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"Seasonal influenza epidemics are a major public health concern, causing tens of millions of respiratory illnesses and 250,000 to 500,000 deaths worldwide each year1. In addition to seasonal influenza, a new strain of influenza virus against which no previous immunity exists and that demonstrates human-to-human transmission could result in a pandemic with millions of fatalities2. Early detection of disease activity, when followed by a rapid response, can reduce the impact of both seasonal and pandemic influenza3, 4. One way to improve early detection is to monitor health-seeking behaviour in the form of queries to online search engines, which are submitted by millions of users around the world each day. Here we present a method of analysing large numbers of Google search queries to track influenza-like illness in a population."

"During wakefulness, we are always conscious of ourselves. In sleep, however, we are not. But there are people, known as lucid dreamers, who can become aware of dreaming during sleep. Studies employing magnetic resonance tomography (MRT) have now been able to demonstrate that a specific cortical network consisting of the right dorsolateral prefrontal cortex, the frontopolar regions and the precuneus is activated when this lucid consciousness is attained. All of these regions are associated with self-reflective functions. This research into lucid dreaming gives the authors of the latest study insight into the neural basis of human consciousness."

"Social interactions require fast and efficient person perception, which is best achieved through the process of categorization. However, this process can produce pernicious outcomes, particularly in the case of stigma. This study used fMRI to investigate the neural correlates involved in forming both explicit ("Do you like or dislike this person?") and implicit ("Is this a male or female?") judgments of people possessing well-established stigmatized conditions (obesity, facial piercings, transsexuality, and unattractiveness), as well as normal controls. Participants also made post-scan disgust ratings on all the faces that they viewed during imaging. These ratings were subsequently examined (modeled linearly) in a parametric analysis. Regions of interest that emerged include areas previously demonstrated to respond to aversive and disgust-inducing material (amygdala and insula), as well as regions strongly associated with inhibition and control (anterior cingulate and lateral prefrontal cortex). Further, greater differences in activation were observed in the implicit condition for both the amygdala and prefrontal cortical regions in response to the most negatively perceived faces. Specifically, as subcortical responses (e.g., amygdala) increased, cortical responses (e.g., lateral PFC and anterior cingulate) also increased, indicating the possibility of inhibitory processing. These findings help elucidate the neural underpinnings of stigma"

"Understanding the relationship between diversity and stability requires a knowledge of how species interact with each other and how each is affected by the environment. The relationship is also complex, because the concept of stability is multifaceted; different types of stability describing different properties of ecosystems lead to multiple diversity-stability relationships. A growing number of empirical studies demonstrate positive diversity-stability relationships. These studies, however, have emphasized only a few types of stability, and they rarely uncover the mechanisms responsible for stability. Because anthropogenic changes often affect stability and diversity simultaneously, diversity-stability relationships cannot be understood outside the context of the environmental drivers affecting both. This shifts attention away from diversity-stability relationships toward the multiple factors, including diversity, that dictate the stability of ecosystems."

This project, the Semantically-Enabled Science Data Integration (SESDI), will demonstrate how ontologies implemented within existing distributed technology frameworks will provide essential, re-useable, and robust, support for an evolution to science measurement processing systems (or frameworks) as well as for data and information systems (or framework) support for NASA Science Focus Areas and Applications.

OCLC ResearchWorks, OCLC's research laboratory. ResearchWorks demonstrates a few of our ideas for applying new technologies to organize information. In some cases, they serve as examples of things you can develop or incorporate into your own systems.

"Everybody likes a simple cause and effect - something we can point to and say (ommitting a few choice words to the perpetrators), 'Fix this and the bees will be right again.' Reality is rarely so straightforward. As the bee decline has progressed I've lost count of the simple 'causes' that have been presented. Among the more memorable are: * mobile 'phones (the absolute 'definite cause' of choice a couple of years ago) * mobile base stations, power lines and other strong electromagnetic sources (a perennial favourite for any malaise) * alien abduction (hopefully they have smaller probes for abducted bees...) * God's punishment (pro gay-marriage states in the USA have more cases of CCD) Leo's article shows neonicotinoids are at least a plausible candidate and they are surely not good for bees, but the argument for these being the explicit 'cause' of global bee decline is still not particularly strong. The risk here is that the media and vocal lobbyists are going off on a righteous crusade to the detriment of more diligent, and maybe less newsworthy, efforts to get to the root of a complex problem. Rather than reviewing the evidence here, I recommend a visit to Randy Oliver's website where his two recent articles from the American Bee Journalon this topic can be found, along with some further commentary on his home page. Interested readers can also directly access the study by Henry et. al. (2012a), the commentry on this study by Creswell and Thompson (2012), the response to the comment (Henry et. al. 2012b) and to the meta-analysis of toxicological studies on imidacloprid by Creswell (2010). An example of one such study is Cutler and Scott-Dupree (2007). Links to all are included below. These are original material rather than reportage and demonstrate the complexity of the issue. As food for thought, I'll leave you with the following: * Neonicotinoids are widely used in Australia and our bees are not (yet) in decline."

