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Life sciences focus on all things living, exploring the patterns, processes and relationships of organisms. The goal of life sciences is to demonstrate how unifying principles can help us to make sense of the natural world and solve problems in the world we live in. High school life sciences extend student knowledge of topics such as organisms, ecosystems, heredity and evolution, integrating a long history of scientific research from multiple fields. In high school, students will build on their conceptual understanding of life sciences by investigating and witnessing the relationships among structure and function, matter and energy, ecosystems and natural selection. Students should be able to effectively communicate facts and findings, as supported in the science literacy skills covered in the Common Core State Standards.

Online museum in UK.   Explore the home of human ingenuity online. Find out about our objects, arts projects and medical collection, play educational games and discover climate science. Plus check out our blogs, a tabloid history of science and the latest contemporary science news from the Antenna team.

This case study details the historical discovery of the structure of DNA. Images of this key molecule are as iconic as those of the Mona Lisa, and identifying its structure has proven to be as intriguing a mystery for scientists as the reason behind Mona Lisa's smile has been for art historians. The case is woven together by a series of fictional diary entries that detail the history of the discovery of DNA's structure, the major players involved, their ethical dilemmas, and the role of women in science. The case is designed for a high school course or introductory undergraduate genetics/ biochemistry courses. It can also be used as an interdisciplinary case study bridging genetics, bioethics, art, and the status of women in science. Designed as an interrupted case, it may be used in its entirety or in parts that pertain to a particular topic or discipline. No prior knowledge of genetics is required.

This case is an account of the events that led Drs. Robin Warren and Barry Marshall to the bacterial theory of ulcers. The two physicians refused to accept the standard explanations for what they had observed and instead developed an alternative hypothesis, saving countless patients from unnecessary pain and suffering. Along the way they transformed the way the medical community viewed peptic ulcer disease. The case shows the importance of curiosity, serendipity, and tenacity in scientific inquiry; how science is built upon the work of others; how assumptions can cloud people's views, leaving them closed to new ideas; and how scientific "truth" can and does change when faced with new data and new interpretations. It is appropriate for use in any course at the high school or undergraduate level that teaches students about the scientific method and/or the sociology, nature, and history of science.

Science is working tirelessly night and day to disprove its own theories about how the universe works (or at least, that's what science thinks it's doing). Hank tells us a quick history of how we came to create and adopt the scientific method and then gives us a vision of the future of science (hint: it involves a lot more computers and a lot less pipetting).

This case study provides an overview of the seminal experimental work that led to the discovery of DNA structure and the confirmation of the semi-conservative model of DNA replication. By guiding students through a chronological series of historic experiments and discussing some of the collaborations and controversies involved in the original research, students learn about the history and nature of science in addition to several important biological concepts. A number of recommended videos, including one created by the author, enable instructors to use the "flipped-classroom" mode of instruction according to which students read primary literature and watch videos on their own before group discussions and activities. The case study was developed for use in an introductory undergraduate biology course, and would also be appropriate for use in a high school biology course. Some prior knowledge or instruction may be required, depending on the level and learning objectives of the course.

The data comes from the open Tree of Life Project, a collaboration among biologists and other scientists around the world. It contains decades' worth of work in phylogeny, evolutionary history of and relationships among groups of organisms. The project is about a year away from a complete tree of all life, Rosindell said. He wanted a system in place that could visualize it as soon as it's ready. Right now, OneZoom only contains mammals, but that's still more than 5,000 species, all correlated with each other and color-coded according to their threat levels. Rosindell has big plans for the rest, and he even wants to build a searchable app for smartphones, showcasing the history and relationships between all life on Earth.

For centuries, women have studied and made groundbreaking discoveries in STEM (Science, Technology, Engineering, and Mathematics) fields. Encourage your girls and boys to appreciate the contributions of women scientists. With our seven ideas, learn about some outstanding women from the history of STEM innovation and inspire your kids' scientific explorations - indoors and outdoors.

Currently there is considerable confusion surrounding the use of the term "organic" as applied to food and other consumer products, but within the agriculture industry the term has a well-defined meaning related to the practices that are allowed in the production of a crop. This case study was written to inform students about organic agriculture and its implications with regard to food nutritional value as well as its costs.  The case is presented as a dilemma in the context of buying produce in the grocery store. Concepts presented include the difference between organic and conventional agricultural practices, the analysis of food to quantify nutrient levels, the history of the organic movement, and the economic and environmental impacts of organic agriculture. The activity was designed for use in a lower level general science course (with a cursory review of the scientific literature) or in an upper level chemistry course (with a thorough analysis of the literature).

This directed case study follows the story of "Pauline," a 20-year-old college student who has just received results from a personal genetic testing kit she purchased online. The report shows a negative result for variants of the BRCA 1 and 2 genes, which are associated with a greater risk for breast cancer. Although Pauline has a family history of breast cancer, she concludes that she no longer needs to be concerned, or does she? As students work through the questions in this case study, they review the role of genes and how they code for proteins as well as the effects of proteins on health, especially on cellular growth regulation and cancer. They also learn about the process of genetic testing and consider the ramifications of positive and negative tests for diseases or health conditions, especially with respect to breast cancer. The case is designed for non-science majors in a scientific methods course and could also be used in an introductory biology course. The questions in the case could be adapted for an upper level genetics class.

Before the discovery of insulin in 1921, being diagnosed with Type 1 diabetes was a death sentence. Despite the successful management of diabetes with purified animal insulin, potentially severe side effects were abundant, and alternative ways to produce insulin were needed. This case study guides students through the history of using insulin to treat diabetes, focusing on the development of recombinant DNA technology and the world's first bioengineered drug, recombinant human insulin, which is now used worldwide to treat diabetes. Through the course of this case, students consider the central dogma of molecular biology, the development of recombinant DNA technology, drug design, the importance of recombinant proteins to our society, and the ethical analysis and debates that occur as a result of some scientific discoveries. This case was developed as an introduction to an upper-division biotechnology course focusing on recombinant protein design and production, but could also be used in molecular biology, biochemistry, or introductory biology courses to highlight recombinant DNA and biotechnology.

