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hat is color blindness? A color festival. No. Color blindness or color deficiency is a vision problem. Now, our eyes have light sensitive cells called rods and cones. Can I put ice cream on these cones? You are just unbelievable. Rods are responsible for black and white vision. They do not detect color. Whereas, cones detect color. There are three types of cones. One cone perceives red light, another perceives green and the third perceives blue. Together, these cones help us to see the whole spectrum of colors. Now in some cases, when one or more types of cones do not work properly, it causes color blindness. People with such deficiency have difficulty in distinguishing between certain colors or shades. For example, in red-green color blindness, the apple tree may appear like this.

4 min We tend to think of blindness as something you're born with, but with certain genetic diseases, it can actually develop when you're a kid, or even when you're an adult. But could blind eyes possibly regenerate? David Davila explains how the zebrafish's amazing regenerative retinas are causing scientists to investigate that very question.

Normally, male squirrel monkeys can't distinguish between red and green hues-they're what is called color-blind in humans. The South American Saimiri genus lacks a gene that allows color-sensitive cells in the eye, called cones, to differentiate red and green from gray. To these animals, other colors, such as blue, brown and orange, appear faded. But Sam was one of two males in the experimental group of a groundbreaking 2009 ophthalmological study conducted at the Washington National Primate Research Center in Seattle. Husband-and-wife vision researchers Jay and Maureen Neitz injected a viral vector behind the retinas, the part of the eye that responds to color, of Sam and his simian lab partner, Dalton. The virus contained the genetic code in human eyes for red pigment, giving the monkeys an extra class of cone photoreceptor.

Jackson would eventually be diagnosed with the rare genetic eye disease Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy (ADNIV), which eventually causes blindness in those who carry the gene.

Some people in the world aren't able to see many colors. The condition is called color blindness, but what exactly causes it?

start at 4:00 human genome project translation target rare diseases with gene therapy: 1)Leber's congenital amaurosis- blindness 2) congenitaal AADC deficiency- enzyme responsible for movement 3)  Muscular Dystrophy- Pompe Disease

Fascinating narrative science that explores the next frontier in medicine and genetics through the very personal prism of the children and families gene therapy has touched. Eight-year-old Corey Haas was nearly blind from a hereditary disorder when his sight was restored through a delicate procedure that made medical history.  Like something from a science fiction novel, doctors carefully introduced viruses bearing healing genes into Corey's eyes-a few days later, Corey could see, his sight restored by gene therapy.

A decade-old technique that allows researchers to control brain function in lab animals could partially restore sight to the blind. In a trial sponsored by RetroSense Therapeutics, a startup company in Ann Arbor, Michigan, doctors will inject a harmless virus loaded with DNA from photoreceptive algae into the eyes of 15 patients suffering from retinitis pigmentosa. The experimental procedure represents the first human test of optogenetics, which is a technique that genetically modifies neurons to make them responsive to light. Doctors from the Retina Foundation of the Southwest will perform the procedure, and attempt to transfer the job duties of photoreceptor cells to different cells in the eye to restore sight.

infographic on vision including color blindness

"Biologists at the University of Rochester have determined how blind mole rats fight off cancer -- and the mechanism differs from what they discovered three years ago in another long-lived and cancer-resistant mole rat species, the naked mole rat."

Every year, it inflicts between 250,000 and 500,000 helpless and malnourished young people with early-life blindness. And in half of those cases, it also brings death, according to the World Health Organization. Vitamin A deficiency also puts pregnant women at risk. It's rare in developed countries, but the goal of completely eradicating vitamin A deficiency - mostly in Africa and Southeast Asia - remains unmet. Scientists are now working to genetically engineer "super" bananas that are fortified with crucial alpha- and beta-carotene, which the body converts to vitamin A.

Naked mole rats are hairless, blind, underground dwellers that are remarkably impervious to cancer. But why you ask? Well, researchers at the University of Rochester asked that same question and it turns out a cluster of genes, called the INK4 locus, is the answer. This locus, also found in humans and mice, uses that cluster to carry instructions, or encode, for several cancer fighting proteins.

Technical details aside, Crispr-Cas9 makes it easy, cheap, and fast to move genes around-any genes, in any living thing, from bacteria to people. "These are monumental moments in the history of biomedical research," Baltimore says. "They don't happen every day." Using the three-year-old technique, researchers have already reversed mutations that cause blindness, stopped cancer cells from multiplying, and made cells impervious to the virus that causes AIDS. Agronomists have rendered wheat invulnerable to killer fungi like powdery mildew, hinting at engineered staple crops that can feed a population of 9 billion on an ever-warmer planet. Bioengineers have used Crispr to alter the DNA of yeast so that it consumes plant matter and excretes ethanol, promising an end to reliance on petrochemicals. Startups devoted to Crispr have launched. International pharmaceutical and agricultural companies have spun up Crispr R&D. Two of the most powerful universities in the US are engaged in a vicious war over the basic patent.