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Erich Feldmeier

Pascal Junod » An Aspiring Scientist's Frustration with Modern-Day Academia: ... - 0 views

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    "The problem, as I see it, is that we are not doing very much to remedy these issues, and that a lot of people have already accepted that "true science" is simply an ideal that will inevitably disappear with the current system proceeding along as it is. As such, why risk our careers and reputations to fight for some noble cause that most of academia won't really appreciate anyway?"
Erich Feldmeier

The STEM Crisis Is a Myth - IEEE Spectrum - 0 views

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    "An IEEE Spectrum contributing editor, Charette is a self-described "risk ecologist" who investigates the impact of risk on technology and society. His interest is both professional and personal: He's a 33-year member of the IEEE Computer Society and has two daughters who are contemplating STEM careers. "Now I can give better career advice to my daughters," he says"
Erich Feldmeier

@5eenGeno What is wrong with our bees? - Victorian Apiarists' Association (VAA) - 0 views

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    "Everybody likes a simple cause and effect - something we can point to and say (ommitting a few choice words to the perpetrators), 'Fix this and the bees will be right again.' Reality is rarely so straightforward. As the bee decline has progressed I've lost count of the simple 'causes' that have been presented. Among the more memorable are: * mobile 'phones (the absolute 'definite cause' of choice a couple of years ago) * mobile base stations, power lines and other strong electromagnetic sources (a perennial favourite for any malaise) * alien abduction (hopefully they have smaller probes for abducted bees...) * God's punishment (pro gay-marriage states in the USA have more cases of CCD) Leo's article shows neonicotinoids are at least a plausible candidate and they are surely not good for bees, but the argument for these being the explicit 'cause' of global bee decline is still not particularly strong. The risk here is that the media and vocal lobbyists are going off on a righteous crusade to the detriment of more diligent, and maybe less newsworthy, efforts to get to the root of a complex problem. Rather than reviewing the evidence here, I recommend a visit to Randy Oliver's website where his two recent articles from the American Bee Journalon this topic can be found, along with some further commentary on his home page. Interested readers can also directly access the study by Henry et. al. (2012a), the commentry on this study by Creswell and Thompson (2012), the response to the comment (Henry et. al. 2012b) and to the meta-analysis of toxicological studies on imidacloprid by Creswell (2010). An example of one such study is Cutler and Scott-Dupree (2007). Links to all are included below. These are original material rather than reportage and demonstrate the complexity of the issue. As food for thought, I'll leave you with the following: * Neonicotinoids are widely used in Australia and our bees are not (yet) in decline."
Erich Feldmeier

@NerdyChristie "A ship is safe in harbor, but that's not what ships are for." - 0 views

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    ""A ship is safe in harbor, but that's not what ships are for." By Christie Wilcox | February 14, 2013 A year and a half ago, the decision to pack up shop at ScienceBlogs and begin blogging at Scientific American was an easy one. The inimitable Bora Zivkovic had assembled a blogging dream team, a group of people I respected and admired and couldn't wait to call networkmates. Under Bora's nurturing oversight, we all have flourished, and the SciAm blog network has become the most diverse and prolific science blogging network around"
Erich Feldmeier

THX @KasThomas , @vbioev Oral Hygiene and Cancer | Devil in the Data | Big Think - 0 views

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    "For me, the picture that emerges is one in which chronic inflammation caused by poor oral health sets the stage for more serious illness. (See my earlier post for more info about the connection between inflammation and cancer.) I think further research will probably turn up some surprising connections between oral bacteria and cancer, but we don't have to wait for additional research to begin taking oral hygiene seriously as a potential way to head off cancer and CVD."
John Smith

Webinar On Statistical Analysis of Gages - 0 views

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    The seminar begins with an examination of the fundamental vocabulary and concepts related to metrology. Topics include: accuracy, precision, calibration, and "uncertainty ratios". Several of the standard methods for analyzing measurement variation are then described and explained, as derived from AIAG's Measurement System Analysis reference book. The methods include: Gage R&R (ANOVA method, for 3 gages, 3 persons, 3 replicates, and 10 parts), Gage Correlation (for 3 gages), Gage Linearity, and Gage Bias. The seminar ends with an explanation of how to combine all relevant uncertainty information into an "Uncertainty Budget" that helps determine the appropriate width of QC specification intervals (i.e., "guard-banded specifications"). Spreadsheets are used to demonstrate how to perform the methods described during the seminar.
Erich Feldmeier

@biogarage Sick Bees - Part 3: The Bee Immune System @ Scientific Beekeeping - 0 views