"SCinet is a high-performance network that is built, once a year, in support of the annual International Conference for High Performance Computing and Communications also known as the Supercomputing Conference. It is the primary network for the conference and is used by attendees to demonstrate and test high-performance distributed applications."

Results from a DNA study of a young boy's skeletal remains believed to be 24,000 years old could turn the archaeological world upside down -- it's been demonstrated that nearly 30 percent of modern Native American's ancestry came from this youngster's gene pool, suggesting First Americans came directly from Siberia, according to a research team that includes a Texas A&M University professor.

SciVal® Experts is an expertise profiling and research networking tool that helps users find researchers with specific areas of expertise for collaboration and enables researchers in your institution to demonstrate their activities to the global research community. Pre-populated with deep publication histories from Elsevier's Scopus® - the world's largest abstract and citation database of peer-reviewed literature - SciVal Experts makes it easier to find experts and form teams within your institution and across organizations.

"I chose S.thermophilus randomly of the two; I could as easily have chosen L.delbrueckii. Fortunately, I didn't, because Tuur Van Balen, syn-bio-artist extraordinaire, has given a practical demonstration for Next Nature on how to do so!"

"Cathal Garvey demonstrating Do-it-Yourself DNA extraction in a tent from smarimc on Vimeo. Biohackers, like computer hackers before them, need little more than an electronic mailing list to trade tips and information and find the tools they need. DIYbio is by far the largest such list."

The seminar begins with an examination of the fundamental vocabulary and concepts related to metrology. Topics include: accuracy, precision, calibration, and "uncertainty ratios". Several of the standard methods for analyzing measurement variation are then described and explained, as derived from AIAG's Measurement System Analysis reference book. The methods include: Gage R&R (ANOVA method, for 3 gages, 3 persons, 3 replicates, and 10 parts), Gage Correlation (for 3 gages), Gage Linearity, and Gage Bias. The seminar ends with an explanation of how to combine all relevant uncertainty information into an "Uncertainty Budget" that helps determine the appropriate width of QC specification intervals (i.e., "guard-banded specifications"). Spreadsheets are used to demonstrate how to perform the methods described during the seminar.

"(PhysOrg.com) -- Imagine being able to drop a toothpick on the head of one particular person standing among 100,000 people in a stadium. It sounds impossible, yet this degree of precision at the cellular level has been demonstrated by researchers affiliated with the Johns Hopkins University Institute for NanoBioTechnology. Their study was published online in June in Nature Nanotechnology."

"Researchers at Ohio State University have demonstrated the first plastic computer memory device that utilizes the spin of electrons to read and write data. An alternative to traditional microelectronics, the "spintronics" device could store more data in less space, process data faster, and consume less power."

Researchers in the US claim to have demonstrated the first small-scale device to perform all the functions required in large-scale ion-based quantum processing.

Researchers demonstrate a role for the brain's connective tissue in learning a new task

A study that tracked genetic mutations through the human equivalent of about 5,000 years has demonstrated for the first time that oxidative DNA damage is a primary cause of the process of mutation - the fuel for evolution but also a leading cause of aging, cancer and other diseases.

"Basically, any computing device (or switch, or router) that is based on light requires a nonlinear interaction between different light beams, but light doesn't like to do nonlinear stuff. With current technology, you can get efficient nonlinear optical interactions, but the hardware is kind of bulky or very delicate. Not the sort of thing you want to put in a billion devices. What my friends in Barcelona have demonstrated is that it's possible to create a relatively efficient optical nonlinear interaction in a nano-structured metallic surface. "

Purpose of review: Autism is a biologically based disorder of brain development. Genetic factors - mutations, deletions, and copy number variants - are clearly implicated in causation of autism. However, they account for only a small fraction of cases, and do not easily explain key clinical and epidemiological features. This suggests that early environmental exposures also contribute. This review explores this hypothesis. Recent findings: Indirect evidence for an environmental contribution to autism comes from studies demonstrating the sensitivity of the developing brain to external exposures such as lead, ethyl alcohol and methyl mercury. But the most powerful proof-of-concept evidence derives from studies specifically linking autism to exposures in early pregnancy - thalidomide, misoprostol, and valproic acid; maternal rubella infection; and the organophosphate insecticide, chlorpyrifos. There is no credible evidence that vaccines cause autism. Summary: Expanded research is needed into environmental causation of autism. Children today are surrounded by thousands of synthetic chemicals. Two hundred of them are neurotoxic in adult humans, and 1000 more in laboratory models. Yet fewer than 20% of high-volume chemicals have been tested for neurodevelopmental toxicity. I propose a targeted discovery strategy focused on suspect chemicals, which combines expanded toxicological screening, neurobiological research and prospective epidemiological studies.