hungry colonies are unable to develop their fat bodies fully-this one point where nutrition ties in to immunity. Surprisingly, Jay Evans found that these genes are not upregulated in bees from CCD colonies, even though the bees are full of pathogens! There are a few potential explanations for this finding that come to mind: The bee hemocytes are not recognizing the pathogens as foreign (suppression of recognition systems, perhaps by viruses?). The colonies could be protein-starved. Something is suppressing the transcription of the genes, or their translation to peptides. Note that viruses can do this very thing, which I feel may be a big clue!"

In a recent study, researchers show that a gene called DMRT1 found only on the Z chromosome partly explains bird "maleness". When a ZZ embryo gets less DMRT1, the embryos start to take on some female traits. These studies show us that bird gender can be partly explained by genetics. Not having enough of a single gene can keep a bird from becoming a bona fide male bird. But this doesn't rule out the possibility of a female gene being on the W chromosome. Scientists just haven't yet found one.

A thought to keep in mind as you read this - what happens to the already overburdened graduate whose job gets outsourced, and then can't find another because he's deemed "overqualified" for the low skilled, low wage jobs available? Answer: Look up "capitalization of interest" and then note that one can't erase student loan debt by declaring bankruptcy. What will result will be the mathematical equivalent of charging compound interest on a loan that the graduate has been deprived of the means of repaying.

Telomeres, the repetitive sequences of DNA at the ends of linear chromosomes, have an important function: They protect vulnerable chromosome ends from molecular attack. Researchers at Rockefeller University now show that telomeres have their own weakness. They resemble unstable parts of the genome called fragile sites where DNA replication can stall and go awry. But what keeps our fragile telomeres from falling apart is a protein that ensures the smooth progression of DNA replication to the end of a chromosome.

"The brains of psychopaths appear to be wired to keep seeking a reward at any cost, new research from Vanderbilt University finds. The research uncovers the role of the brain's reward system in psychopathy and opens a new area of study for understanding what drives these individuals."

People keep blaming the emergence of HIV on science, or at least medicine. For the longest time this came in the form of the claim that it was all due to contaminated polio vaccine. That turned out to be factually groundless. Now a group of scientists in the US thinks it may all be down to the greatest medical intervention of all: the eradication of smallpox.

"A more potentially useful observation about HIV and viruses comes from Jennifer Smith of the University of North Carolina in Chapel Hill and colleagues in the 1 June issue of the Journal of Infectious Diseases, in which they report that men with HPV infection on their penis are nearly twice as likely to catch HIV than men without. They suspect the virus - which causes cervical cancer in women, and genital warts in men and women - attracts lymphocytes to the skin of the penis for HIV to infect, or creates micro-lesions where it can enter. That's good news, because we have a vaccine for HPV that appears to be completely safe. The team calculates that vaccinating men against HPV could prevent as many cases of HIV as more widely hailed circumcision efforts. It just goes to show that vaccination - already one of the biggest success stories of medicine - can continue to throw up unexpected benefits."

ScienceDaily (Dec. 22, 2010) - Two researchers at Albert Einstein College of Medicine of Yeshiva University have found that our 98.6° F (37° C) body temperature strikes a perfect balance: warm enough to ward off fungal infection but not so hot that we need to eat nonstop to maintain our metabolism.

MIT scientists have discovered that endothelial cells, which line the blood vessels, secrete molecules that suppress tumor growth and keep cancer cells from invading other tissues, a finding that could lead to a new way to treat cancer.

Top prevention tips worth their weight in wits for keeping your mind sharp and to enhance memory.

The hypothesis suggests that sexual reproduction via cross-fertilization keeps host populations one evolutionary step ahead of the parasites, which are frantically co-evolving to infect them. So both hosts and parasites are running (evolving) as fast as they can just to stay in the same place.

ScienceDaily (June 28, 2011) - A recent study from scientists at the Salk Institute for Biological Studies suggests that a strawberry a day (or more accurately, 37 of them) could keep not just one doctor away, but an entire fleet of them, including the neurologist, the endocrinologist, and maybe even the oncologist.

When a tube is damaged, it needs to be repaired to restore its function for better efficiency of the boiler. In that case

A simple and effective way out is the use of The Trivedi Effect®. Using positive energy to keep away insects and enhance the plant's growth, the treatment has yielded unparalleled results.