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Scientists have confirmed that the pathogen that causes Lyme Disease -- unlike any other known organism -- can exist without iron, a metal that all other life needs to make proteins and enzymes. Instead of iron, the bacteria substitute manganese to make an essential enzyme, thus eluding immune system defenses that protect the body by starving pathogens of iron.

American Museum of Natural History Explore the natural world with Science Bulletins; our documentary Feature Stories, Data Visualizations, and News updates focus on recent discoveries and new technologies in astrophysics, Earth science, biodiversity, and human health and evolution.

In this case study students are provided with information for piecing together the story of how forest fragmentation and biodiversity loss can affect the risk of Lyme disease transmission to humans. The case introduces the dilution effect, a widely accepted theory-and one of the most important ideas in disease ecology-which suggests that disease risk for humans decreases as the diversity of species in an area increases. It also explains how landscape fragmentation, one of the most common threats to biodiversity, can influence the risk of Lyme disease for humans. Students interpret and discuss various figures to develop a concept map that connects all the individual results of the story. Students gain an appreciation for the complexity of species interactions in an ecosystem, the effects of forest fragmentation on these interactions and the possible consequences for human health. This activity was developed for an undergraduate introduction to environmental sciences course under the topic of biodiversity and conservation, but would also be suitable for interdisciplinary studies interested in examining the connections between conservation and public health.

Until very recently it was thought that just one bacterium was to blame for causing Lyme disease in humans. But it turns out that a second, related bug can cause it too.