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Until very recently it was thought that just one bacterium was to blame for causing Lyme disease in humans. But it turns out that a second, related bug can cause it too.

The scientists are from the Centers for Disease Control and Prevention, and they have embarked on this watery journey to solve a decades-old mystery about a rare and fatal disease: monkeypox. A cousin to the deadly smallpox virus, the monkeypox virus initially infects people through contact with wild animals and can then spread from person to person. The disease produces fever and a rash that often turns into painful lesions that can feel like cigarette burns. It kills up to 1 in 10 of its victims, similar to pneumonic plague, and is particularly dangerous in children. Monkeypox is on the U.S. government list of pathogens such as anthrax and Ebola with the greatest potential to threaten human health. There is no cure.

The world is becoming more urban every day, and the process has been ongoing since the industrial revolution in the 18th century. The United Nations now estimates that 3.9 billion people live in urban centres. The rapid influx of residents is however not universal and the developed countries are already urban, but the big rise in urban population in the next 30 years is expected to be in Asia and Africa. Urbanization leads to many challenges for global health and the epidemiology of infectious diseases. New megacities can be incubators for new epidemics, and zoonotic diseases can spread in a more rapid manner and become worldwide threats. Adequate city planning and surveillance can be powerful tools to improve the global health and decrease the burden of communicable diseases.

The Future of Research is being decided now! While we are fortunate to have a robust system of protections in place that help assure research will provide more benefit than harm, the regulations that guide research with human participants have been in place for 40 years. Society is changing, technology is changing, the capabilities and interests of all of us are changing. We need to evolve our research systems too. It is increasingly hard for one group to decide what would be considered a benefit, or a harm, for another. In this new People Matter Project video, we call to institutions and Institutional Review Boards (IRBs) to think creatively about how to conduct trustworthy research in this changing climate.

A team of scientists, in a groundbreaking analysis of data from hundreds of sources, has concluded that humans are on the verge of causing unprecedented damage to the oceans and the animals living in them. "We may be sitting on a precipice of a major extinction event," said Douglas J. McCauley, an ecologist at the University of California, Santa Barbara, and an author of the new research, which was published on Thursday in the journal Science.

The human large intestine (colon), in healthy individuals, has extremely low oxygen concentrations, and over 90% of its microbiota are strict anaerobes. Researchers taking metagenomic fecal microbiota surveys of adult Europeans could assign about 0.8% of the genes in their dataset to archaea [9], and similar numbers (0.2%-0.3%) were reported for Amerindians and Malwaians [10], while North Americans had much lower fractions (<0.05%).

In a striking advance that helps open the door to organ transplants from animals, researchers have created gene-edited piglets cleansed of viruses that might cause disease in humans.

American Museum of Natural History Explore the natural world with Science Bulletins; our documentary Feature Stories, Data Visualizations, and News updates focus on recent discoveries and new technologies in astrophysics, Earth science, biodiversity, and human health and evolution.

mpacts and adaptations of climate change across the major regions of the US. Also broken down across 10 sectors-agriculture, coasts, ecosystems, energy, human ,health, etc. 

Water is essentially everywhere in our world, and the average human is composed of between 55 and 60% water. So what role does water play in our bodies, and how much do we actually need to drink to stay healthy? Mia Nacamulli details the health benefits of hydration.

The Genome Institute (TGI) is a world leader in the fast-paced, constantly changing field of genomics. A truly unique institution, we are pushing the limits of academic research by creating, testing, and implementing new approaches to the study of biology with the goal of understanding human health and disease, as well as evolution and the biology of other organisms.

[ February 17, 2008 ] People who lack a certain large segment of DNA have a previously unrecognized syndrome characterized by mental retardation, seizures, and slight physical abnormalities, according to a genetic analysis conducted by HHMI investigator Evan E. Eichler at the University of Washington School of Medicine and a team of international collaborators. The deleted DNA segment is responsible for just a small percentage of cases of mental retardation, but "when you think about how common mental retardation is," Eichler says, "this deletion has a significant impact on human health."

Bedbugs are a growing public health issue in the United States and around the world, but their resurgence in recent years may have been aided by humans who unwittingly helped the pests evolve numerous ways of thwarting a common insecticide, scientists say.

Biotech foods ('GMOs') are safe. Period. That may seem like a bold statement, but it comes with the weight of a huge body of research and global consensus among preeminent health organizations. To understand the safety of food biotech, it helps to look at the numbers. There are thousands of studies on biotech crops published, billions of pounds of biotech foods eaten, and there are zero illnesses (human or animal) resulting of consuming biotech foods.

Understanding the variability in human hair isn't only interesting from a cosmetic perspective-it also informs the study of evolution. Hair can signal social status, health and fertility, and regulates body temperature.

As the prevalence of genetically modified organisms (GMOs) continues to rise, there has been an increasing public interest for information concerning the safety of these products. Concerns generally focus on how the GMO may affect the environment or how it may affect the consumer. One specific concern is the possibility for GMOs to negatively affect human health. This could result from differences in nutritional content, allergic response, or undesired side effects such as toxicity, organ damage, or gene transfer.

In July, the AP reported that its first round of tests showed disease-causing viruses directly linked to human sewage at levels up to 1.7 million times what would be considered highly alarming in the U.S. or Europe. Experts said athletes were competing in the viral equivalent of raw sewage and exposure to dangerous health risks almost certain. The results sent shockwaves through the global athletic community, with sports officials pledging to do their own viral testing to ensure the waters were safe for competition in next year's games. Those promises took on further urgency in August, after pre-Olympic rowing and sailing events in Rio led to illnesses among athletes nearly double the acceptable limit in the U.S. for swimmers in recreational waters.

Hear from some of the country's leading scientists and medical experts who talk about why animal research is critical for medical progress and the advancement of both human and animal health.

This flipped case study tells the story of Joyce, a biology student who notices the development of some unusual symptoms (foot slapping and slurred speech) in her mother. In an effort to understand the cause, Joyce views a documentary-style trigger video (created by the case author) that suggests to Joyce that her mom may in fact have amyotrophic lateral sclerosis or ALS. The rest of the case walks Joyce through understanding how normal neurons compare to neurons in ALS patients and how that might affect muscle function. The case explores the link between genes, particularly SOD-1, to the formation of malformed proteins and its potential role in the development of ALS. The case concludes with a discussion of drug development and highlights the timeline and costs associated with drug discovery as Joyce becomes concerned about the lack of drugs in the pipeline for ALS, which her mother is ultimately diagnosed with. The case is appropriate for a number of classes including general biology, biotechnology, anatomy and physiology, upper level-cell biology, or any human health and disease-related course.

This interrupted case study for the flipped classroom applies evolutionary genetics research to human health. Students learn about a naturally occurring, but rare, allele of the CCR5 gene, CCR5-Δ32, which provides resistance to HIV. They use data from primary literature sources to predict and interpret worldwide patterns of CCR5-Δ32 frequency distribution. They then discuss how these allele frequency patterns may have been driven by selection imposed by various diseases or by other evolutionary mechanisms. Next, they test published data using Hardy-Weinberg equilibrium to examine if CCR5-Δ32 also provides genetic resistance to West Nile virus. Finally, they complete a jigsaw discussion of Nature News articles that report on how CCR5 research is being used to develop therapies to treat HIV. Originally written for the evolution portion of a yearlong biology series for undergraduate majors, the case is also appropriate for some non-majors biology courses or, with added complexity, upper-level evolution, genetics, or cell biology courses.