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    "Note that the antimicrobial peptides are produced largely in the fat bodies-so there would be less of this sort of response in forager bees, which don't maintain their fat bodies. This makes sense, since foragers aren't expected to live for long. However, keep in mind that the bees in protein-hungry colonies are unable to develop their fat bodies fully-this one point where nutrition ties in to immunity. Surprisingly, Jay Evans found that these genes are not upregulated in bees from CCD colonies, even though the bees are full of pathogens! There are a few potential explanations for this finding that come to mind: The bee hemocytes are not recognizing the pathogens as foreign (suppression of recognition systems, perhaps by viruses?). The colonies could be protein-starved. Something is suppressing the transcription of the genes, or their translation to peptides. Note that viruses can do this very thing, which I feel may be a big clue!"
Erich Feldmeier

Light Pink 'I Want to Be a Scientist' Tee - Toddler & Girls $9.99 - 0 views

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    T-Shirt
Erich Feldmeier

Naturopathic Diaries - Confessions of a Naturopathic Doctor - 0 views

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    "Britt Marie Hermes Former naturopathic doctor and "natural health expert." Current Master's of Science student in biomedicine. I share the hard truths about naturopathic education and practice to protect patients. Please don't be fooled by natural and alternative medicine. "
The Ravine / Joseph Dunphy

Mad Science: Another Stonehenge Discovered Under Lake Michigan? | Diigo - 0 views

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    Further discussion of a fringe science article I mentioned earlier, over on the Ravine, my journal / homegroup here on Diigo.
David Corking

New Particle Collider Operating in Secret - NYTimes.com - 0 views

  • "We may not have created a black hole, but it seems we may have discovered a way for elementary particles to shape the path of evolution. You just never know what you are going to find"
    • David Corking
       
      I am no arbiter of humour, but I think this April Fool prank is fairly lame (unless there is truth in the unlikely twitter rumour that the NYT was pranked)
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    Large Hadron Collider investigative journalism
Charles Daney

Backreaction: News from Other Worlds - 0 views

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    This week, I came across some quite amazing news about planets at other stars in our galaxy. But it's not just the stories of planetary collisions and retrograde orbits that have fascinated me: It's also how all this has been learned, by closely analyzing light curves and spectra.
Charles Daney

Scientists are only two years from developing a cure for breast cancer? : Respectful In... - 0 views

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    It's just plain silly to make claims like this about a basic science paper given that, as I have discussed before, it often takes decades for basic science observations to wend their way through that long strange trip to becoming actual therapies used by clinicians. The life cycle of translational research is long, and efforts to speed it up have only met with mixed success.
Walid Damouny

If influenza was a stock, I wouldn't touch it. - 0 views

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    If influenza was a stock, I wouldn't touch it. PETER GROSS, chief medical officer at Hackensack University Medical Center in New Jersey, responding to a White House report that warned a resurgence of swine flu - or H1N1 - could kill 30,000 to 90,000 Americans this fall
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    PETER GROSS, chief medical officer at Hackensack University Medical Center in New Jersey, responding to a White House report that warned a resurgence of swine flu - or H1N1 - could kill 30,000 to 90,000 Americans this fall
Skeptical Debunker

