Group items tagged

Becoming Human is an interactive documentary experience that tells the story of our origins. Journey through four million years of human evolution with your guide, Donald Johanson.

""It seems to me that our three basic needs, for food and security and love, are so mixed and mingled and entwined that we cannot straightly think of one without the others." - M.F.K. Fisher Human beings are notoriously terrible at knowing when we're no longer hungry. Instead of listening to our stomach - a very stretchy container - we rely on all sorts of external cues, from the circumference of the dinner plate to the dining habits of those around us. If the serving size is twice as large (and American serving sizes have grown 40 percent in the last 25 years), we'll still polish it off. And then we'll go have dessert."

Has a cheap and effective treatment for chronic pain been lying under clinicians' noses for decades? Researchers have found that a very high dose of an opiate drug that uses the same painkilling pathways as morphine can reset the nerve signals associated with continuous pain - at least in rats. If confirmed in humans, the procedure could reduce or eliminate the months or years that millions of patients spend on pain-managing prescription drugs. The results of the study are described today in Science1.

"Our Juliets (as parents longing for grandchildren will recognize with a sigh) may experience the tumult of love for 20 years before they settle down into motherhood. And our Romeos may be poetic lunatics under the influence of Queen Mab until they are well into graduate school. What happens when children reach puberty earlier and adulthood later? The answer is: a good deal of teenage weirdness. Fortunately, developmental psychologists and neuroscientists are starting to explain the foundations of that weirdness. Photos: The Trials of Teenagers View Slideshow [SB10001424052970204573704577187080963983566] Everett Collection James Dean in the 1955 film 'Rebel Without A Cause' The crucial new idea is that there are two different neural and psychological systems that interact to turn children into adults"

"Seasonal influenza epidemics are a major public health concern, causing tens of millions of respiratory illnesses and 250,000 to 500,000 deaths worldwide each year1. In addition to seasonal influenza, a new strain of influenza virus against which no previous immunity exists and that demonstrates human-to-human transmission could result in a pandemic with millions of fatalities2. Early detection of disease activity, when followed by a rapid response, can reduce the impact of both seasonal and pandemic influenza3, 4. One way to improve early detection is to monitor health-seeking behaviour in the form of queries to online search engines, which are submitted by millions of users around the world each day. Here we present a method of analysing large numbers of Google search queries to track influenza-like illness in a population."

"Hundreds of species of bacteria call the human gut their home. This gut "microbiome" influences our physiology and health in ways that scientists are only beginning to understand. Now, a new study suggests that gut bacteria can even mess with the mind, altering brain chemistry and changing mood and behavior. In recent years, researchers have become increasingly interested in how gut bacteria might influence the brain and behavior, says John Cryan, a neuroscientist at University College Cork in Ireland. So far, most of the work has focused on how pathogenic bugs influence the brain by releasing toxins or stimulating the immune system, Cryan says. One recent study suggested that even benign bacteria can alter the brain and behavior, but until now there has been very little work in this area, Cryan says."

Cybrary Man's Educational Web Sites The internet catalogue for students, teachers, administrators & parents. Over 20,000 relevant links personally selected by an educator/author with over 30 years of experience.

"Academics have to publish in high-Impact Factor journals to receive promotions, tenure, or grant funding, and universities allocate their million-dollar library budgets to those same high-Impact Factor journals. This is despite the Impact Factor's many known flaws - the most limiting of which is that the citations it is based on take 3-5 years to accumulate"

900 years of international history from one source. Gale Digital Collections has changed the nature of research forever by providing a wealth of rare, formerly inaccessible historical content from the world's most prestigious libraries.

"Slow science was pretty much the only science conceivable for hundreds of years; today, we argue, it deserves revival and needs protection. Society should give scientists the time they need, but more importantly, scientists must take their time."