American Museum of Natural History Explore the natural world with Science Bulletins; our documentary Feature Stories, Data Visualizations, and News updates focus on recent discoveries and new technologies in astrophysics, Earth science, biodiversity, and human health and evolution.

Fascinating narrative science that explores the next frontier in medicine and genetics through the very personal prism of the children and families gene therapy has touched. Eight-year-old Corey Haas was nearly blind from a hereditary disorder when his sight was restored through a delicate procedure that made medical history.  Like something from a science fiction novel, doctors carefully introduced viruses bearing healing genes into Corey's eyes-a few days later, Corey could see, his sight restored by gene therapy.

In this directed case study students follow a nurse practitioner and work with a diagnostics team to determine what is wrong with Tristan, an infant who comes to the clinic with multiple bruises. Students are given background and patient history, and are then given results of various blood tests ordered by the diagnostics team. The exercise emphasizes the physiological process of coagulation and the importance of various clotting factors, especially factor VIII. Students will be introduced to results from several blood tests, including: complete blood count, partial thromboplastin time, prothrombin time, metabolic panel, and factor VIII assay. The patient is ultimately diagnosed with severe hemophilia A and the case then introduces students to this disorder, the genetic determinants, the incidence, and ways to manage the disease. The data in this case are real and the story represents the medical history of an actual patient. Originally developed for pre-nursing students, this activity would also be suitable for majors in physiology or pre-medical students; it could also be used in an introductory genetics or biology course.

Sulston worked alone, in silence, hunched over a microscope for eight hours a day. By studying and drawing worms of various ages, he figured out the ancestor and descendants of each of their cells. It was a monumental piece of science. Sulston mapped the complete history of an individual, the comprehensive family tree of a single body. "We had the entire story of the worm's cells from fertilized egg to adult," he later said, upon accepting the Nobel Prize for his work.

This case study teaches students about allopatric speciation through an investigation of the benthic and limnetic sticklebacks of Paxton Lake, which are among the youngest species on Earth, diverging from each other after the Pleistocene glaciers melted and the Gulf Islands formed. Researchers at the University of British Columbia have carried out a variety of fascinating studies on these hardy little fish. Results from this research (formatted as data sheets included in the teaching notes) are provided to students who design experiments and then compare actual data to investigate why benthic and limnetic sticklebacks seldom interbreed in Paxton Lake. Developed for a first-year biology course for majors organized around the general theme of evolution and the history of life on Earth, this case study is an updated version of another case in the collection, "Something's Fishy in Paxton Lake" (Sharp, 2001). The current version is especially suited for a flipped classroom in which students prepare for class ahead of time with a reading assignment that also involves the viewing of a video by the case authors that introduces the mechanisms of allopatric speciation.

The fates of ice age human groups in Europe were closely linked to climate change, according to an unprecedented study of the genomes of 51 individuals who lived between 45,000 years ago (when modern humans arrived in Europe) and 7,000 years ago. "We see multiple, huge movements of people displacing previous ones," David Reich of the Harvard Medical School said. "During this first four-fifths of modern human history in Europe, history is just as complicated as it is during the last fifth that we know so much more about." 

This case study examines the molecular methods that were used to reverse engineer the 1918 influenza virus strain in order to try and solve the mystery of why it was so deadly. The story starts in the 1950s with the unsuccessful attempts to culture the influenza virus and follows scientists through to the turn of the century when cutting edge molecular tools enabled scientists to finally resurrect the 1918 virus through reverse genetics. The history and methods involved in resurrecting this deadly virus are reviewed in class with a PowerPoint presentation containing clicker questions (answered with a personal response system) and discussion questions (answered in small groups). This "clicker case" is suitable for high school biology and lower division undergraduate biology classes for non-majors. It could also be used in any lower division non-major class focused on human disease and the history of human disease.

A common misconception is that Darwin suggested that something as complex as the eye could not have evolved through natural selection. While the misunderstanding often comes from an incomplete reading of his argument, we have long known that intermediate varieties of eyes (e.g., eyespots, cupped eyes, and complex camera-type eyes) exist in a variety of organisms. Eyes are so common that it was thought that they had evolved independently 40-60 times. More recent molecular work, however, has identified the role of Pax6 genes and their homologs in the formation of eyes during development. The basic information for eye formation appears to have been present in the common ancestor to all bilaterans, and perhaps may be more ancient than that. This interrupted case study examines the history of evidence for eye evolution from Darwin's initial postulates, through evidence of multiple intermediate forms, concluding in an examination of Pax6 homologs. The case is primarily for an introductory biology class but an additional section would be appropriate for upper-level evolution or developmental biology courses.

This interrupted case study explores the role of cytoskeletal structures on human health, specifically on respiratory function, sperm motility, and female fertility. It follows the story of a couple struggling to conceive a child and the doctors working to help them. Students are presented with clinical histories, narrative elements, documentary-style videos, and microscopic evidence in order to determine the cause of the couple's infertility. Along the way, they learn about the three types of cytoskeletal elements and the roles these play in cellular biology and human physiology. The use of videos makes it suitable for the "flipped classroom," allowing students to prepare outside the classroom for the case study, which they then complete in class. An original video by the author on the structure and function of microtubules, microfilaments, and intermediate filaments is included. The case was developed for an introductory level general biology course and could be delivered during a unit on the cell structure and function. The case could also be used in a cell biology course.