Belief In Climate Change Hinges On Worldview : NPR - 0 views

  • "People tend to conform their factual beliefs to ones that are consistent with their cultural outlook, their world view," Braman says. The Cultural Cognition Project has conducted several experiments to back that up. Participants in these experiments are asked to describe their cultural beliefs. Some embrace new technology, authority and free enterprise. They are labeled the "individualistic" group. Others are suspicious of authority or of commerce and industry. Braman calls them "communitarians." In one experiment, Braman queried these subjects about something unfamiliar to them: nanotechnology — new research into tiny, molecule-sized objects that could lead to novel products. "These two groups start to polarize as soon as you start to describe some of the potential benefits and harms," Braman says. The individualists tended to like nanotechnology. The communitarians generally viewed it as dangerous. Both groups made their decisions based on the same information. "It doesn't matter whether you show them negative or positive information, they reject the information that is contrary to what they would like to believe, and they glom onto the positive information," Braman says.
  • "Basically the reason that people react in a close-minded way to information is that the implications of it threaten their values," says Dan Kahan, a law professor at Yale University and a member of The Cultural Cognition Project. Kahan says people test new information against their preexisting view of how the world should work. "If the implication, the outcome, can affirm your values, you think about it in a much more open-minded way," he says. And if the information doesn't, you tend to reject it. In another experiment, people read a United Nations study about the dangers of global warming. Then the researchers told the participants that the solution to global warming is to regulate industrial pollution. Many in the individualistic group then rejected the climate science. But when more nuclear power was offered as the solution, says Braman, "they said, you know, it turns out global warming is a serious problem."And for the communitarians, climate danger seemed less serious if the only solution was more nuclear power.
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  • Then there's the "messenger" effect. In an experiment dealing with the dangers versus benefits of a vaccine, the scientific information came from several people. They ranged from a rumpled and bearded expert to a crisply business-like one. The participants tended to believe the message that came from the person they considered to be more like them. In relation to the climate change debate, this suggests that some people may not listen to those whom they view as hard-core environmentalists. "If you have people who are skeptical of the data on climate change," Braman says, "you can bet that Al Gore is not going to convince them at this point." So, should climate scientists hire, say, Newt Gingrich as their spokesman? Kahan says no. "The goal can't be to create a kind of psychological house of mirrors so that people end up seeing exactly what you want," he argues. "The goal has to be to create an environment that allows them to be open-minded."And Kahan says you can't do that just by publishing more scientific data.
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    "It's a hoax," said coal company CEO Don Blankenship, "because clearly anyone that says that they know what the temperature of the Earth is going to be in 2020 or 2030 needs to be put in an asylum because they don't." On the other side of the debate was environmentalist Robert Kennedy, Jr. "Ninety-eight percent of the research climatologists in the world say that global warming is real, that its impacts are going to be catastrophic," he argued. "There are 2 percent who disagree with that. I have a choice of believing the 98 percent or the 2 percent." To social scientist and lawyer Don Braman, it's not surprising that two people can disagree so strongly over science. Braman is on the faculty at George Washington University and part of The Cultural Cognition Project, a group of scholars who study how cultural values shape public perceptions and policy
Skeptical Debunker

What causes autism? Exploring the environmental contribution : Current Opinion in Pedia... - 0 views

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    Purpose of review: Autism is a biologically based disorder of brain development. Genetic factors - mutations, deletions, and copy number variants - are clearly implicated in causation of autism. However, they account for only a small fraction of cases, and do not easily explain key clinical and epidemiological features. This suggests that early environmental exposures also contribute. This review explores this hypothesis. Recent findings: Indirect evidence for an environmental contribution to autism comes from studies demonstrating the sensitivity of the developing brain to external exposures such as lead, ethyl alcohol and methyl mercury. But the most powerful proof-of-concept evidence derives from studies specifically linking autism to exposures in early pregnancy - thalidomide, misoprostol, and valproic acid; maternal rubella infection; and the organophosphate insecticide, chlorpyrifos. There is no credible evidence that vaccines cause autism. Summary: Expanded research is needed into environmental causation of autism. Children today are surrounded by thousands of synthetic chemicals. Two hundred of them are neurotoxic in adult humans, and 1000 more in laboratory models. Yet fewer than 20% of high-volume chemicals have been tested for neurodevelopmental toxicity. I propose a targeted discovery strategy focused on suspect chemicals, which combines expanded toxicological screening, neurobiological research and prospective epidemiological studies.
Skeptical Debunker

Flightless mosquitoes developed to help control dengue fever - 0 views

  • Dengue fever causes severe flulike symptoms and is among the world's most pressing public health issues. There are 50 million to 100 million cases per year, and nearly 40 percent of the global population is at risk. The dengue virus is spread through the bite of infected female Aedes aegypti mosquitoes, and there is no vaccine or treatment. UCI researchers and colleagues from Oxitec Ltd. and the University of Oxford created the new breed. Flightless females are expected to die quickly in the wild, curtailing the number of mosquitoes and reducing - or even eliminating - dengue transmission. Males of the strain can fly but do not bite or convey disease. When genetically altered male mosquitoes mate with wild females and pass on their genes, females of the next generation are unable to fly. Scientists estimate that if released, the new breed could sustainably suppress the native mosquito population in six to nine months. The approach offers a safe, efficient alternative to harmful insecticides.
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    A new strain of mosquitoes in which females cannot fly may help curb the transmission of dengue fever, according to UC Irvine and British scientists. Great idea or frankensketter?
Skeptical Debunker

