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This is the updated Amoeba Sisters human organ systems video, which provides a brief introduction to each of the 11 human organ systems including the circulatory, digestive, endocrine, excretory, integumentary, lymphatic/immune, muscular, nervous, reproductive, respiratory, and skeletal systems.

An elderly woman living independently with some help from her family is brought to the local emergency room because she is confused and vomiting. While her son suspects a stroke, a quick battery of laboratory tests indicates that her current problems are the result of impaired kidney function, an old-fashioned home remedy for ulcers, and her prescribed blood pressure medication. The combination of patient- and drug-related factors produces an acid-base disorder responsible for her confusion. This disorder further disrupts her kidney function. The case illustrates secretion and reabsorption processes in the kidney tubule which regulate plasma and urinary electrolytes (including calcium) and pH. The role of bicarbonate in maintaining systemic pH is emphasized. Interactions among the renal, respiratory and nervous systems in the regulation of systemic pH are also illustrated. Further, basic principles of pharmacotherapy and issues related to the appropriate use of medications are introduced. The case was developed for use in a physiology or human anatomy and physiology course, but it might be used in undergraduate nursing courses as well (e.g., pharmacology, pathophysiology).

This interrupted case study explores the role of cytoskeletal structures on human health, specifically on respiratory function, sperm motility, and female fertility. It follows the story of a couple struggling to conceive a child and the doctors working to help them. Students are presented with clinical histories, narrative elements, documentary-style videos, and microscopic evidence in order to determine the cause of the couple's infertility. Along the way, they learn about the three types of cytoskeletal elements and the roles these play in cellular biology and human physiology. The use of videos makes it suitable for the "flipped classroom," allowing students to prepare outside the classroom for the case study, which they then complete in class. An original video by the author on the structure and function of microtubules, microfilaments, and intermediate filaments is included. The case was developed for an introductory level general biology course and could be delivered during a unit on the cell structure and function. The case could also be used in a cell biology course.

Was the "Brooklyn Butcher" of 1926 a cold-blooded killer or was something less sinister at play? This interrupted case study introduces students to hemoglobin binding and carbon monoxide poisoning by working through the details of a fictionalized account of a true-crime story. Topics covered include molecule conformational states, binding affinity, deoxyhemoglobin, oxyhemoglobin, carboxyhemoglobin, and oxygen transport. Students also design an experiment to determine the cause of death of the victim. Prior to beginning the activity students should have some knowledge of the respiratory and circulatory systems and be familiar with oxygen binding curves. Detailed understanding of hemoglobin conformational changes is not necessary since this information is covered in the case. Students will also learn briefly about the electromagnetic spectrum and visible light. Originally developed for a non-majors, pre-nursing anatomy and physiology course, the case is also appropriate for use in any of the following courses: introductory biochemistry, introductory biology, introductory chemistry, nursing, exercise physiology, or possibly even introductory physics.