"An IEEE Spectrum contributing editor, Charette is a self-described "risk ecologist" who investigates the impact of risk on technology and society. His interest is both professional and personal: He's a 33-year member of the IEEE Computer Society and has two daughters who are contemplating STEM careers. "Now I can give better career advice to my daughters," he says"

"Everybody likes a simple cause and effect - something we can point to and say (ommitting a few choice words to the perpetrators), 'Fix this and the bees will be right again.' Reality is rarely so straightforward. As the bee decline has progressed I've lost count of the simple 'causes' that have been presented. Among the more memorable are: * mobile 'phones (the absolute 'definite cause' of choice a couple of years ago) * mobile base stations, power lines and other strong electromagnetic sources (a perennial favourite for any malaise) * alien abduction (hopefully they have smaller probes for abducted bees...) * God's punishment (pro gay-marriage states in the USA have more cases of CCD) Leo's article shows neonicotinoids are at least a plausible candidate and they are surely not good for bees, but the argument for these being the explicit 'cause' of global bee decline is still not particularly strong. The risk here is that the media and vocal lobbyists are going off on a righteous crusade to the detriment of more diligent, and maybe less newsworthy, efforts to get to the root of a complex problem. Rather than reviewing the evidence here, I recommend a visit to Randy Oliver's website where his two recent articles from the American Bee Journalon this topic can be found, along with some further commentary on his home page. Interested readers can also directly access the study by Henry et. al. (2012a), the commentry on this study by Creswell and Thompson (2012), the response to the comment (Henry et. al. 2012b) and to the meta-analysis of toxicological studies on imidacloprid by Creswell (2010). An example of one such study is Cutler and Scott-Dupree (2007). Links to all are included below. These are original material rather than reportage and demonstrate the complexity of the issue. As food for thought, I'll leave you with the following: * Neonicotinoids are widely used in Australia and our bees are not (yet) in decline."

""A ship is safe in harbor, but that's not what ships are for." By Christie Wilcox | February 14, 2013 A year and a half ago, the decision to pack up shop at ScienceBlogs and begin blogging at Scientific American was an easy one. The inimitable Bora Zivkovic had assembled a blogging dream team, a group of people I respected and admired and couldn't wait to call networkmates. Under Bora's nurturing oversight, we all have flourished, and the SciAm blog network has become the most diverse and prolific science blogging network around"

"SCinet is a high-performance network that is built, once a year, in support of the annual International Conference for High Performance Computing and Communications also known as the Supercomputing Conference. It is the primary network for the conference and is used by attendees to demonstrate and test high-performance distributed applications."

Many newly diagnosed prostate cancers present as low Gleason score tumors that require no treatment intervention. Distinguishing the many indolent tumors from the minority of lethal ones remains a major clinical challenge. We now show that low Gleason score prostate tumors can be distinguished as indolent and aggressive subgroups on the basis of their expression of genes associated with aging and senescence. Using gene set enrichment analysis, we identified a 19-gene signature enriched in indolent prostate tumors. We then further classified this signature with a decision tree learning model to identify three genes-FGFR1, PMP22, and CDKN1A-that together accurately predicted outcome of low Gleason score tumors. Validation of this three-gene panel on independent cohorts confirmed its independent prognostic value as well as its ability to improve prognosis with currently used clinical nomograms. Furthermore, protein expression of this three-gene panel in biopsy samples distinguished Gleason 6 patients who failed surveillance over a 10-year period. We propose that this signature may be incorporated into prognostic assays for monitoring patients on active surveillance to facilitate appropriate courses of treatment.

Our genetic code is translated by two super-families of modern-day enzymes. Carter's research team created and superimposed digital three-dimensional versions of the two super-families to see how their structures aligned. Carter found that all the enzymes have virtually identical cores that can be extracted to produce "molecular fossils" he calls Urzymes-Ur meaning earliest or original. The other parts, he said, are variations that were introduced later, as evolution unfolded. These two Urzymes are as close as scientists have gotten to the actual ancient enzymes that would have populated the Earth billions of years ago.

The oldest big cat fossils ever found - from a previously unknown species "similar to a snow leopard" - have been unearthed in the Himalayas. The skull fragments of the newly-named Panthera blytheae have been dated between 4.1 and 5.95 million years old. Their discovery in Tibet supports the theory that big cats evolved in central Asia - not Africa - and spread outward.

3,700 year-old store room held 2,000 liters of strong, sweet wine. Archaeologists have unearthed what may be the oldest -- and largest -- ancient wine cellar in the Near East, containing forty jars, each of which would have held fifty liters of strong, sweet wine. The cellar was discovered in the ruined palace of a sprawling Canaanite city in northern Israel, called Tel Kabri. The site dates to about 1,700 B.C. and isn't far from many of Israel's modern-day wineries.