The genetic footprint of natural selection - 0 views

  • During evolution, living species have adapted to environmental constraints according to the mechanism of natural selection; when a mutation that aids the survival (and reproduction) of an individual appears in the genome, it then spreads throughout the rest of the species until, after several hundreds or even thousands of generations, it is carried by all individuals. But does this selection, which occurs on a specific gene in the genome of a species, also occur on the same gene in neighboring species? On which set of genes has natural selection acted specifically in each species? Researchers in the Dynamique et Organisation des Génomes team at the Institut de Biologie of the Ecole Normale Supérieure (CNRS/ENS/INSERM) have studied the genome of humans and three other primate species (chimpanzee, orangutan and macaque) using bioinformatics tools. Their work consisted in comparing the entire genomes of each species in order to identify the genes having undergone selection during the past 200,000 years. The result was that a few hundred genes have recently undergone selection in each of these species. These include around 100 genes detected in man that are shared by two or three other species, which is twice as many as might be anticipated as a random phenomenon. Thus a not inconsiderable proportion of the genes involved in human adaptation are also present in the chimpanzee, orangutan or macaque, and sometimes in several species at the same time. Natural selection acts not only by distancing different species from each other when new traits appear. But by acting on the same gene, it can also give rise to the same trait in species that have already diverged, but still have a relatively similar genome. This study thus provides a clearer understanding of the group of genes that are specifically implicated in human evolution (during the past 200,000 years), as it allows the identification of those genes which did not undergo selection in another primate line. An example that has been confirmed by this study is the well-known case of the lactase gene that can metabolize lactose during adulthood (a clear advantage with the development of agriculture and animal husbandry). The researchers have also identified a group of genes involved in some neurological functions and in the development of muscles and skeleton.
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    A further step has been taken towards our understanding of natural selection. CNRS scientists working at the Institut de Biologie of the Ecole Normale Supérieure (CNRS/ENS/INSERM) have shown that humans, and some of their primate cousins, have a common genetic footprint, i.e. a set of genes which natural selection has often tended to act upon during the past 200,000 years. This study has also been able to isolate a group of genes that distinguish us from our cousins the great apes. Its findings are published in PloS Genetics (26 February 2010 issue).
Skeptical Debunker

Does promiscuity prevent extinction? - 0 views

  • Known as 'polyandry' among scientists, the phenomenon of females having multiple mates is shared across most animal species, from insects to mammals. This study suggests that polyandry reduces the risk of populations becoming extinct because of all-female broods being born. This can sometimes occur as a result of a sex-ratio distortion (SR) chromosome, which results in all of the Y chromosome 'male' sperm being killed before fertilisation. The all-female offspring will carry the SR chromosome, which will be passed on to their sons in turn resulting in more all-female broods. Eventually there will be no males and the population will die out. For this study, the scientists worked with the fruitfly Drosophila pseudoobscura. They gave some populations the opportunity to mate naturally, meaning that the females had multiple partners. The others were restricted to having one mate each. They bred several generations of these populations, so they could see how each fared over time. Over fifteen generations, five of the twelve populations that had been monogamous became extinct as a result of males dying out. The SR chromosome was far less prevalent in the populations in which females had the opportunity to have multiple mates and none of these populations became extinct. The study shows how having multiple mates can suppress the spread of the SR chromosome, making all-female broods a rarity. This is because males that carry the SR chromosome produce only half as many sperm as normal males. When a female mates with multiple males, their sperm will compete to fertilise her eggs. The few sperm produced by males carrying the SR chromosome are out-competed by the sperm from normal males, and the SR chromosome cannot spread.
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    Promiscuous females may be the key to a species' survival, according to new research by the Universities of Exeter and Liverpool. Published today (25 February) in Current Biology, the study could solve the mystery of why females of most species have multiple mates, despite this being more risky for the individual.
Skeptical Debunker

Sensitive nano oscillator can detect pathogens - 0 views

  • The researchers, led by professor of applied and engineering physics Harold Craighead, made a device just 200 nanometers thick and a few microns long with an oscillating cantilever hanging off one end. (A nanometer is one-billionth of a meter; a micron is one-millionth of a meter.) They identified exactly how to tune its sensitivity -- a breakthrough that could lead to advanced sensing technologies. The experiments detailed online Feb. 8 in Journal of Applied Physics show how these oscillators, which are nanoelectromechanical systems (NEMS), could one day be made into everyday devices by lining up millions of them and treating each cantilever with a certain molecule. "The big purpose is to be able to drive arrays of these things all in direct synchrony," said first author Rob Ilic, a research associate at the Cornell NanoScale Science and Technology Facility. "They can be functionalized with different chemistries and biomolecules to detect various pathogens -- not just one thing."
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    By watching how energy moves across a tiny device akin to a springing diving board, Cornell researchers are a step closer to creating extraordinarily tiny sensors that can instantly recognize harmful substances in air or water.
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